Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Owais B. Chaudhri"'
Autor:
John W, Delahunt, Hayley J, Denison, Jane, Kennedy, Jackie, Hilton, Heather, Young, Owais B, Chaudhri, Marianne S, Elston
Publikováno v:
The New Zealand medical journal. 129(1434)
In light of the rising number of referrals to secondary level services of people who identify as transgender, and the Human Rights Commission concerns regarding the care of this group in New Zealand, we felt it was timely to determine the availabilit
Autor:
Alexis Fowler, Waljit S. Dhillo, Sagen Zac-Varghese, Radha Ramachandran, Sailesh Kumar, Catherine Williamson, Krishna Chinthapalli, Emily L. Thompson, Michael Patterson, Mohammad A. Ghatei, Stephen R. Bloom, Kevin Murphy, Gurjinder Nijher, Owais B. Chaudhri
Publikováno v:
British Journal of Clinical Pharmacology. 70:674-681
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT • Kisspeptin potently stimulates gonadotrophin release in humans and therefore represents a potential therapy for disorders of reproduction. However, ex vivo studies on human tissue suggest that kisspeptin h
Autor:
Stephen R. Bloom, Iain Pritchard, James R.C. Parkinson, Waljit S. Dhillo, Caroline J. Small, Owais B. Chaudhri, M. A. Ghatei, Stanley Moore, Gavin A. Bewick
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 294:E698-E708
Peptide YY (PYY) is secreted postprandially from the endocrine L cells of the gastrointestinal tract. PYY3-36, the major circulating form of the peptide, is thought to reduce food intake in humans and rodents via high-affinity binding to the autoinhi
Publikováno v:
Annual Review of Physiology. 70:239-255
The increasing prevalence of obesity worldwide has imparted renewed impetus to the study of the mechanisms of appetite regulation. Digestion and nutrient absorption take place in the gastrointestinal (GI) tract, whereas food intake is controlled by n
Autor:
Maralyn Druce, Sarah Stanley, Mohammad A. Ghatei, Stephen R. Bloom, Yu-Ting Kuo, Owais B. Chaudhri, James R.C. Parkinson, Waljit S. Dhillo, Amy H. Herlihy, Jimmy D. Bell
Publikováno v:
Biochemical and Biophysical Research Communications. 350:298-306
The anorexigenic gut hormones oxyntomodulin (OXM) and glucagon-like peptide-1 (GLP-1) are thought to physiologically regulate appetite and food intake. Using manganese-enhanced magnetic resonance imaging, we have shown distinct patterns of neuronal a
Publikováno v:
Drug Discovery Today: Disease Mechanisms. 2:289-294
The increasing incidence of obesity worldwide has renewed interest in the control of food intake and energy homeostasis. The brain–gut axis is central to the mechanism by which the periphery signals energy status to central nervous appetite centres
Autor:
Gurjinder M K, Nijher, Owais B, Chaudhri, Radha, Ramachandran, Kevin G, Murphy, Sagen E K, Zac-Varghese, Alexis, Fowler, Krishna, Chinthapalli, Michael, Patterson, Emily L, Thompson, Catherine, Williamson, Sailesh, Kumar, Mohammad A, Ghatei, Stephen R, Bloom, Waljit S, Dhillo
Publikováno v:
British journal of clinical pharmacology. 70(5)
To investigate (i) if kisspeptin administration alters heart rate (HR) or blood pressure (BP) in healthy male and female volunteers, (ii) whether circulating plasma kisspeptin concentrations in healthy pregnant women and women with hypertensive disea
Publikováno v:
Nature reviews. Endocrinology. 6(8)
Food intake and energy expenditure are tightly regulated by the brain, in a homeostatic process that integrates diverse hormonal, neuronal and metabolic signals. The gastrointestinal tract is an important source of such signals, which include several
Autor:
Stephen R. Bloom, Gurjinder Nijher, Kevin Murphy, Owais B. Chaudhri, Gavin A. Bewick, Radha Ramachandran, Anna-Mary Young, Jonathan Waxman, Waljit S. Dhillo, M. A. Ghatei, Annette E. Curtis
Publikováno v:
Oncology Reports. 23
Kisspeptin, the product of the KiSS-1 gene, inhibits metastasis and stimulates the hypothalamo-pituitary-gonadal axis. Kisspeptin is therefore a putative target in the treatment of hormone-sensitive malignancies. Prostatic carcinoma remains a signifi
Autor:
Gurjinder M. K. Nijher, Catherine Williamson, Alexis Fowler, Owais B. Chaudhri, Jordan E. Baxter, Krishna Chinthapalli, Kevin Murphy, Waljit S. Dhillo, Sailesh Kumar, Channa N. Jayasena, Radha Ramachandran, Mohammad A. Ghatei, Stephen R. Bloom, Michael Patterson
Publikováno v:
Clinical chemistry. 56(6)
Kisspeptin is the product of the KISS1 1 (KiSS-1 metastasis-suppressor) gene and is the ligand for the G-protein–coupled receptor, now known as the KISS1 receptor (KISS1R)2 (1). Both kisspeptin and KISS1R play a crucial role in the regulation of re