Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Owen P Leiser"'
Autor:
Owen P Leiser, Deanna L Auberry, Erica Bakker, Will Chrisler, Kristin Engbrecht, Heather Engelmann, Sarah Fansler, Vincent Gerbasi, Joshua Hansen, Chelsea Hutchinson, Janine Hutchison, Mary J Lancaster, Kathleen Lawrence, Angela Melville, Jennifer Mobberley, Isabelle O'Bryon, Kristie L Oxford, Tessa Oxford, Shelby Phillips, Kabrena E Rodda, James A Sanford, Athena Schepmoes, Brian E Staley, Kelcey Terrell, Kristin Victry, Cynthia Warner, Kristin M Omberg
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0285042 (2023)
In 2020, the Department of Energy established the National Virtual Biotechnology Laboratory (NVBL) to address key challenges associated with COVID-19. As part of that effort, Pacific Northwest National Laboratory (PNNL) established a capability to co
Externí odkaz:
https://doaj.org/article/e0ec10df0e7b47ff951c40ec9c20b47b
Autor:
Michael H Norris, Diansy Zincke, Owen P Leiser, Helen Kreuzer, Ted L Hadfied, Jason K Blackburn
Publikováno v:
PLoS ONE, Vol 15, Iss 1, p e0228270 (2020)
Bacillus anthracis is the causative agent of anthrax in animals and humans. The organism lies in a dormant state in the soil until introduced into an animal via, ingestion, cutaneous inoculation or inhalation. Once in the host, spores germinate into
Externí odkaz:
https://doaj.org/article/3f308ae5a85048c3b8872a11895cee60
Autor:
Owen P Leiser, Jason K Blackburn, Ted L Hadfield, Helen W Kreuzer, David S Wunschel, Cindy J Bruckner-Lea
Publikováno v:
PLoS ONE, Vol 13, Iss 12, p e0209120 (2018)
The spore forming pathogen Bacillus anthracis is the etiologic agent of anthrax in humans and animals. It cycles through infected hosts as vegetative cells and is eventually introduced into the environment where it generates an endospore resistant to
Externí odkaz:
https://doaj.org/article/7cabc7ab5c374a54b0b180061e8cbab4
Autor:
Eric D Merkley, Landon H Sego, Andy Lin, Owen P Leiser, Brooke L Deatherage Kaiser, Joshua N Adkins, Paul S Keim, David M Wagner, Helen W Kreuzer
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0183478 (2017)
The rapid pace of bacterial evolution enables organisms to adapt to the laboratory environment with repeated passage and thus diverge from naturally-occurring environmental ("wild") strains. Distinguishing wild and laboratory strains is clearly impor
Externí odkaz:
https://doaj.org/article/441b2ae267a4403ba0849c31708dd829
Autor:
Owen P Leiser, Eric D Merkley, Brian H Clowers, Brooke L Deatherage Kaiser, Andy Lin, Janine R Hutchison, Angela M Melville, David M Wagner, Paul S Keim, Jeffrey T Foster, Helen W Kreuzer
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0142997 (2015)
The bacterial pathogen Yersinia pestis, the cause of plague in humans and animals, normally has a sylvatic lifestyle, cycling between fleas and mammals. In contrast, laboratory-grown Y. pestis experiences a more constant environment and conditions th
Externí odkaz:
https://doaj.org/article/4d9aa4317b52434ca91822c8b33e7eb5
Autor:
Gerda Saxer, Michael D Krepps, Eric D Merkley, Charles Ansong, Brooke L Deatherage Kaiser, Marie-Thérèse Valovska, Nikola Ristic, Ping T Yeh, Vittal P Prakash, Owen P Leiser, Luay Nakhleh, Henry S Gibbons, Helen W Kreuzer, Yousif Shamoo
Publikováno v:
PLoS Genetics, Vol 10, Iss 12, p e1004872 (2014)
Adaptation to ecologically complex environments can provide insights into the evolutionary dynamics and functional constraints encountered by organisms during natural selection. Adaptation to a new environment with abundant and varied resources can b
Externí odkaz:
https://doaj.org/article/d24d9e61ba574f4fad634eee1b332b09
Publikováno v:
PLoS ONE, Vol 7, Iss 3, p e33979 (2012)
RseA sequesters RpoE (σ(E)) to the inner membrane of Escherichia coli when envelope stress is low. Elevated envelope stress triggers RseA cleavage by the sequential action of two membrane proteases, DegS and RseP, releasing σ(E) to activate an enve
Externí odkaz:
https://doaj.org/article/2eefae5280fd4c738e208fbed8a3d145
Publikováno v:
Pathogens, Vol 10, Iss 11, p 1497 (2021)
As of 2021, the biothreat policy and research communities organize their efforts around lists of priority agents, which elides consideration of novel pathogens and biotoxins. For example, the Select Agents and Toxins list is composed of agents that h
Externí odkaz:
https://doaj.org/article/194b7ddd01d94df2a72cd3a108d38336
Publikováno v:
Pathogens
Pathogens, Vol 10, Iss 1497, p 1497 (2021)
Pathogens, Vol 10, Iss 1497, p 1497 (2021)
As of 2021, the biothreat policy and research communities organize their efforts around lists of priority agents, which elides consideration of novel pathogens and biotoxins. For example, the Select Agents and Toxins list is composed of agents that h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c33d03f81e4e9e8165e33b0d894f65a
http://europepmc.org/articles/PMC8623450
http://europepmc.org/articles/PMC8623450
Publikováno v:
Journal of Bacteriology. 201
In Escherichia coli, the periplasmic protease DegP plays a critical role in degrading misfolded outer membrane proteins (OMPs). Consequently, mutants lacking DegP display a temperature-sensitive growth defect, presumably due to the toxic accumulation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ded0677b1d53d023c5f278df6cfd738
https://doi.org/10.1128/jb.00742-18
https://doi.org/10.1128/jb.00742-18