Zobrazeno 1 - 10
of 80
pro vyhledávání: '"Owen B Spiller"'
Autor:
Elizabeth Agyare, Joseph Elikem Efui Acolatse, Mavis Puopelle Dakorah, George Akafity, Victoria J Chalker, Owen B Spiller, Kristan Alexander Schneider, Saviour Yevutsey, Nana Benyin Aidoo, Sophia Blankson, Frederick Mensah-Acheampong, Robert Incoom, Amanj Kurdi, Brian Godman, Eric Kofi Ngyedu
Publikováno v:
PLoS ONE, Vol 19, Iss 1, p e0297626 (2024)
IntroductionAntimicrobial resistance (AMR) is a global threat that necessitates coordinated strategies to improve antibiotic prescribing and reduce AMR. A key activity is ascertaining current prescribing patterns in hospitals to identify targets for
Externí odkaz:
https://doaj.org/article/b81a0806c1c44d4ea113570fb13e2133
Autor:
Monique G M Willems, Matthew W Kemp, Laura A Fast, Nick M M Wagemaker, Leon E W Janssen, John P Newnham, Matt S Payne, Owen B Spiller, Suhas G Kallapur, Alan H Jobe, Tammo Delhaas, Boris W Kramer, Tim G A M Wolfs
Publikováno v:
PLoS ONE, Vol 12, Iss 6, p e0180114 (2017)
Chorioamnionitis can induce pulmonary inflammation and promote bronchopulmonary dysplasia development, distinguished by alveolar simplification and impaired vascular growth. Chorioamnionitis is more common during the extremely preterm canalicular lun
Externí odkaz:
https://doaj.org/article/a418a035e1d843ffbd4733494521eab7
Autor:
Mavis Puopelle Dakorah, Elizabeth Agyare, Joseph Elikem Efui Acolatse, George Akafity, John Stelling, Victoria J. Chalker, Owen B. Spiller, Nana Benyin Aidoo, Frederick Kumi-Ansah, Daniel Azumah, Stephen Laryea, Robert Incoom, Eric Kofi Ngyedu
Publikováno v:
Antimicrobial Resistance and Infection Control, Vol 11, Iss 1, Pp 1-14 (2022)
Abstract Background Antimicrobial resistance (AMR) is a major public health challenge with its impact felt disproportionately in Western Sub-Saharan Africa. Routine microbiology investigations serve as a rich source of AMR monitoring and surveillance
Externí odkaz:
https://doaj.org/article/6337d786b7da45e19cf123f7e89197a9
Autor:
Kirsty Sands, Maria J. Carvalho, Owen B. Spiller, Edward A. R. Portal, Kathryn Thomson, William John Watkins, Jordan Mathias, Calie Dyer, Chinenye Akpulu, Robert Andrews, Ana Ferreira, Thomas Hender, Rebecca Milton, Maria Nieto, Rabaab Zahra, Haider Shirazi, Adil Muhammad, Shermeen Akif, Muhammad Hilal Jan, Kenneth Iregbu, Fatima Modibbo, Stella Uwaezuoke, Grace J. Chan, Delayehu Bekele, Semaria Solomon, Sulagna Basu, Ranjan Kumar Nandy, Sharmi Naha, Jean-Baptiste Mazarati, Aniceth Rucogoza, Lucie Gaju, Shaheen Mehtar, Andre N. H. Bulabula, Andrew Whitelaw, BARNARDS Group, Timothy R. Walsh
Publikováno v:
BMC Infectious Diseases, Vol 22, Iss 1, Pp 1-16 (2022)
Abstract Background In low- and middle-income countries (LMIC) Staphylococcus aureus is regarded as one of the leading bacterial causes of neonatal sepsis, however there is limited knowledge on the species diversity and antimicrobial resistance cause
Externí odkaz:
https://doaj.org/article/b99a40e2deec4c4c8a38edd2aca6709a
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
Long-read sequencing (LRS) can resolve repetitive regions, a limitation of short read (SR) data. Reduced cost and instrument size has led to a steady increase in LRS across diagnostics and research. Here, we re-basecalled FAST5 data sequenced between
Externí odkaz:
https://doaj.org/article/7b76605b8114415488f1438d4753bc8a
Autor:
Ioannis Pavlidis, Owen B. Spiller, Gabriella Sammut Demarco, Heather MacPherson, Sarah E. M. Howie, Jane E. Norman, Sarah J. Stock
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Ureaplasma parvum is often isolated from intrauterine infections, which are associated with 40% of preterm births. Here, Pavlidis et al. present a mouse model of ascending U. parvum infection that resembles human disease, and show that mild cervical
Externí odkaz:
https://doaj.org/article/d709abe271f6429286256336780462eb
Autor:
Daan R. M. G. Ophelders, Agnes W. Boots, Matthias C. Hütten, Salwan Al-Nasiry, Reint K. Jellema, Owen B. Spiller, Frederik-Jan van Schooten, Agnieszka Smolinska, Tim G. A. M. Wolfs
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Chorioamnionitis is a major risk factor for preterm birth and an independent risk factor for postnatal morbidity for which currently successful therapies are lacking. Emerging evidence indicates that the timing and duration of intra-amniotic infectio
Externí odkaz:
https://doaj.org/article/ca67e004cb8e4a74ae8b860223421b3a
Autor:
Qiue Yang, Mei Li, Owen B. Spiller, Diego O. Andrey, Philip Hinchliffe, Hui Li, Craig MacLean, Pannika Niumsup, Lydia Powell, Manon Pritchard, Andrei Papkou, Yingbo Shen, Edward Portal, Kirsty Sands, James Spencer, Uttapoln Tansawai, David Thomas, Shaolin Wang, Yang Wang, Jianzhong Shen, Timothy Walsh
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-12 (2017)
The plasmid-encoded MCR-1 enzyme modifies bacterial lipid A, thus conferring resistance to the antibiotic colistin. Here, Yang et al. show that MCR-1 expression can decrease in vitro growth rate, fitness and immune stimulation, and can reduce virulen
Externí odkaz:
https://doaj.org/article/a6d761a9e3b7476da168dbb04950f58a
Autor:
Oliver Spiller-Boulter, Susanne Paukner, Ian Boostrom, Kirsty Sands, Edward A. R. Portal, Owen B. Spiller
Publikováno v:
Antibiotics, Vol 10, Iss 11, p 1370 (2021)
Lefamulin is the first of the pleuromutilin class of antimicrobials to be available for therapeutic use in humans. Minimum inhibitory concentrations of lefamulin were determined by microbroth dilution for 90 characterised clinical isolates (25 Ureapl
Externí odkaz:
https://doaj.org/article/bc719c3f63ca4dcc8b8fbc8c3bbac62d
Autor:
Martin Sharratt, Kirsty Sands, Edward A. R. Portal, Ian Boostrom, Brian A. Mondeja, Nadia M. Rodríguez, Lucy C. Jones, Owen B. Spiller
Publikováno v:
Antibiotics, Vol 10, Iss 11, p 1379 (2021)
Often dismissed as a commensal, Mycoplasma hominis is an increasingly prominent target of research due to its role in septic arthritis and organ transplant failure in immunosuppressed patients, particularly lung transplantation. As a mollicute, its h
Externí odkaz:
https://doaj.org/article/2edb7604716b44d0a02ed95ba16e6f08