Pharmacokinetics and pharmacodynamics of once-weekly administration of JR-142, a long-acting albumin-fused human growth hormone: A rondemized, placebo-controlled phase 1 study

Autor: Owada, Yasuko, Okazaki, Mika, Ikeda, Toshiaki, Yamamoto, Ryuji, Minami, Kohtaro, Takahashi, Kenichi, Hirato, Tohru, Mita, Yoko, Yamamoto, Tatsuyoshi, Tanizawa, Kazunori, Sonoda, Hiroyuki, Sato, Yuji

Publikováno v: In Growth Hormone & IGF Research December 2022 67

Newly formulated GROWJECT® is bioequivalent to the prior GROWJECT® formulation and causes less injection-associated pain

Autor: Owada, Yasuko, Asano, Yuuka, Hanada, Takashi, Yasukawa, Hidehito, Yamaoka, Mariko, Mita, Yoko, Namba, Noriyuki

Publikováno v: Clinical Pediatric Endocrinology

Daily treatment with subcutaneous injections of recombinant human GH can be physically and emotionally stressful for children and their caregivers owing to the pain caused by injection. In this study, 52 healthy male subjects were randomized to inves

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3a962f73208ec08fd410c934093e8670
http://europepmc.org/articles/PMC7783130

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Newly formulated GROWJECT ^® is bioequivalent to the prior GROWJECT ^® formulation and causes less injection-associated pain.

Autor: Owada Y; Medical Corporation Heishinkai OPHAC Hospital, Osaka, Japan., Asano Y; Research Division, CMC Development Research, Analytical & Formulation Research Unit, Formulation Development, JCR Pharmaceuticals Co., Ltd., Hyogo, Japan., Hanada T; Research Division, CMC Development Research, Analytical & Formulation Research Unit, Formulation Development, JCR Pharmaceuticals Co., Ltd., Hyogo, Japan., Yasukawa H; Research Division, CMC Development Research, Analytical & Formulation Research Unit, Formulation Development, JCR Pharmaceuticals Co., Ltd., Hyogo, Japan., Yamaoka M; Development Division, JCR Pharmaceuticals Co., Ltd., Hyogo, Japan., Mita Y; Development Division, JCR Pharmaceuticals Co., Ltd., Hyogo, Japan., Namba N; Division of Pediatrics and Perinatology, Faculty of Medicine, Tottori University, Tottori, Japan.

Publikováno v: Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology [Clin Pediatr Endocrinol] 2021; Vol. 30 (1), pp. 35-40. Date of Electronic Publication: 2021 Jan 05.