Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Overed-Sayer Catherine L"'
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Autor:
Asghar, Sabha, Monkley, Susan, Smith, David J. F., Hewitt, Richard J., Grime, Ken, Murray, Lynne A., Overed-Sayer, Catherine L., Molyneaux, Philip L.
Additional file 1: Figure S1. DHBEs have a greater expression of senescent markers, compared to NHBEs (A-D) Increased SASP release including IL6, IL8, PAI1 and TNF-a. (E-J) Increased senescence related gene expression including p16, p21, p27, p15, Si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::835171c3f8ad0822e6855071d216e78e
Autor:
Stephenson, Katherine E., Porte, Joanne, Kelly, Aoife, Wallace, William A., Huntington, Catherine E., Overed-Sayer, Catherine L., Cohen, E. Suzanne, Jenkins, R. Gisli, John, Alison E.
Additional file 1. Figure S1. Whole IL-33 western blot for Fig. 1F. Basal IL-33 protein expression by non-IPF (n=3) and IPF (n=4) HLFs assessed by western blot. 20 µg protein/lane loaded for HLF and HUVEC (HUV.) lysates. α-Tubulin was used as a loa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::026e9d325eafe9bea56626fb2bd0f529
Autor:
Graham Belfield, Doris Rassl, Damian C. Crowther, Richard Berks, Ewa Kolosionek, Helen Parfrey, Marisa Coetzee, Nicola Davis, Maryam Clausen, Susan J. Monkley, Overed-Sayer Catherine L, Cory M. Hogaboam, Leire Escudero-Ibarz, Lynne Murray, Leia R. Griffin, Maria Karlsson, Alan Carruthers
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-15 (2021)
The unfolded protein response (UPR) is a direct consequence of cellular endoplasmic reticulum (ER) stress and a key disease driving mechanism in IPF. The resolution of the UPR is directed by PPP1R15A (GADD34) and leads to the restoration of normal ri
Autor:
Susan J. Monkley, Overed-Sayer Catherine L, V Ptasinski, Lynne Murray, P Hazon, K Öst, M Tammia, Darcy E. Wagner
Publikováno v:
Mechanisms of lung injury and repair.
Autor:
V Ptasinski, Susan J. Monkley, Overed-Sayer Catherine L, Lynne Murray, K Öst, Darcy E. Wagner, P Hazon, M Tammia
Publikováno v:
03.03 - Mechanisms of lung injury and repair.
Introduction: Dysregulation of the alveolar epithelium by repeated injury is recognised as a driver of idiopathic pulmonary fibrosis (IPF). However, access to relevant pre-clinical models of alveolar epithelial injury in IPF is limited. Aims and obje
Autor:
Overed-Sayer Catherine L, Matthew A. Sleeman, Ana Camelo, Yoichiro Ohne, Guglielmo Rosignoli, Ross Stewart, Richard D. May
Publikováno v:
Blood Advances. 1:577-589
Innate lymphoid cells (ILCs) represent a distinct branch of the lymphoid lineage composed of 3 major subpopulations: ILC1, ILC2, and ILC3. ILCs are mainly described as tissue-resident cells but can be detected at low levels in human blood. However, u
Autor:
Gülin Güler-Gane, Arthur Lewis, Rebecca Dunmore, Deborah Clarke, Lorea Beloki, Overed-Sayer Catherine L, Helen Parfrey, Amina Chahboub, Richard D. May, Doris Rassl, Sofia Koch, M. Kuziora, Elena Miranda, Alan Carruthers, Lynne Murray, Elena Liarte Marin
Publikováno v:
Thorax
BackgroundIdiopathic pulmonary fibrosis (IPF) is a chronic and progressive lung disease which presents a grave prognosis for diagnosed patients. Nintedanib (a triple tyrosine kinase inhibitor) and pirfenidone (unclear mechanism of action) are the onl
Publikováno v:
Cellular insights into lung injury repair.
Introduction Idiopathic pulmonary fibrosis (IPF) is a debilitating interstitial lung disease with a poor prognosis and limited treatment options. It is a chronic, progressive, condition characterised by the excessive deposition of extracellular matri