Zobrazeno 1 - 10
of 2 418
pro vyhledávání: '"Oxoglutarate"'
Autor:
Anna Spagnoletta, Daniela Valeria Miniero, Nicola Gambacorta, Francesca Oppedisano, Anna De Grassi, Orazio Nicolotti, Ciro Leonardo Pierri, Annalisa De Palma
Publikováno v:
Molecules, Vol 29, Iss 21, p 5154 (2024)
The 2-oxoglutarate carrier (OGC), pivotal in cellular metabolism, facilitates the exchange of key metabolites between mitochondria and cytosol. This study explores the influence of NADPH on OGC transport activity using proteoliposomes. Experimental d
Externí odkaz:
https://doaj.org/article/e2e22f0a3a944c2d91807c5b3ead90cd
Akademický článek
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Autor:
Wei Quan, Hui-xian Liu, Wei Zhang, Wei-juan Lou, Yang-ze Gong, Chong Yuan, Qing Shao, Na Wang, Chao Guo, Fei Liu
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 222-231 (2021)
Context Rosmarinic acid (RosA), a natural poly-phenolic compound isolated from a variety of Labiatae herbs, has been reported to have a range of biological effects. Objective To investigate the cardioprotective effects of RosA against myocardial isch
Externí odkaz:
https://doaj.org/article/6053e8d1a63c4487a5bd134dc7a188c0
Autor:
Laura Prioretti, Giulia D’Ermo, Pascale Infossi, Arlette Kpebe, Régine Lebrun, Marielle Bauzan, Elisabeth Lojou, Bruno Guigliarelli, Marie-Thérèse Giudici-Orticoni, Marianne Guiral
Publikováno v:
Life, Vol 13, Iss 3, p 627 (2023)
Aquifex aeolicus is a microaerophilic hydrogen- and sulfur -oxidizing bacterium that assimilates CO2 via the reverse tricarboxylic acid cycle (rTCA). Key enzymes of this pathway are pyruvate:ferredoxin oxidoreductase (PFOR) and 2-oxoglutarate:ferredo
Externí odkaz:
https://doaj.org/article/0a5d4ac7e1c94ea1be917d66c7ecfd3c
Autor:
Gergő Horváth, Gergely Sváb, Tímea Komlódi, Dora Ravasz, Gergely Kacsó, Judit Doczi, Christos Chinopoulos, Attila Ambrus, László Tretter
Publikováno v:
Antioxidants, Vol 11, Iss 8, p 1487 (2022)
α-ketoglutarate dehydrogenase complex (KGDHc), or 2-oxoglutarate dehydrogenase complex (OGDHc) is a rate-limiting enzyme in the tricarboxylic acid cycle, that has been identified in neurodegenerative diseases such as in Alzheimer’s disease. The ai
Externí odkaz:
https://doaj.org/article/e63f5b161a524c698f8f6f43744d2db7
Akademický článek
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Autor:
Yongming Liu, Gui Wei, Yuanyan Xia, Xiaowei Liu, Jin Tang, Yanli Lu, Hai Lan, Suzhi Zhang, Chuan Li, Moju Cao
Publikováno v:
BMC Plant Biology, Vol 18, Iss 1, Pp 1-14 (2018)
Abstract Background C-type cytoplasmic male sterility (CMS-C) is one of the three major types of cytoplasmic male sterility (CMS) in maize. Rf4 is a dominant restorer gene for CMS-C and has great value in hybrid maize breeding, but little information
Externí odkaz:
https://doaj.org/article/5e24956ab8b545b6bc9a8fc19a413b4d
Akademický článek
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Autor:
Eric L. Allen, Danielle B. Ulanet, David Pirman, Christopher E. Mahoney, John Coco, Yaguang Si, Ying Chen, Lingling Huang, Jinmin Ren, Sung Choe, Michelle F. Clasquin, Erin Artin, Zi Peng Fan, Giovanni Cianchetta, Joshua Murtie, Marion Dorsch, Shengfang Jin, Gromoslaw A. Smolen
Publikováno v:
Cell Reports, Vol 17, Iss 3, Pp 876-890 (2016)
Although aberrant metabolism in tumors has been well described, the identification of cancer subsets with particular metabolic vulnerabilities has remained challenging. Here, we conducted an siRNA screen focusing on enzymes involved in the tricarboxy
Externí odkaz:
https://doaj.org/article/038a8ba083f6473f859242fde11df665
Autor:
Ella F. Whittle, Madison Chilian, Ehsan Ghayoor Karimiani, Helga Progri, Daniela Buhas, Melis Kose, Rebecca D. Ganetzky, Mehran Beiraghi Toosi, Paria Najarzadeh Torbati, Reza Shervin Badv, Ivan Shelihan, Hui Yang, Houda Zghal Elloumi, Sukyeong Lee, Yalda Jamshidi, Alan M. Pittman, Henry Houlden, Erika Ignatius, Shamima Rahman, Reza Maroofian, Wan Hee Yoon, Christopher J. Carroll
Purpose: This study aimed to establish the genetic cause of a novel autosomal recessive neurodevelopmental disorder characterized by global developmental delay, movement disorder, and metabolic abnormalities.Methods: We performed a detailed clinical
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8223f73bbd5b707e1c5d859eb2bb697e
http://hdl.handle.net/10138/356336
http://hdl.handle.net/10138/356336