Potential therapeutic applications of microRNAs in cancer diagnosis and treatment: Sharpening a double-edged sword?

Autor: Mahasin, Abdel Rhman, Owira, Pmo

Publikováno v: European Journal of Pharmacology. 932:175210

Cancer is a leading cause of increased morbidity and mortality worldwide despite advancements in diagnosis and treatment. Lack of early detection and diagnosis of different cancers and adverse effects and toxicity associated with conventional cancer

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71950e4941674034ba329a37f303da63
https://doi.org/10.1016/j.ejphar.2022.175210

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The link between relative stability constant of DNA- and BSA-chromenopyrimidine complexes and cytotoxicity towards human breast cancer cells (MCF-7).

Autor: Zamisa SJ; School of Chemistry and Physics, University of KwaZulu-Natal Private Bag X54001 Durban 4000 South Africa owaga@ukzn.ac.za., Adeleke AA; School of Chemistry and Physics, University of KwaZulu-Natal Private Bag X54001 Durban 4000 South Africa owaga@ukzn.ac.za., Devnarain N; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Science, University of KwaZulu-Natal Private Bag X54001 Durban 4000 South Africa., Rhman MA; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Science, University of KwaZulu-Natal Private Bag X54001 Durban 4000 South Africa., Owira PMO; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Science, University of KwaZulu-Natal Private Bag X54001 Durban 4000 South Africa., Omondi B; School of Chemistry and Physics, University of KwaZulu-Natal Private Bag X54001 Durban 4000 South Africa owaga@ukzn.ac.za.

Publikováno v: RSC advances [RSC Adv] 2023 Jul 19; Vol. 13 (32), pp. 21820-21837. Date of Electronic Publication: 2023 Jul 19 (Print Publication: 2023).

Antidiabetic effects of Psidium x durbanensis Baijnath & Ramcharun ined. (Myrtaceae) leaf extract on streptozotocin-induced diabetes in rats.

Autor: Mbara KC; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, University of KwaZulu-Natal, P.O. Box X5401, Durban, South Africa., Rambharose S; Department of Physiological Sciences, Faculty of Science, Stellenbosch University, Private Bag X1 Matieland, Stellenbosch, 7602, South Africa., Baijnath H; Ward Herbarium, School of Life Sciences, University of KwaZulu-Natal, Durban, 4000, KwaZulu-Natal, South Africa., Nlooto M; Discipline of Pharmacy, School of Health Sciences, College of Health Sciences, University of KwaZulu-Natal, Westville Campus, Durban, 4001, South Africa; Department of Pharmaceutical Science, Healthcare Sciences, University of Limpopo, South Africa., Owira PMO; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, University of KwaZulu-Natal, P.O. Box X5401, Durban, South Africa. Electronic address: owirap@ukzn.ac.za.

Publikováno v: Journal of ethnopharmacology [J Ethnopharmacol] 2022 Oct 28; Vol. 297, pp. 115542. Date of Electronic Publication: 2022 Jul 14.

By reducing oxidative stress, naringenin mitigates hyperglycaemia-induced upregulation of hepatic nuclear factor erythroid 2-related factor 2 protein.

Autor: Kometsi L; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa., Govender K; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa., Mofo Mato EP; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa., Hurchund R; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa., Owira PMO; Molecular and Clinical Pharmacology Research Laboratory, Department of Pharmacology, Discipline of Pharmaceutical Sciences, School of Health Sciences, University of KwaZulu-Natal, Durban, South Africa.

Publikováno v: The Journal of pharmacy and pharmacology [J Pharm Pharmacol] 2020 Oct; Vol. 72 (10), pp. 1394-1404. Date of Electronic Publication: 2020 Jul 06.