Anti-Cytokine Therapy to Attenuate Ischemic-Reperfusion Associated Brain Injury in the Perinatal Period

Autor: Clémence Disdier, Xiaodi Chen, Jeong-Eun Kim, Steven W. Threlkeld, Barbara S. Stonestreet

Publikováno v: Brain Sciences, Vol 8, Iss 6, p 101 (2018)

Perinatal brain injury is a major cause of morbidity and long-standing disability in newborns. Hypothermia is the only therapy approved to attenuate brain injury in the newborn. However, this treatment is unfortunately only partially neuroprotective

Externí odkaz: https://doaj.org/article/246aa4d8ad784fb8995656c9b152cab0

Hypothyroidism in utero suppresses pituitary-adrenal function in the ovine fetus near term: Implications for fetal maturation and the timing of birth

Autor: Abigail L. Fowden, Isabella Inzani, India R. Lloyd, Katie L. Davies, Emily J. Camm, Alison J. Forhead, Blasio Miles J De, Wooding F. B. Peter

Publikováno v: Endocrine Abstracts.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1e9ffe2f0f969bc043c05cff7d6ead4e
https://doi.org/10.1530/endoabs.70.aep1104

Changes in Cellular Localization of Inter-Alpha Inhibitor Proteins after Cerebral Ischemia in the Near-Term Ovine Fetus

Autor: Boram Kim, Alistair J. Gunn, Joanne O. Davidson, Yow-Pin Lim, Barbara S. Stonestreet, Laura Bennet, Kazuki Hatayama, Xiaodi Chen

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10751, p 10751 (2021)

Inter-alpha Inhibitor Proteins (IAIPs) are key immunomodulatory molecules. Endogenous IAIPs are present in human, rodent, and sheep brains, and are variably localized to the cytoplasm and nuclei at multiple developmental stages. We have previously re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc97b237bcfc0cb67458e3637688c3e6
https://doi.org/10.3390/ijms221910751

Anti-Cytokine Therapy to Attenuate Ischemic-Reperfusion Associated Brain Injury in the Perinatal Period

Autor: Jeong Eun Kim, Barbara S. Stonestreet, Clémence Disdier, Steven W. Threlkeld, Xiaodi Chen

Publikováno v: Brain Sciences, Vol 8, Iss 6, p 101 (2018)
Brain Sciences

Perinatal brain injury is a major cause of morbidity and long-standing disability in newborns. Hypothermia is the only therapy approved to attenuate brain injury in the newborn. However, this treatment is unfortunately only partially neuroprotective

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0ef5e89b08fe5ab48588866047e2127
http://www.mdpi.com/2076-3425/8/6/101

Sustained hypoxemia in late gestation potentiates hepatic gluconeogenic gene expression but does not activate glucose production in the ovine fetus

Autor: Laura D. Brown, Stephanie R. Wesolowski, William W. Hay, Sean W. Limesand, A. K. Jones, Paul J. Rozance, David A. Goldstrohm

Publikováno v: Am J Physiol Endocrinol Metab

Fetal hypoxemia is associated with pregnancy conditions that cause an early activation of fetal glucose production. However, the independent role of hypoxemia to activate this pathway is not well understood. We hypothesized that fetal hypoxemia would

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1712b20e727cdb93101ee8b2b6e1cddb
https://pubmed.ncbi.nlm.nih.gov/30964701