Zobrazeno 1 - 10
of 8 485
pro vyhledávání: '"Oxidative DNA Damage"'
Publikováno v:
DNA, Vol 4, Iss 3, Pp 221-238 (2024)
Oxidative stress-mediated biomolecular damage is a characteristic feature of ionizing radiation (IR) injury, leading to genomic instability and chronic health implications. Specifically, a dose- and linear energy transfer (LET)-dependent persistent i
Externí odkaz:
https://doaj.org/article/8a4d9ac376e940bf8cd8ee373c28b016
Publikováno v:
International Journal of Yoga, Vol 17, Iss 1, Pp 10-19 (2024)
Infertility, a widespread medical condition affecting numerous couples globally, persists as a challenge despite advances in assisted reproductive technologies (ARTs), often burdened by financial, physical, and emotional strains. Complementary and al
Externí odkaz:
https://doaj.org/article/8ff60e28512541c99478efcc2ad4d413
Autor:
Marianna Kapetanou, Sophia Athanasopoulou, Andreas Goutas, Dimitra Makatsori, Varvara Trachana, Efstathios Gonos
Publikováno v:
Antioxidants, Vol 13, Iss 10, p 1258 (2024)
Cellular senescence is a hallmark of aging characterized by irreversible growth arrest and functional decline. Progressive telomeric DNA shortening in dividing somatic cells, programmed during development, leads to critically short telomeres that tri
Externí odkaz:
https://doaj.org/article/ff098894dcc343c4bc150c8a5e3217f1
Autor:
María Castejón-Griñán, Sonia Cerdido, José Sánchez-Beltrán, Ana Lambertos, Marta Abrisqueta, Cecilia Herraiz, Celia Jiménez-Cervantes, José Carlos García-Borrón
Publikováno v:
Redox Biology, Vol 72, Iss , Pp 103135- (2024)
Cutaneous melanoma, a lethal skin cancer, arises from malignant transformation of melanocytes. Solar ultraviolet radiation (UVR) is a major environmental risk factor for melanoma since its interaction with the skin generates DNA damage, either direct
Externí odkaz:
https://doaj.org/article/ba0a1e95cb73498d8a5a5f348a60c744
Publikováno v:
Bulgarian Journal of Veterinary Medicine, Vol 26, Iss 3, Pp 399-409 (2023)
The current study aimed to evaluate the effect of olive oil (OLO) on the genotoxicity of imidacloprid (IMI). Rats were divided into four groups: control group, IMI group that was exposed to 22.5 mg/kg b.w. IMI for 4, 8, and 12 weeks; OLO before IMI g
Externí odkaz:
https://doaj.org/article/5ab10011901f4ff683a3cb78301e4af1
Autor:
Odewusi Odeyinka O, Ogberetitinor Ofejiro B, Ijeh Wendy A, Obadire Olalere S, Olaniyan Olayinka O
Publikováno v:
Journal of Krishna Institute of Medical Sciences University, Vol 12, Iss 3, Pp 50-62 (2023)
Background: Oxidative stress is a major factor in the pathogenesis and progression of the clinical condition type 2 Diabetes Mellitus (DM) related to adverse biochemical/molecular interactions. Aim and Objectives: To determine whether haptoglobin ph
Externí odkaz:
https://doaj.org/article/35764ebdcfa54ab3bba7c112124d977b
Autor:
Chu-di Zhang, Li-hong Jiang, Xue Zhou, Yong-ping He, Ye Liu, Dong-ming Zhou, Yao Lv, Ben-qing Wu, Zheng-yan Zhao
Publikováno v:
Translational Oncology, Vol 39, Iss , Pp 101812- (2024)
Background: Malignancies with BRCA1/2 deficiencies are particularly sensitive to PARP inhibitors. Thus, combining PARP inhibitors with agents that impair DNA damage repair to treat BRCA1/2 wild-type PDAC could broaden the clinical use of these promis
Externí odkaz:
https://doaj.org/article/659d894b4a5e48ee9d39b18d38a42a5e
Autor:
Madhumanti Barman, Debabrata Dandasena, Akash Suresh, Vasundhra Bhandari, Sonam Kamble, Sakshi Singh, Madhusmita Subudhi, Paresh Sharma
Publikováno v:
Cell Communication and Signaling, Vol 21, Iss 1, Pp 1-15 (2023)
Abstract Background Bovine theileriosis caused by the eukaryotic parasite Theileria annulata is an economically important tick-borne disease. If it is not treated promptly, this lymphoproliferative disease has a significant fatality rate. Buparvaquon
Externí odkaz:
https://doaj.org/article/3fb62d09bc254745b357b99f50d6c361
Autor:
Yuwei Chen, Jun Wang
Publikováno v:
Applied Sciences, Vol 14, Iss 8, p 3186 (2024)
1-Deoxynojirimycin (DNJ) is a type of alkaloid that mainly exists in mulberry fruit and leaves. DNJ inhibits α-glucosidase, reduces the absorption of sugar, and suppresses after-meal hyperglycemia. It was reported that DNJ functions in attenuating c
Externí odkaz:
https://doaj.org/article/b77b4bfda43c477cb98b8d273b8602d0
Autor:
Hanna Hofmann, Alexandra Önder, Juliane Becker, Michael Gröger, Markus M. Müller, Fabian Zink, Barbara Stein, Peter Radermacher, Christiane Waller
Publikováno v:
Frontiers in Medicine, Vol 10 (2023)
IntroductionPost-COVID-19 fatigue is common after recovery from COVID-19. Excess formation of reactive oxygen species (ROS) leading to oxidative stress-related mitochondrial dysfunction is referred to as a cause of these chronic fatigue-like symptoms
Externí odkaz:
https://doaj.org/article/87f686b24f014600a20162c0c90d6c41