Zobrazeno 1 - 10
of 46
pro vyhledávání: '"Owen W, Nadeau"'
Autor:
Ravneet Chhabra, Stephanie Rockfield, Jennifer Guergues, Owen W. Nadeau, Robert Hill, Stanley M. Stevens, Meera Nanjundan
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-25 (2021)
Abstract Malignant transformation of fallopian tube secretory epithelial cells (FTSECs) is a key contributing event to the development of high-grade serous ovarian carcinoma (HGSOC). Our recent findings implicate oncogenic transformative events in ch
Externí odkaz:
https://doaj.org/article/3cd9b0319f014bbca15071f2bb784312
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3358 (2019)
We describe a 7-year-old male with high functioning autism spectrum disorder (ASD) and maternally-inherited rare missense variant of Synaptotagmin-like protein 4 (SYTL4) gene (Xq22.1; c.835C>T; p.Arg279Cys) and an unknown missense variant of Transmem
Externí odkaz:
https://doaj.org/article/1d292fc2a1a44e76a09eeccd6523965e
Autor:
Dale Chaput, Stanley M. Stevens, Crystina L. Kriss, Sameer Varma, Nalvi Duro, Ashley E. Culver-Cochran, Owen W. Nadeau, Omar Chavez‐Chiang, Jennifer Guergues
Publikováno v:
Journal of mass spectrometry : JMSREFERENCES. 56(6)
Oxidative and nitrative stress have been implicated in the molecular mechanisms underlying a variety of biological processes and disease states including cancer, aging, cardiovascular disease, neurological disorders, diabetes, and alcohol-induced liv
Publikováno v:
Journal of Biological Chemistry. 293:7099-7107
The key regulatory enzymes of glycogenolysis are phosphorylase kinase, a hetero-oligomer with four different types of subunits, and glycogen phosphorylase, a homodimer. Both enzymes are activated by phosphorylation and small ligands, and both enzymes
Publikováno v:
Protein Science. 27:485-497
In the tightly regulated glycogenolysis cascade, the breakdown of glycogen to glucose-1-phosphate, phosphorylase kinase (PhK) plays a key role in regulating the activity of glycogen phosphorylase. PhK is a 1.3 MDa hexadecamer, with four copies each o
Autor:
Jianyi Yang, Mary Ashley Rimmer, Antonio Artigues, Yang Zhang, Owen W. Nadeau, Gerald M. Carlson
Publikováno v:
Protein Science. 27:472-484
Phosphorylase kinase (PhK), a 1.3 MDa regulatory enzyme complex in the glycogenolysis cascade, has four copies each of four subunits, (αβγδ)4 , and 325 kDa of unique sequence (the mass of an αβγδ protomer). The α, β and δ subunits are regu
Publikováno v:
Biochemistry. 54:7524-7530
In the six decades since its discovery, phosphorylase kinase (PhK) from rabbit skeletal muscle has usually been studied at 30 °C; in fact, not a single study has examined functions of PhK at a rabbit's body temperature, which is nearly 10 °C greate
Publikováno v:
Protein science : a publication of the Protein Society. 27(2)
In the tightly regulated glycogenolysis cascade, the breakdown of glycogen to glucose‐1‐phosphate, phosphorylase kinase (PhK) plays a key role in regulating the activity of glycogen phosphorylase. PhK is a 1.3 MDa hexadecamer, with four copies ea
Autor:
Mary Ashley, Rimmer, Owen W, Nadeau, Jianyi, Yang, Antonio, Artigues, Yang, Zhang, Gerald M, Carlson
Publikováno v:
Protein science : a publication of the Protein Society. 27(2)
Phosphorylase kinase (PhK), a 1.3 MDa regulatory enzyme complex in the glycogenolysis cascade, has four copies each of four subunits, (αβγδ)4, and 325 kDa of unique sequence (the mass of an αβγδ protomer). The α, β and δ subunits are regul
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 13
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3358 (2019)
Volume 20
Issue 13
International Journal of Molecular Sciences, Vol 20, Iss 13, p 3358 (2019)
We describe a 7-year-old male with high functioning autism spectrum disorder (ASD) and maternally-inherited rare missense variant of Synaptotagmin-like protein 4 (SYTL4) gene (Xq22.1
c.835C>
T
p.Arg279Cys) and an unknown missense var
c.835C>
T
p.Arg279Cys) and an unknown missense var