Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Owens, RJ"'
Autor:
Buchanan, Cj, Gaunt, B, Harrison, Pj, Yang, Y, Liu, J, Khan, A, Giltrap, Am, Le Bas, A, Ward, Pn, Gupta, K, Dumoux, M, Tan, Tk, Schimaski, L, Daga, S, Picchiotti, N, Baldassarri, M, Benetti, E, Fallerini, C, Fava, F, Giliberti, A, Koukos, Pi, Davy, Mj, Lakshminarayanan, A, Xue, X, Papadakis, G, Deimel, Lp, Casablancas-Antràs, V, Claridge, Tdw, Bonvin, Amjj, Settentau, Qj, Furini, S, Gori, M, Huo, J, Owens, Rj, Schaffitzel, C, Berger, I, Renieri, A, GEN-COVID Multicenter Study, Naismith, Jh, Baldwin, Aj, Davis, Bg
Publikováno v:
Science, 377(6604), 1. American Association for the Advancement of Science
Berger-Schaffitzel, C H & Berger, I 2022, ' Pathogen-sugar interactions revealed by universal saturation transfer analysis ', Science, vol. 377, no. 6604 . https://doi.org/10.1126/science.abm3125
Science
Berger-Schaffitzel, C H & Berger, I 2022, ' Pathogen-sugar interactions revealed by universal saturation transfer analysis ', Science, vol. 377, no. 6604 . https://doi.org/10.1126/science.abm3125
Science
Many pathogens exploit host cell-surface glycans. However, precise analyses of glycan ligands binding with heavily modified pathogen proteins can be confounded by overlapping sugar signals and/or compounded with known experimental constraints. Univer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495263d9986e4c507c6361f37e4830a
https://ora.ox.ac.uk/objects/uuid:983bb274-46bb-4873-8119-d49f6684e908
https://ora.ox.ac.uk/objects/uuid:983bb274-46bb-4873-8119-d49f6684e908
Autor:
Hirunpattarasilp, C, James, G, Kwanthongdee, J, Freitas, F, Huo, J, Sethi, H, Kittler, JT, Owens, RJ, McCoy, LE, Attwell, D
The SARS-CoV-2 receptor, ACE2, is found on pericytes, contractile cells enwrapping capillaries that regulate brain, heart and kidney blood flow. ACE2 converts vasoconstricting angiotensin II into vasodilating angiotensin-(1-7). In brain slices from h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bb8c7edc7fa35c0de55c6c4048faf610
https://ora.ox.ac.uk/objects/uuid:61756878-ffb8-4c63-911b-c7438cd83245
https://ora.ox.ac.uk/objects/uuid:61756878-ffb8-4c63-911b-c7438cd83245
Autor:
Lanyon-Hogg, T, Masumoto, N, Bodakh, G, Konitsiotis, AD, Thinon, E, Rodgers, UR, Owens, RJ, Magee, AI, Tate, EW
Publikováno v:
Data in Brief, Vol 7, Iss, Pp 257-281 (2016)
In this data article we describe synthetic and characterisation data for four members of the 5-acyl-6,7-dihydrothieno[3,2-c]pyridine (termed “RU-SKI”) class of inhibitors of Hedgehog acyltransferase, including associated NMR spectra for final com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::0384df8f6a1c20a51dd4ac8492a7078c
https://doi.org/10.1016/j.dib.2016.02.012
https://doi.org/10.1016/j.dib.2016.02.012
Autor:
King, DJ, Turner, A, Farnsworth, AP, Adair, JR, Owens, RJ, Pedley, RB, Baldock, D, Proudfoot, KA, Lawson, AD, Beeley, NR
The construction and use of recombinant chimeric and later fully humanized (CDR-grafted) antibodies to tumor-associated antigens has reduced the immune response generated to these antibodies in clinical studies. However, their long circulating half-l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::62ab984ff9fe8b16827b8a9ff52b72b6
https://ora.ox.ac.uk/objects/uuid:499db092-6b7a-41e3-8b23-142e5c0db9ed
https://ora.ox.ac.uk/objects/uuid:499db092-6b7a-41e3-8b23-142e5c0db9ed
Autor:
Shi, J, Ghirlando, R, Beavil, RL, Beavil, AJ, Keown, MB, Young, RJ, Owens, RJ, Sutton, BJ, Gould, HJ
CD23/Fc epsilonRII, the low-affinity receptor for IgE, is a multifunctional protein of importance in blood cell development and the immune system. We have studied the interaction of CD23 with IgE in solution using hydrodynamic methods applied to reco
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8d586c887131fad4b578d89fe0f878bc
https://ora.ox.ac.uk/objects/uuid:5f2d6844-5a3e-4d84-9c4d-00a76d8822ac
https://ora.ox.ac.uk/objects/uuid:5f2d6844-5a3e-4d84-9c4d-00a76d8822ac
Autor:
Tiede, C, Tang, AA, Deacon, SE, Mandal, U, Nettleship, JE, Owen, RL, George, SE, Harrison, DJ, Owens, RJ, Tomlinson, DC, McPherson, MJ
We have designed a novel non-antibody scaffold protein, termed Adhiron, based on a phytocystatin consensus sequence. The Adhiron scaffold shows high thermal stability (Tm ca. 101°C), and is expressed well in Escherichia coli. We have determined the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::412d8f1ab871124cce996f6ae64987bf
Autor:
van Berkel, SS, Brem, J, Rydzik, AM, Salimraj, R, Cain, R, Verma, A, Owens, RJ, Fishwick, CWG, Spencer, J, Schofield, CJ
Metallo-β-lactamases (MBLs) are a growing threat to the use of almost all clinically used β-lactam antibiotics. The identification of broad-spectrum MBL inhibitors is hampered by the lack of a suitable screening platform, consisting of appropriate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::4bf46c9fc573214e5594c5e0062c5ab8
Autor:
Coutard, B, Gorbalenya, AE, Snijder, EJ, Leontovich, AM, Poupon, A, De Lamballerie, X, Charrel, R, Gould, EA, Gunther, S, Norder, H, Klempa, B, Bourhy, H, Rohayem, J, L'hermite, E, Nordlund, P, Stuart, DI, Owens, RJ, Grimes, JM, Tucker, PA, Bolognesi, M
Publikováno v:
Antiviral research
78 (2008): 37–46.
info:cnr-pdr/source/autori:Coutard, B; Gorbalenya, AE; Snijder, EJ; Leontovich, AM; Poupon, A; De Lamballerie, X; Charrel, R; Gould, EA; Gunther, S; Norder, H; Klempa, B; Bourhy, H; Rohayem, J; L'hermite, E; Nordlund, P; Stuart, DI; Owens, RJ; Grimes, JM; Tucker, PA; Bolognesi, M;/titolo:The VIZIER project: Preparedness against pathogenic RNA viruses/doi:/rivista:Antiviral research (Print)/anno:2008/pagina_da:37/pagina_a:46/intervallo_pagine:37–46/volume:78
78 (2008): 37–46.
info:cnr-pdr/source/autori:Coutard, B; Gorbalenya, AE; Snijder, EJ; Leontovich, AM; Poupon, A; De Lamballerie, X; Charrel, R; Gould, EA; Gunther, S; Norder, H; Klempa, B; Bourhy, H; Rohayem, J; L'hermite, E; Nordlund, P; Stuart, DI; Owens, RJ; Grimes, JM; Tucker, PA; Bolognesi, M;/titolo:The VIZIER project: Preparedness against pathogenic RNA viruses/doi:/rivista:Antiviral research (Print)/anno:2008/pagina_da:37/pagina_a:46/intervallo_pagine:37–46/volume:78
Life-threatening RNA viruses emerge regularly, and often in an unpredictable manner. Yet, the very few drugs available against known RNA viruses have sometimes required decades of research for development. Can we generate preparedness for outbreaks o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=cnr_________::2bf754cc20209b24c65662abf9e87357
https://publications.cnr.it/doc/3326
https://publications.cnr.it/doc/3326