Zobrazeno 1 - 10
of 84
pro vyhledávání: '"Owen M, McDougal"'
Publikováno v:
Nutraceuticals, Vol 3, Iss 3, Pp 481-488 (2023)
In the United States (US), tianeptine is sold as a dietary supplement under the trade name Tianaa™. Tianeptine is a synthetic drug prescribed by physicians as an antidepressant in parts of Europe, Asia and South America. The drug is not permitted f
Externí odkaz:
https://doaj.org/article/d27b69e819964cca965c10792098239b
Autor:
Owen M. McDougal
Publikováno v:
AIMS Molecular Science, Vol 11, Iss 1, Pp 61-62 (2024)
Externí odkaz:
https://doaj.org/article/ce093a339d3c45c4806e1ad20912bec7
Autor:
Habeeb Abolaji Babatunde, Joseph Collins, Rianat Lukman, Rose Saxton, Timothy Andersen, Owen M. McDougal
Publikováno v:
Foods, Vol 13, Iss 1, p 166 (2024)
Protein content variation in milk can impact the quality and consistency of dairy products, necessitating access to in-line real time monitoring. Here, we present a chemometric approach for the qualitative and quantitative monitoring of β-lactoglobu
Externí odkaz:
https://doaj.org/article/72137f2ddc22440f97dbc1e431a96d60
Autor:
Madison L. Dirks, Owen M. McDougal
Publikováno v:
Pharmaceuticals, Vol 17, Iss 1, p 123 (2024)
Veratrum californicum contains steroidal alkaloids that function as inhibitors of hedgehog (Hh) signaling, a pathway involved in the growth and differentiation of cells and normal tissue development. This same Hh pathway is abnormally active for cell
Externí odkaz:
https://doaj.org/article/76d1402f503445c3917f94dd45c9a33a
Autor:
Jared T. Seale, Owen M. McDougal
Publikováno v:
Molecules, Vol 27, Iss 16, p 5349 (2022)
Plants of the Veratrum genus have been used throughout history for their emetic properties, rheumatism, and for the treatment of high blood pressure. However, inadvertent consumption of these plants, which resemble wild ramps, induces life-threatenin
Externí odkaz:
https://doaj.org/article/4dbd1b3e59a244c9bcf941775b8d35a1
Publikováno v:
BMC Bioinformatics, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Conventional de novo drug design is costly and time consuming, making it accessible to only the best resourced research organizations. An emergent approach to new drug development is drug repurposing, in which compounds that have
Externí odkaz:
https://doaj.org/article/45ba5aa17c5d41298f9ee12873d3c712
Publikováno v:
Molecules, Vol 26, Iss 19, p 5934 (2021)
Veratrum spp. grow throughout the world and are especially prevalent in high mountain meadows of North America. All parts of Veratrum plants have been used for the treatment of ailments including injuries, hypertension, and rheumatic pain since as fa
Externí odkaz:
https://doaj.org/article/8cf758334d91451e97245aac17af52c9
Autor:
Mark M. Skinner, Jared T. Seale, Maranda S. Cantrell, Joseph M. Collins, Matthew W. Turner, Owen M. McDougal
Publikováno v:
Foods, Vol 10, Iss 9, p 2038 (2021)
The purpose of this experimental review was to detect acrylamide in French fries using methods most adaptable to the food process industry for quality control assessment of products. French fries were prepared at different cook times using the same f
Externí odkaz:
https://doaj.org/article/193fc3e8d9624541836e3fbd54319169
Autor:
Decha Pinkaew, Abhijnan Chattopadhyay, Matthew D. King, Preedakorn Chunhacha, Zhihe Liu, Heather L. Stevenson, Yanjie Chen, Patuma Sinthujaroen, Owen M. McDougal, Ken Fujise
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-16 (2017)
IRE1α is an ER stress sensor, whose activity induces apoptosis. Here, the authors report that fortilin, a pro-survival factor, with yet unknown roles in ER stress, interacts with active IRE1α, inhibits both its kinase end RNase activities, and prot
Externí odkaz:
https://doaj.org/article/41562ffacfaf46d09359e93528290463
Autor:
Maranda S. Cantrell, Alejandro Soto-Avellaneda, Jackson D. Wall, Aaron D. Ajeti, Brad E. Morrison, Lisa R. Warner, Owen M. McDougal
Publikováno v:
Pharmaceuticals, Vol 14, Iss 6, p 573 (2021)
Drug development is a complicated, slow and expensive process with high failure rates. One strategy to mitigate these factors is to recycle existing drugs with viable safety profiles and have gained Food and Drug Administration approval following ext
Externí odkaz:
https://doaj.org/article/5b6b3721578d4944990252897d2ced0e