Zobrazeno 1 - 10
of 51
pro vyhledávání: '"Owen T. Jones"'
Autor:
Philip Robinson, Sarah Etheridge, Lele Song, Riddhi Shah, Elizabeth M Fitzgerald, Owen T Jones
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19802 (2011)
Voltage-gated calcium channels (Ca(v)) exist as heteromultimers comprising a pore-forming α(1) with accessory β and α(2)δ subunits which modify channel trafficking and function. We previously showed that α(2)δ-1 (and likely the other mammalian
Externí odkaz:
https://doaj.org/article/f991a0d4f321493990d505e89ad33394
Autor:
Lele Song, Sarah L. Etheridge, Owen T. Jones, Italo A. Espinoza-Fuenzalida, Elizabeth M. Fitzgerald
Publikováno v:
Current Molecular Pharmacology. 8:169-179
Voltage-gated calcium channels (Cav) and their associated proteins are pivotal signalling complexes in excitable cell physiology. In nerves and muscle, Cav tailor calcium influx to processes including neurotransmission, muscle contraction and gene ex
Autor:
Sarah L. Etheridge, Paul Armenise, Philip Robinson, Elizabeth M. Fitzgerald, Lele Song, Owen T. Jones
Publikováno v:
Cell Calcium. 48:183-194
Voltage-gated calcium channels (Ca(v)s) comprise a pore-forming α₁ with auxiliary α₂δ and β subunits which modulate Ca(v) function and surface expression. Ca(v)α₁ and α₂δ are present in signalling complexes termed lipid rafts but it is
Publikováno v:
Neuroscience Research. 67:245-249
The ability of l-3,4-dihydroxyphenylalanine (l-DOPA), l-DOPA-methyl ester and their major metabolites, dopamine, dihydroxyphenylacetic acid (DOPAC), homovanillic (HVA), 3-O-methyldopa and 3-methoxytyramine (3-MT) to bind to alpha(2) adrenergic and D1
Publikováno v:
Journal of Biological Chemistry. 283:30421-30432
The dynamic expression of voltage-gated potassium channels (Kvs) at the cell surface is a fundamental factor controlling membrane excitability. In exploring possible mechanisms controlling Kv surface expression, we identified a region in the extracel
Publikováno v:
Molecular Membrane Biology. 25:332-343
The last decade has witnessed an exponential increase in interest in one of the great mysteries of nerve cell biology: Specifically, how do neurons know where to place the ion channels that control their excitability? Many of the most important insig
Autor:
Alison M. Gurney, Alexei Verkhratsky, David A. Eisner, Shmuel Muallem, R. Maynard Case, Owen T. Jones
Publikováno v:
Cell Calcium. 42:345-350
Specific Ca(2+) homeostatic system appeared very early in the history of the cell, as a survival system preventing Ca(2+)-mediated cell damage. This homeostatic system produced a steep ( approximately 20,000 times) concentration gradient between extr
Autor:
Geula M. Bernstein, Owen T. Jones
Publikováno v:
Cell Calcium. 41:27-40
The contribution of voltage-gated calcium channels to excitable cell function depends, critically, upon the mechanisms that control their expression at the cell surface. While co-assembly of the pore forming alpha(1) and auxiliary beta subunits enhan
Publikováno v:
Acta Pharmacologica Sinica. 27:799-812
The pore-forming alpha subunits of voltage-gated calcium channels contain the essential biophysical machinery that underlies calcium influx in response to cell depolarization. In combination with requisite auxiliary subunits, these pore sub-units for
Autor:
Lesley E. Smart, Owen T. Jones, Antony M. Hooper, Lynda Ireland, Lester J. Wadhams, J. N. Oakley, Toby J. A. Bruce, J. L. Martin
Publikováno v:
Pest Management Science. 63:49-56
Field-trapping experiments with synthetic 2,7-nonadiyl dibutyrate, the female-produced sex pheromone of the orange wheat blossom midge, Sitodiplosis mosellana (Gehin), demonstrated that pheromone traps were highly attractive to males and caught very