Zobrazeno 1 - 10
of 703
pro vyhledávání: '"Oxygen and glucose deprivation"'
Autor:
Paloma Mata, Stefano Calovi, Kami Pars Benli, Leyre Iglesias, María Isabel Hernández, Abraham Martín, Alberto Pérez-Samartín, Ander Ramos-Murguialday, María Domercq, Iñaki Ortego-Isasa
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Ischemic stroke consists of rapid neural death as a consequence of brain vessel obstruction, followed by damage to the neighboring tissue known as ischemic penumbra. The cerebral tissue in the core of the lesions becomes irreversibly damaged, however
Externí odkaz:
https://doaj.org/article/c4f73d28db37476c8b78307b7bb6ee9c
Publikováno v:
Heliyon, Vol 10, Iss 17, Pp e37276- (2024)
Objective: The present study aims to evaluate the impact of Astilbin (AST) on cortical neuron survival in vitro under conditions of oxygen-glucose deprivation and reoxygenation (OGD/R) and determine the role of NF-E2-related factor 2 (Nrf2) in this p
Externí odkaz:
https://doaj.org/article/b3a19f9882214c01b8f7a03de0451453
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 2, Pp 255-257 (2024)
During brain ischemia, excitotoxicity and peri-infarct depolarization injuries occur and cause cerebral tissue damage. Indeed, anoxic depolarization, consisting of massive neuronal depolarization due to the loss of membrane ion gradients, occurs in v
Externí odkaz:
https://doaj.org/article/42accd31e1c74a7ca015b53bee76921e
Publikováno v:
Acta Biochimica et Biophysica Sinica, Vol 55, Pp 1415-1424 (2023)
Stroke seriously threatens human life and health worldwide, but only very few effective stroke medicines are currently available. Our previous studies have indicated that the phytoestrogen calycosin exerts neuroprotective effects in cerebral ischemia
Externí odkaz:
https://doaj.org/article/8fa2f2482261418188a195fa9393c236
Autor:
Guoqi Cao, Siyuan Yin, Jiaxu Ma, Yongpan Lu, Ru Song, Zhenjie Wu, Chunyan Liu, Jian Liu, Peng Wu, Rui Sun, Aoyu Chen, Yibing Wang
Publikováno v:
Heliyon, Vol 10, Iss 2, Pp e24602- (2024)
The impaired healing of chronic wounds is often attributed to the ischemic and hypoxic microenvironment, leading to increased cell death. Ferroptosis, a novel form of cell death unveiled in recent years, could potentially be linked with the process o
Externí odkaz:
https://doaj.org/article/8aaf240a0f954f31a4ca506b0642deda
Publikováno v:
Asian Pacific Journal of Tropical Biomedicine, Vol 13, Iss 2, Pp 70-79 (2023)
Objective: To evaluate the effect of salidroside on oxygen and glucose deprivation (OGD)-treated NT2 cells and its underlying mechanisms of action. Methods: Retinoic acid was used to induce the differentiation of NT2 cells into neurons. The effects o
Externí odkaz:
https://doaj.org/article/898c51384dfe437da0c6df0ed2d6214c
Publikováno v:
Iranian Journal of Basic Medical Sciences, Vol 26, Iss 1, Pp 30-36 (2023)
Objective(s): Epicardial adipose tissue (EpAT) is known for its role in supporting the cardiomyocytes. Lysine-specific demethylase 1 (LSD1), a typical lysine demethylase, is an essential regulator for the maintenance of beige adipocytes. However, the
Externí odkaz:
https://doaj.org/article/715102bba413412aa831634ab9ef0781
Publikováno v:
Neural Regeneration Research, Vol 18, Iss 6, Pp 1332-1338 (2023)
Mitochondrial damage caused by oxidative stress and energy deficiency induced by focal ischemia and hypoxia are important factors that aggravate diseases. Studies have shown that ginsenoside Rb1 has neurotrophic and neuroprotective effects. However,
Externí odkaz:
https://doaj.org/article/4d098978ffb0408f9fe4e5a9f8927b8a
Akademický článek
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Publikováno v:
MedComm – Oncology, Vol 2, Iss 2, Pp n/a-n/a (2023)
Abstract In this study, we aimed to determine the specific roles of death‐associated protein kinase 1 (DAPK1) and Beclin1 in non‐small cell lung cancer (NSCLC) under oxygen and glucose deprivation (OGD). We found that OGD caused most cells to shr
Externí odkaz:
https://doaj.org/article/29b3bc9d68474637969a62a05f2031ff