Exploring the nuclear proteins, viral capsid protein, and early antigen protein using immunoinformatic and molecular modeling approaches to design a vaccine candidate against Epstein Barr virus.

Autor: Oladipo EK; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, 210214, Nigeria.; Department of Microbiology, Laboratory of Molecular Biology, Immunology and Bioinformatics, Adeleke University, Ede, 232104, Nigeria., Ojo TO; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, 210214, Nigeria.; Computational Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, (LAUTECH), Ogbomoso, 210214, Nigeria., Elegbeleye OE; Computational Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, (LAUTECH), Ogbomoso, 210214, Nigeria., Bolaji OQ; Computational Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, (LAUTECH), Ogbomoso, 210214, Nigeria., Oyewole MP; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, 210214, Nigeria.; Department of Biochemistry, Bowen University, Iwo, 232101, Nigeria., Ogunlana AT; Institute of Advanced Medical Research and Training (IAMRAT), College of Medicine, University of Ibadan, Ibadan, 200005, Nigeria., Olalekan EO; Computational Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, (LAUTECH), Ogbomoso, 210214, Nigeria., Abiodun B; Computational Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, (LAUTECH), Ogbomoso, 210214, Nigeria., Adediran DA; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, 210214, Nigeria., Obideyi OA; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, 210214, Nigeria., Olufemi SE; Division of Vaccine Design and Development, Helix Biogen Institute, Ogbomoso, 210214, Nigeria., Salamatullah AM; Department of Food Science and Nutrition, College of Food and Agricultural Sciences, King Saud University, 11, P.O. Box 2460, 11451, Riyadh, Saudi Arabia., Bourhia M; Laboratory of Therapeutic and Organic Chemistry, Faculty of Pharmacy, University of Montpellier, Montpellier, 34000, France., Younous YA; Evangelical College, BP 1200, N'Djamena, Chad. scientifcresearcher@gmail.com., Adelusi TI; Computational Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, (LAUTECH), Ogbomoso, 210214, Nigeria. tiadelusi@lautech.edu.ng.; Department of Surgery, School of Medicine, University of Connecticut Health, Farmington Ave, Farmington, CT, 06030, USA. tiadelusi@lautech.edu.ng.

Publikováno v: Scientific reports [Sci Rep] 2024 Jul 22; Vol. 14 (1), pp. 16798. Date of Electronic Publication: 2024 Jul 22.

Predicting Plasmodium falciparum kinase inhibitors from antimalarial medicinal herbs using computational modeling approach.

Autor: Adelusi TI; Computational Molecular Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, P.M.B 210214, Ogbomoso, Oyo State Nigeria., Ojo TO; Computational Molecular Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, P.M.B 210214, Ogbomoso, Oyo State Nigeria.; Genomics unit, Helix Biogen Institute, P.M.B 212102, Ogbomoso, Oyo State Nigeria., Bolaji OQ; Computational Molecular Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, P.M.B 210214, Ogbomoso, Oyo State Nigeria., Oyewole MP; Computational Molecular Biology and Drug Discovery Laboratory, Department of Biochemistry, Ladoke Akintola University of Technology, P.M.B 210214, Ogbomoso, Oyo State Nigeria., Olaoba OT; Department of Molecular Microbiology and Immunology, University of Missouri, Columbia, MO 65211 USA., Oladipo EK; Genomics unit, Helix Biogen Institute, P.M.B 212102, Ogbomoso, Oyo State Nigeria.; Laboratory of Molecular Biology, Bioinformatics and Immunology, Department of Microbiology, Adeleke University, Ede, Osun State Nigeria.

Publikováno v: In silico pharmacology [In Silico Pharmacol] 2023 Dec 19; Vol. 12 (1), pp. 4. Date of Electronic Publication: 2023 Dec 19 (Print Publication: 2024).

Designing a conserved peptide-based subunit vaccine against SARS-CoV-2 using immunoinformatics approach.

Autor: Oladipo EK; Department of Microbiology, Laboratory of Molecular Biology, Immunology and Bioinformatics, Adeleke University, Ede, Osun State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Ajayi AF; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria., Onile OS; Biotechnology Programme, Department of Biological Sciences, Elizade University, Ilara-Mokin, Nigeria., Ariyo OE; Department of Medicine, Infectious Diseases and Tropical Medicine Unit, Federal Teaching Hospital, Ido-Ekiti, Ekiti State Nigeria., Jimah EM; Department of Medical Microbiology and Parasitology, University of Ilorin, Ilorin, Kwara State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Ezediuno LO; Department of Microbiology and Parasitology, University of Ilorin, Ilorin, Kwara State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Adebayo OI; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Adebayo ET; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Odeyemi AN; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Oyeleke MO; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria., Oyewole MP; Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria., Oguntomi AS; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Akindiya OE; Microbiology Programme, Department of Biological Science, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State Nigeria., Aremu VO; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo State Nigeria., Aboderin DO; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos, Lagos State Nigeria., Oloke JK; Department of Natural Sciences, Precious Cornerstone University, Ibadan, Oyo State Nigeria.

Publikováno v: In silico pharmacology [In Silico Pharmacol] 2021 Jan 06; Vol. 9 (1), pp. 8. Date of Electronic Publication: 2021 Jan 06 (Print Publication: 2021).

Exploration of surface glycoprotein to design multi-epitope vaccine for the prevention of Covid-19.

Autor: Oladipo EK; Department of Microbiology, Laboratory of Molecular Biology, Immunology and Bioinformatics, Adeleke University, Ede, Osun State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Ajayi AF; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Ariyo OE; Department of Medicine, Infectious Diseases and Tropical Medicine Unit, Federal Teaching Hospital, Ido-Ekiti, Ekiti State, Nigeria., Onile SO; Biotechnology Programme, Department of Biological Sciences, Elizade University, Nigeria., Jimah EM; Department of Medical Microbiology and Parasitology, University of Ilorin, Kwara State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Ezediuno LO; Department of Microbiology and Parasitology, University of Ilorin, Kwara State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Adebayo OI; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Adebayo ET; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Odeyemi AN; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Oyeleke MO; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Oyewole MP; Department of Biochemistry, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Oguntomi AS; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Akindiya OE; Microbiology Programme, Department of Biological Science, Olusegun Agagu University of Science and Technology, Okitipupa, Ondo State, Nigeria., Olamoyegun BO; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Aremu VO; Reproduction and Bioinformatics Unit, Department of Medical Physiology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria.; Genomics Unit, Helix Biogen Consult, Ogbomoso, Oyo state, Nigeria., Arowosaye AO; Department of Virology, University of Ibadan, Ibadan, Oyo State, Nigeria., Aboderin DO; Department of Medical Microbiology and Parasitology, University of Lagos, Lagos State, Nigeria., Bello HB; Department of Microbiology, Kebbi State University, Aliero, Kebbi State, Nigeria., Senbadejo TY; Department of Microbiology, Fountain University, Osogbo, Osun State, Nigeria., Awoyelu EH; Department of Natural Sciences, Precious Conerstone University, Ibadan, Oyo State, Nigeria., Oladipo AA; Department of Haematology and Blood Grouping Serology, Obafemi Awolowo Teaching Hospital Complex, Ile-Ife Wesley Guild Hospital Wing, Osun State, Nigeria., Oladipo BB; Department of Clinical Nursing, Bowen University Teaching Hospital, Ogbomoso, Oyo State, Nigeria., Ajayi LO; Department of Biochemistry, Adeleke University, Ede, Osun State, Nigeria., Majolagbe ON; Department of Pure and Applied Biology, Ladoke Akintola University of Technology, Ogbomoso, Oyo State, Nigeria., Oyawoye OM; Department of Microbiology, Laboratory of Molecular Biology, Immunology and Bioinformatics, Adeleke University, Ede, Osun State, Nigeria., Oloke JK; Department of Natural Sciences, Precious Conerstone University, Ibadan, Oyo State, Nigeria.

Publikováno v: Informatics in medicine unlocked [Inform Med Unlocked] 2020; Vol. 21, pp. 100438. Date of Electronic Publication: 2020 Oct 04.