Zobrazeno 1 - 10
of 268
pro vyhledávání: '"Owen M, Wolkowitz"'
Autor:
Zachary N. Blalock, Gwyneth W. Y Wu, Daniel Lindqvist, Caroline Trumpff, Janine D. Flory, Jue Lin, Victor I. Reus, Ryan Rampersaud, Rasha Hammamieh, Aarti Gautam, SBPBC, Francis J. Doyle, Charles R. Marmar, Marti Jett, Rachel Yehuda, Owen M. Wolkowitz, Synthia H. Mellon
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Circulating cell-free mitochondrial DNA (ccf-mtDNA) is a biomarker of cellular injury or cellular stress and is a potential novel biomarker of psychological stress and of various brain, somatic, and psychiatric disorders. No studies have yet
Externí odkaz:
https://doaj.org/article/462b504a442545f2add418e35eab0665
Autor:
Ryan Rampersaud, Gwyneth W. Y. Wu, Victor I. Reus, Jue Lin, Elizabeth H. Blackburn, Elissa S. Epel, Christina M. Hough, Synthia H. Mellon, Owen M. Wolkowitz
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-14 (2023)
Abstract Telomere length (TL) is a marker of biological aging, and shorter telomeres have been associated with several medical and psychiatric disorders, including cardiometabolic dysregulation and Major Depressive Disorder (MDD). In addition, studie
Externí odkaz:
https://doaj.org/article/eced414471ba40eebb992e5b4b44aa9b
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The notion of “biological aging” as distinct from chronological aging has been of increasing interest in psychiatry, and many studies have explored associations of stress and psychiatric illness with accelerated biological aging. The “
Externí odkaz:
https://doaj.org/article/c860e605fdab45cc9bd8b70607b3e15a
Autor:
Ryan Rampersaud, Ekaterina Protsenko, Ruoting Yang, Victor Reus, Rasha Hammamieh, Gwyneth W. Y. Wu, Elissa Epel, Marti Jett, Aarti Gautam, Synthia H. Mellon, Owen M. Wolkowitz
Publikováno v:
Translational Psychiatry, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Adverse childhood experiences have been consistently linked with physical and mental health disorders in adulthood that may be mediated, in part, via the effects of such exposures on biological aging. Using recently developed “epigenetic c
Externí odkaz:
https://doaj.org/article/f221bc9ea6514ef5816e1a754594afdb
Autor:
Johan Fernström, Synthia H. Mellon, Marlon A. McGill, Martin Picard, Victor I. Reus, Christina M. Hough, Jue Lin, Elissa S. Epel, Owen M. Wolkowitz, Daniel Lindqvist
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-7 (2021)
Abstract Mitochondrial dysfunction has been implicated in major depressive disorder (MDD). A measure of mitochondrial respiratory chain (RC) enzymatic activity—the Mitochondrial Health Index (MHI)—has previously been found to correlate with stres
Externí odkaz:
https://doaj.org/article/bb5e5046f7e5489088c9d6125ed82ea3
Autor:
Ekaterina Protsenko, Ruoting Yang, Brent Nier, Victor Reus, Rasha Hammamieh, Ryan Rampersaud, Gwyneth W. Y. Wu, Christina M. Hough, Elissa Epel, Aric A. Prather, Marti Jett, Aarti Gautam, Synthia H. Mellon, Owen M. Wolkowitz
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Major depressive disorder (MDD) is associated with premature mortality and is an independent risk factor for a broad range of diseases, especially those associated with aging, such as cardiovascular disease, diabetes, and Alzheimer’s disea
Externí odkaz:
https://doaj.org/article/1ed1f36ac858446c87cd14a337d98223
Autor:
Carole E. Siegel, Eugene M. Laska, Ziqiang Lin, Mu Xu, Duna Abu-Amara, Michelle K. Jeffers, Meng Qian, Nicholas Milton, Janine D. Flory, Rasha Hammamieh, Bernie J. Daigle, Aarti Gautam, Kelsey R. Dean, Victor I. Reus, Owen M. Wolkowitz, Synthia H. Mellon, Kerry J. Ressler, Rachel Yehuda, Kai Wang, Leroy Hood, Francis J. Doyle, Marti Jett, Charles R. Marmar
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-12 (2021)
Abstract We sought to find clinical subtypes of posttraumatic stress disorder (PTSD) in veterans 6–10 years post-trauma exposure based on current symptom assessments and to examine whether blood biomarkers could differentiate them. Samples were mal
Externí odkaz:
https://doaj.org/article/e49caa92c9774a64b4ce6cfdf977ed9d
Autor:
Synthia H Mellon, F Saverio Bersani, Daniel Lindqvist, Rasha Hammamieh, Duncan Donohue, Kelsey Dean, Marti Jett, Rachel Yehuda, Janine Flory, Victor I Reus, Linda M Bierer, Iouri Makotkine, Duna Abu Amara, Clare Henn Haase, Michelle Coy, Francis J Doyle, Charles Marmar, Owen M Wolkowitz
Publikováno v:
PLoS ONE, Vol 14, Iss 3, p e0213839 (2019)
Posttraumatic stress disorder (PTSD) is associated with impaired major domains of psychology and behavior. Individuals with PTSD also have increased co-morbidity with several serious medical conditions, including autoimmune diseases, cardiovascular d
Externí odkaz:
https://doaj.org/article/7a92b8e5847042428eb3305e3034fc25
Autor:
Edward J. Goetzl, Owen M. Wolkowitz, Laura Goetzl, Victor I. Reus, Dimitrios Kapogiannis, George R. Heninger, Synthia H. Mellon, Vinod H. Srihari
Publikováno v:
Molecular psychiatry, vol 26, iss 12
To characterize neuronal mitochondrial abnormalities in major depressive disorder (MDD), functional mitochondrial proteins (MPs) extracted from enriched plasma neuron-derived extracellular vesicles (NDEVs) of MDD participants (n = 20) were quantified
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe86f87fddccdb13af17af6796732c87
https://doi.org/10.1038/s41380-021-01268-x
https://doi.org/10.1038/s41380-021-01268-x
Autor:
Seid Muhie, Aarti Gautam, Ruoting Yang, Burook Misganaw, Bernie J. Daigle, Synthia H. Mellon, Janine D. Flory, Duna Abu-Amara, Inyoul Lee, Kai Wang, Ryan Rampersaud, Leroy Hood, Rachel Yehuda, Charles R. Marmar, Owen M. Wolkowitz, Kerry J. Ressler, Francis J. Doyle, Rasha Hammamieh, Marti Jett
Publikováno v:
Cell Reports Medicine. 4:101045
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0307c9b5baa4bf345ff190f8b4fbc0b2
https://doi.org/10.1016/j.xcrm.2023.101045
https://doi.org/10.1016/j.xcrm.2023.101045