Zobrazeno 1 - 10
of 125
pro vyhledávání: '"Owen T Jones"'
Autor:
Philip Robinson, Sarah Etheridge, Lele Song, Riddhi Shah, Elizabeth M Fitzgerald, Owen T Jones
Publikováno v:
PLoS ONE, Vol 6, Iss 6, p e19802 (2011)
Voltage-gated calcium channels (Ca(v)) exist as heteromultimers comprising a pore-forming α(1) with accessory β and α(2)δ subunits which modify channel trafficking and function. We previously showed that α(2)δ-1 (and likely the other mammalian
Externí odkaz:
https://doaj.org/article/f991a0d4f321493990d505e89ad33394
Autor:
Lele Song, Sarah L. Etheridge, Owen T. Jones, Italo A. Espinoza-Fuenzalida, Elizabeth M. Fitzgerald
Publikováno v:
Current Molecular Pharmacology. 8:169-179
Voltage-gated calcium channels (Cav) and their associated proteins are pivotal signalling complexes in excitable cell physiology. In nerves and muscle, Cav tailor calcium influx to processes including neurotransmission, muscle contraction and gene ex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c7539549521d03fae6c599250954071
https://doi.org/10.2174/1874467208666150507104555
https://doi.org/10.2174/1874467208666150507104555
Autor:
Sarah L. Etheridge, Paul Armenise, Philip Robinson, Elizabeth M. Fitzgerald, Lele Song, Owen T. Jones
Publikováno v:
Cell Calcium. 48:183-194
Voltage-gated calcium channels (Ca(v)s) comprise a pore-forming α₁ with auxiliary α₂δ and β subunits which modulate Ca(v) function and surface expression. Ca(v)α₁ and α₂δ are present in signalling complexes termed lipid rafts but it is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e212784fa900b8f671f11967256dd26
https://doi.org/10.1016/j.ceca.2010.08.006
https://doi.org/10.1016/j.ceca.2010.08.006
Publikováno v:
Neuroscience Research. 67:245-249
The ability of l-3,4-dihydroxyphenylalanine (l-DOPA), l-DOPA-methyl ester and their major metabolites, dopamine, dihydroxyphenylacetic acid (DOPAC), homovanillic (HVA), 3-O-methyldopa and 3-methoxytyramine (3-MT) to bind to alpha(2) adrenergic and D1
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b86f00d9bb940419614a3968e9d8a4d
https://doi.org/10.1016/j.neures.2010.03.008
https://doi.org/10.1016/j.neures.2010.03.008
Publikováno v:
Journal of Biological Chemistry. 283:30421-30432
The dynamic expression of voltage-gated potassium channels (Kvs) at the cell surface is a fundamental factor controlling membrane excitability. In exploring possible mechanisms controlling Kv surface expression, we identified a region in the extracel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1425745d4ea4e145a7707e3e336b3eec
https://doi.org/10.1074/jbc.m708921200
https://doi.org/10.1074/jbc.m708921200
Publikováno v:
Molecular Membrane Biology. 25:332-343
The last decade has witnessed an exponential increase in interest in one of the great mysteries of nerve cell biology: Specifically, how do neurons know where to place the ion channels that control their excitability? Many of the most important insig
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5eaa85a06941948875e05b6486470e0
https://doi.org/10.1080/09687680801992470
https://doi.org/10.1080/09687680801992470
Autor:
Alison M. Gurney, Alexei Verkhratsky, David A. Eisner, Shmuel Muallem, R. Maynard Case, Owen T. Jones
Publikováno v:
Cell Calcium. 42:345-350
Specific Ca(2+) homeostatic system appeared very early in the history of the cell, as a survival system preventing Ca(2+)-mediated cell damage. This homeostatic system produced a steep ( approximately 20,000 times) concentration gradient between extr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d2309f130d36784197441b593ffefdff
https://doi.org/10.1016/j.ceca.2007.05.001
https://doi.org/10.1016/j.ceca.2007.05.001
Autor:
Geula M. Bernstein, Owen T. Jones
Publikováno v:
Cell Calcium. 41:27-40
The contribution of voltage-gated calcium channels to excitable cell function depends, critically, upon the mechanisms that control their expression at the cell surface. While co-assembly of the pore forming alpha(1) and auxiliary beta subunits enhan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0169af2e5379a7155f6b343505d9c97b
https://doi.org/10.1016/j.ceca.2006.04.010
https://doi.org/10.1016/j.ceca.2006.04.010
Publikováno v:
Acta Pharmacologica Sinica. 27:799-812
The pore-forming alpha subunits of voltage-gated calcium channels contain the essential biophysical machinery that underlies calcium influx in response to cell depolarization. In combination with requisite auxiliary subunits, these pore sub-units for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ec33de2f76b42493f86d003a02e14806
https://doi.org/10.1111/j.1745-7254.2006.00394.x
https://doi.org/10.1111/j.1745-7254.2006.00394.x
Autor:
Lesley E. Smart, Owen T. Jones, Antony M. Hooper, Lynda Ireland, Lester J. Wadhams, J. N. Oakley, Toby J. A. Bruce, J. L. Martin
Publikováno v:
Pest Management Science. 63:49-56
Field-trapping experiments with synthetic 2,7-nonadiyl dibutyrate, the female-produced sex pheromone of the orange wheat blossom midge, Sitodiplosis mosellana (Gehin), demonstrated that pheromone traps were highly attractive to males and caught very
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::442ac65aac7de7f48b7268e4754ba74d
https://doi.org/10.1002/ps.1307
https://doi.org/10.1002/ps.1307