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pro vyhledávání: '"Owen Adam Brady"'
Autor:
Xiaolai Zhou, Lirong Sun, Oliver Bracko, Ji Whae Choi, Yan Jia, Alissa L. Nana, Owen Adam Brady, Jean C. Cruz Hernandez, Nozomi Nishimura, William W. Seeley, Fenghua Hu
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-14 (2017)
Mutations in the granulin gene are associated with frontotemporal lobe dementia (FTLD) and a lysosomal storage disease. The authors show that reduced progranulin levels leads to impaired neuronal uptake and lysosomal delivery of prosaposin, and that
Externí odkaz:
https://doaj.org/article/41d78f62c0c2475397bd2fa199e6bc5b
