Zobrazeno 1 - 10
of 182
pro vyhledávání: '"Owen L. Woodman"'
Autor:
Jasmin Chendi Li, Anida Velagic, Cheng Xue Qin, Mandy Li, Chen Huei Leo, Barbara K. Kemp-Harper, Rebecca H. Ritchie, Owen L. Woodman
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
Introduction:Endothelial dysfunction is a major risk factor for several of the vascular complications of diabetes, including ischemic stroke. Nitroxyl (HNO), the one electron reduced and protonated form of nitric oxide (NO•), is resistant to scaven
Externí odkaz:
https://doaj.org/article/00f50aad06064c38b7a63a4ffc1a2c6e
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Non-alcoholic steatohepatitis (NASH) develops from non-alcoholic fatty liver disease (NAFLD). Currently, around 25% of the population is estimated to have NAFLD, and 25% of NAFLD patients are estimated to have NASH. NASH is typically characterized by
Externí odkaz:
https://doaj.org/article/2dc08ed0b09742598ac9467466fe05ab
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/4a617c44631742f3a19457a10a00d468
Autor:
Anida Velagic, Chengxue Qin, Owen L. Woodman, John D. Horowitz, Rebecca H. Ritchie, Barbara K. Kemp-Harper
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Diabetes is associated with an increased mortality risk due to cardiovascular complications. Hyperglycemia-induced oxidative stress underlies these complications, leading to an impairment in endogenous nitric oxide (NO•) generation, together with r
Externí odkaz:
https://doaj.org/article/c32c8c84718c4c9aacd2537124f3b443
Autor:
Saher F. Ali, Owen L. Woodman
Publikováno v:
Frontiers in Physiology, Vol 10 (2019)
We aimed to determine whether tocomin, an extract from palm oil that has a high tocotrienol content, was able to prevent diabetes-induced endothelial dysfunction. To induce type 1 diabetes streptozotocin (50 mg/kg) was injected into the tail vein of
Externí odkaz:
https://doaj.org/article/075c2a05c62e410996dce6e6cc6d5a8d
Autor:
Anida Velagic, Mandy Li, Minh Deo, Jasmin Chendi Li, Helen Kiriazis, Daniel G. Donner, Dovile Anderson, Miles J. De Blasio, Owen L. Woodman, Barbara K. Kemp-Harper, Cheng Xue Qin, Rebecca H. Ritchie
Publikováno v:
American journal of physiology. Heart and circulatory physiology.
Left ventricular (LV) dysfunction is an early, clinically detectable sign of cardiomyopathy in type 2 diabetes mellitus (T2DM) that precedes the development of symptomatic heart failure. Pre-clinical models of diabetic cardiomyopathy are essential to
Autor:
Maria Jelinic, Kristy L. Jackson, Kelly O'Sullivan, Jaideep Singh, Thomas Giddy, Minh Deo, Laura J. Parry, Rebecca H. Ritchie, Owen L. Woodman, Geoffrey A. Head, Chen Huei Leo, Cheng Xue Qin
Publikováno v:
Life Sciences. 320:121542
Autor:
Jaideep Singh, Kristy L Jackson, Audrey Gumanti, Haoyun Fang, Owen L Woodman, Rebecca H Ritchie, David Greening, Geoffrey A Head, Chengxue Qin
Publikováno v:
Journal of Hypertension. 41:e267-e268
Autor:
Anida Velagic, Jasmin Chendi Li, Cheng Xue Qin, Mandy Li, Minh Deo, Sarah A. Marshall, Dovile Anderson, Owen L. Woodman, John D. Horowitz, Barbara K. Kemp‐Harper, Rebecca H. Ritchie
Publikováno v:
Br J Pharmacol
The risk of fatal cardiovascular events is increased in patients with type 2 diabetes mellitus (T2DM). A major contributor to poor prognosis is impaired nitric oxide (NO•) signalling at the level of tissue responsiveness, termed NO• resistance. T
Autor:
Eoin P. Brennan, Owen L. Woodman, Rebecca H. Ritchie, Ting Fu, Muthukumar Mohan, Phillip Kantharidis, Catherine Godson, Chengxue Qin
Publikováno v:
ACS Pharmacology & Translational Science. 3:43-55
Several studies have shown that failure to resolve inflammation may contribute to the progression of many chronic inflammatory disorders. It has been suggested targeting the resolution of inflammat...