Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Oxalomalate"'
Autor:
Sung Hwan Kim, Hyunjin Kim, Hyeong Jun Ku, Jung Hyun Park, Hanvit Cha, Seoyoon Lee, Jin Hyup Lee, Jeen-Woo Park
Publikováno v:
Redox Biology, Vol 10, Iss C, Pp 211-220 (2016)
Clinical and experimental observations indicate a critical role for vascular endothelial growth factor (VEGF), secreted by the retinal pigment epithelium (RPE), in pathological angiogenesis and the development of choroidal neovascularization (CNV) in
Externí odkaz:
https://doaj.org/article/09b77ff4f9214ed8bd143924267158ce
Autor:
Edward M Haller, Kyle A. Bauckman, Nicholas Taran, Meera Nanjundan, Stephanie Rockfield, Abigail Ruiz-Rivera
Publikováno v:
Biochemical Journal
The role of iron in the development of cancer remains unclear. We previously reported that iron reduces cell survival in a Ras/mitogen-activated protein kinase (MAPK)-dependent manner in ovarian cells; however, the underlying downstream pathway leadi
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research. 1691(2-3):151-159
Ferritin is a ubiquitous protein required for intracellular iron storage; its biosynthesis is mainly regulated by iron-regulatory proteins (IRP1 and IRP2) at post-transcriptional level. This regulation prevents iron excess from promoting the formatio
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Rendiconti Lincei. 13:37-43
We investigated on cultured 3T3-L1 pre-adipocytes incubated with and withoutα-hydroxy-β-oxalosuccinic acid, shortly named oxalomalate (OMA), the rate of growth and differentiation together with fatty acids and protein synthesis and the variation of
Autor:
Michela Festa, Alfredo Ruffo
Publikováno v:
Rendiconti Lincei. 11:111-114
It has been investigated whether oxalomalate (OMA) the competitive inhibitor of cytosolic aconitase might extend its effect also on IRP-1, an iron regulatory protein, probably present in a commercial preparation of purified aconitase. The results sho
Publikováno v:
Rendiconti Lincei. 10:21-24
It has been investigatedin vitro the effect of oxalomalate (OMA) on the ferritin mRNA binding capacity of the bifunctional protein aconitase/IRP-1 contained in lysates of confluent cultures of 3T3-L1 fibroblasts. After short time of incubation with O
Autor:
Carlo Irace, Maria Assunta Bevilacqua, Carmen Maffettone, Rita Santamaria, Alfredo Colonna, Barbara Iovine
Publikováno v:
Biochimica et biophysica acta. 1763(8)
Ferritin gene expression is complex and is controlled at transcriptional level in response to a variety of stimuli such as hormones, cytokines and cAMP. Iron, hemin and several compounds, chemically different, also activate the transcription of the f