Zobrazeno 1 - 10
of 252
pro vyhledávání: '"Owen M Wolkowitz"'
Autor:
Synthia H Mellon, F Saverio Bersani, Daniel Lindqvist, Rasha Hammamieh, Duncan Donohue, Kelsey Dean, Marti Jett, Rachel Yehuda, Janine Flory, Victor I Reus, Linda M Bierer, Iouri Makotkine, Duna Abu Amara, Clare Henn Haase, Michelle Coy, Francis J Doyle, Charles Marmar, Owen M Wolkowitz
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213839 (2019)
Posttraumatic stress disorder (PTSD) is associated with impaired major domains of psychology and behavior. Individuals with PTSD also have increased co-morbidity with several serious medical conditions, including autoimmune diseases, cardiovascular d
Externí odkaz:
https://doaj.org/article/7a92b8e5847042428eb3305e3034fc25
Autor:
Zachary N. Blalock, Gwyneth W. Y Wu, Daniel Lindqvist, Caroline Trumpff, Janine D. Flory, Jue Lin, Victor I. Reus, Ryan Rampersaud, Rasha Hammamieh, Aarti Gautam, SBPBC, Francis J. Doyle, Charles R. Marmar, Marti Jett, Rachel Yehuda, Owen M. Wolkowitz, Synthia H. Mellon
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a biomarker of cellular injury or cellular stress and is a potential novel biomarker of psychological stress and of various brain, somatic, and psychiatric disorders. No studies have yet
Externí odkaz:
https://doaj.org/article/462b504a442545f2add418e35eab0665
Autor:
Owen M Wolkowitz, Synthia H Mellon, Elissa S Epel, Jue Lin, Firdaus S Dhabhar, Yali Su, Victor I Reus, Rebecca Rosser, Heather M Burke, Eve Kupferman, Mariana Compagnone, J Craig Nelson, Elizabeth H Blackburn
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e17837 (2011)
Depression is associated with an unusually high rate of aging-related illnesses and early mortality. One aspect of "accelerated aging" in depression may be shortened leukocyte telomeres. When telomeres critically shorten, as often occurs with repeate
Externí odkaz:
https://doaj.org/article/0a688fa0a230445fb4327c5e33cc4443
Autor:
Ryan Rampersaud, Gwyneth W. Y. Wu, Victor I. Reus, Jue Lin, Elizabeth H. Blackburn, Elissa S. Epel, Christina M. Hough, Synthia H. Mellon, Owen M. Wolkowitz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Telomere length (TL) is a marker of biological aging, and shorter telomeres have been associated with several medical and psychiatric disorders, including cardiometabolic dysregulation and Major Depressive Disorder (MDD). In addition, studie
Externí odkaz:
https://doaj.org/article/eced414471ba40eebb992e5b4b44aa9b
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The notion of “biological aging” as distinct from chronological aging has been of increasing interest in psychiatry, and many studies have explored associations of stress and psychiatric illness with accelerated biological aging. The “
Externí odkaz:
https://doaj.org/article/c860e605fdab45cc9bd8b70607b3e15a
Autor:
Edward J. Goetzl, Owen M. Wolkowitz, Laura Goetzl, Victor I. Reus, Dimitrios Kapogiannis, George R. Heninger, Synthia H. Mellon, Vinod H. Srihari
Publikováno v:
Molecular psychiatry, vol 26, iss 12
To characterize neuronal mitochondrial abnormalities in major depressive disorder (MDD), functional mitochondrial proteins (MPs) extracted from enriched plasma neuron-derived extracellular vesicles (NDEVs) of MDD participants (n = 20) were quantified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe86f87fddccdb13af17af6796732c87
https://doi.org/10.1038/s41380-021-01268-x
https://doi.org/10.1038/s41380-021-01268-x
Autor:
Seid Muhie, Aarti Gautam, Ruoting Yang, Burook Misganaw, Bernie J. Daigle, Synthia H. Mellon, Janine D. Flory, Duna Abu-Amara, Inyoul Lee, Kai Wang, Ryan Rampersaud, Leroy Hood, Rachel Yehuda, Charles R. Marmar, Owen M. Wolkowitz, Kerry J. Ressler, Francis J. Doyle, Rasha Hammamieh, Marti Jett
Publikováno v:
Cell Reports Medicine. 4:101045
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0307c9b5baa4bf345ff190f8b4fbc0b2
https://doi.org/10.1016/j.xcrm.2023.101045
https://doi.org/10.1016/j.xcrm.2023.101045
Autor:
Kai Xia, Elissa S. Epel, Jake D. Oxendine, David R. Rubinow, Aric A. Prather, Anthony S. Zannas, Jue Lin, Helena Palma-Gudiel, Jerry Guintivano, Owen M. Wolkowitz
Publikováno v:
Brain Behav Immun
Hypothalamic-pituitary-adrenal (HPA) axis dysregulation has been associated with altered immune function, but the underlying molecular mechanisms are unclear. Epigenetic processes, including DNA methylation, respond to the glucocorticoid end-products
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4f043951771280f09186c412fc69998f
https://doi.org/10.1016/j.bbi.2020.11.027
https://doi.org/10.1016/j.bbi.2020.11.027
Autor:
Burook Misganaw, Marti Jett, Rasha Hammamieh, Eugene M. Laska, Carole Siegel, Synthia H. Mellon, Francis J. Doyle, Kerry J. Ressler, Esther M. Blessing, Amit Etkin, Charles R. Marmar, Katharina Schultebraucks, Owen M. Wolkowitz, Aarti Gautam, Meng Qian, Duna Abu-Amara, Guia Guffanti, Kelsey R. Dean
Publikováno v:
Molecular Psychiatry
Active-duty Army personnel can be exposed to traumatic warzone events and are at increased risk for developing post-traumatic stress disorder (PTSD) compared with the general population. PTSD is associated with high individual and societal costs, but
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d72dc3aaab00e1ced34b2d40d73d421c
https://doi.org/10.1038/s41380-020-0789-2
https://doi.org/10.1038/s41380-020-0789-2
Autor:
F. Saverio Bersani, Victor I. Reus, Christina M. Hough, Synthia H. Mellon, Elissa S. Epel, Alexandra E. Morford, Owen M. Wolkowitz, Daniel Lindqvist
Publikováno v:
Psychological Medicine. 51:2117-2125
BackgroundMajor depressive disorder (MDD) is associated with increased allostatic load (AL; a measure of physiological costs of repeated/chronic stress-responding) and metabolic dysregulation (MetD; a measure of metabolic health and precursor to many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7374bf8dee10385edc1617ae37f1d16c
https://doi.org/10.1017/s0033291720000896
https://doi.org/10.1017/s0033291720000896