High-Specificity CRISPR-Mediated Genome Engineering in Anti-BCMA Allogeneic CAR T Cells Suppresses Allograft Rejection in Preclinical Models.

Autor: Degagné É; Caribou Biosciences, Inc., Berkeley, California., Donohoue PD; Caribou Biosciences, Inc., Berkeley, California., Roy S; Caribou Biosciences, Inc., Berkeley, California., Scherer J; Caribou Biosciences, Inc., Berkeley, California., Fowler TW; Caribou Biosciences, Inc., Berkeley, California., Davis RT; Caribou Biosciences, Inc., Berkeley, California., Reyes GA; Caribou Biosciences, Inc., Berkeley, California., Kwong G; Caribou Biosciences, Inc., Berkeley, California., Stanaway M; Caribou Biosciences, Inc., Berkeley, California., Larroca Vicena V; Caribou Biosciences, Inc., Berkeley, California., Mutha D; Caribou Biosciences, Inc., Berkeley, California., Guo R; Caribou Biosciences, Inc., Berkeley, California., Edwards L; Caribou Biosciences, Inc., Berkeley, California., Schilling B; Caribou Biosciences, Inc., Berkeley, California., Shaw M; Caribou Biosciences, Inc., Berkeley, California., Smith SC; Caribou Biosciences, Inc., Berkeley, California., Kohrs B; Caribou Biosciences, Inc., Berkeley, California., Kufeldt HJ; Caribou Biosciences, Inc., Berkeley, California., Churchward G; Caribou Biosciences, Inc., Berkeley, California., Ruan F; Caribou Biosciences, Inc., Berkeley, California., Nyer DB; Caribou Biosciences, Inc., Berkeley, California., McSweeney K; Caribou Biosciences, Inc., Berkeley, California., Irby MJ; Caribou Biosciences, Inc., Berkeley, California., Fuller CK; Caribou Biosciences, Inc., Berkeley, California., Banh L; Caribou Biosciences, Inc., Berkeley, California., Toh MS; Caribou Biosciences, Inc., Berkeley, California., Thompson M; Caribou Biosciences, Inc., Berkeley, California., Owen ALG; Caribou Biosciences, Inc., Berkeley, California., An Z; Caribou Biosciences, Inc., Berkeley, California., Gradia S; Caribou Biosciences, Inc., Berkeley, California., Skoble J; Caribou Biosciences, Inc., Berkeley, California., Bryan M; Caribou Biosciences, Inc., Berkeley, California., Garner E; Caribou Biosciences, Inc., Berkeley, California., Kanner SB; Caribou Biosciences, Inc., Berkeley, California.

Publikováno v: Cancer immunology research [Cancer Immunol Res] 2024 Apr 02; Vol. 12 (4), pp. 462-477.

Harnessing type I CRISPR-Cas systems for genome engineering in human cells.

Autor: Cameron P; Caribou Biosciences, Inc., Berkeley, CA, USA. pscameron@cariboubio.com., Coons MM; Caribou Biosciences, Inc., Berkeley, CA, USA., Klompe SE; Caribou Biosciences, Inc., Berkeley, CA, USA.; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA., Lied AM; Caribou Biosciences, Inc., Berkeley, CA, USA., Smith SC; Caribou Biosciences, Inc., Berkeley, CA, USA., Vidal B; Caribou Biosciences, Inc., Berkeley, CA, USA., Donohoue PD; Caribou Biosciences, Inc., Berkeley, CA, USA., Rotstein T; Caribou Biosciences, Inc., Berkeley, CA, USA.; Biomedical Engineering, Duke University, Durham, NC, USA., Kohrs BW; Caribou Biosciences, Inc., Berkeley, CA, USA., Nyer DB; Caribou Biosciences, Inc., Berkeley, CA, USA., Kennedy R; Caribou Biosciences, Inc., Berkeley, CA, USA.; Invitae Corporation, San Francisco, CA, USA., Banh LM; Caribou Biosciences, Inc., Berkeley, CA, USA., Williams C; Caribou Biosciences, Inc., Berkeley, CA, USA., Toh MS; Caribou Biosciences, Inc., Berkeley, CA, USA., Irby MJ; Caribou Biosciences, Inc., Berkeley, CA, USA., Edwards LS; Caribou Biosciences, Inc., Berkeley, CA, USA., Lin CH; Caribou Biosciences, Inc., Berkeley, CA, USA., Owen ALG; Caribou Biosciences, Inc., Berkeley, CA, USA., Künne T; Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands., van der Oost J; Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands., Brouns SJJ; Laboratory of Microbiology, Department of Agrotechnology and Food Sciences, Wageningen University, Wageningen, The Netherlands.; Kavli Institute of Nanoscience, Department of Bionanoscience, Delft University of Technology, Delft, The Netherlands., Slorach EM; Caribou Biosciences, Inc., Berkeley, CA, USA., Fuller CK; Caribou Biosciences, Inc., Berkeley, CA, USA., Gradia S; Caribou Biosciences, Inc., Berkeley, CA, USA., Kanner SB; Caribou Biosciences, Inc., Berkeley, CA, USA., May AP; Caribou Biosciences, Inc., Berkeley, CA, USA.; Sana Biotechnology, South San Francisco, CA, USA., Sternberg SH; Caribou Biosciences, Inc., Berkeley, CA, USA. shsternberg@gmail.com.; Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY, USA. shsternberg@gmail.com.

Publikováno v: Nature biotechnology [Nat Biotechnol] 2019 Dec; Vol. 37 (12), pp. 1471-1477. Date of Electronic Publication: 2019 Nov 18.