Výsledky vyhledávání - "Ovarian Neoplasms/metabolism"

Hormone receptor expression patterns define clinically meaningful subgroups of endometrioid ovarian carcinoma

Autor: Michael Churchman, Tzyvia Rye, Fiona Nussey, Melanie Mackean, Robert L Hollis, Charlie Gourley, Yasushi Iida, John P. Thomson, C. Simon Herrington, Barbara Stanley

Publikováno v: Gynecologic Oncology
Hollis, R, Stanley, B, Iida, Y, Thomson, J, Churchman, M, Rye, T, Mackean, M J, Nussey, F, Gourley, C & Herrington, C S 2019, ' Hormone receptor expression patterns define clinically meaningful subgroups of endometrioid ovarian carcinoma ', Gynecologic Oncology, vol. 155, no. 2, pp. 318-323 . https://doi.org/10.1016/j.ygyno.2019.09.001, https://doi.org/10.1016/j.ygyno.2019.09.001

Background Numerous studies have investigated the association between hormone receptor expression and clinical outcome in ovarian carcinoma (OC); however, these have largely focussed on serous OCs, with few studies reporting specifically on endometri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::200b8cdaa79e130432ff75817701585f
http://europepmc.org/articles/PMC6854467

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Stiffness increases with myofibroblast content and collagen density in mesenchymal high grade serous ovarian cancer

Autor: Foucauld Chamming's, Thomas Guilbert, Virginie Mieulet, Elisabetta Marangoni, Anne Vincent-Salomon, Fatima Mechta-Grigoriou, Yann Kieffer, Fariba Nemati, Camille Garnier, Gilles Renault

Publikováno v: Scientific Reports
Scientific Reports, 2021, 11 (1), pp.4219. ⟨10.1038/s41598-021-83685-0⟩
Scientific Reports, Vol 11, Iss 1, Pp 1-20 (2021)

Women diagnosed with high-grade serous ovarian cancers (HGSOC) are still likely to exhibit a bad prognosis, particularly when suffering from HGSOC of the Mesenchymal molecular subtype (50% cases). These tumors show a desmoplastic reaction with accumu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ebc6698c39c3864f71f7f005ae0bdd1
https://ut3-toulouseinp.hal.science/hal-03778944

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Measuring trogocytosis between ovarian tumor and natural killer cells

Autor: Antonio Delgado-Gonzalez, Ying-Wen Huang, Ermelinda Porpiglia, Kenyi Donoso, Veronica D. Gonzalez, Wendy J. Fantl

Publikováno v: Delgado-Gonzalez, A, Huang, Y-W, Porpiglia, E, Donoso, K, Gonzalez, V D & Fantl, W J 2022, ' Measuring trogocytosis between ovarian tumor and natural killer cells ', STAR Protocols, vol. 3, no. 2, 101425 . https://doi.org/10.1016/j.xpro.2022.101425

Trogocytosis is an active transport mechanism by which one cell extracts a plasma membrane fragment with embedded molecules from an adjacent cell in a contact-dependent process leading to the acquisition of a new function. Our protocol, which has gen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00d0ba4b59cabeac420d144638cfa94b
https://doi.org/10.1016/j.xpro.2022.101425

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MyD88 and TLR4 Expression in Epithelial Ovarian Cancer

Autor: Matthew S. Block, Robert A. Vierkant, Peter F. Rambau, Stacey J. Winham, Philipp Wagner, Nadia Traficante, Aleksandra Tołoczko, Daniel G. Tiezzi, Florin Andrei Taran, Peter Sinn, Weiva Sieh, Raghwa Sharma, Joseph H. Rothstein, Teresa Ramón y Cajal, Luis Paz-Ares, Oleg Oszurek, Sandra Orsulic, Roberta B. Ness, Gregg Nelson, Francesmary Modugno, Janusz Menkiszak, Valerie McGuire, Bryan M. McCauley, Marie Mack, Jan Lubiński, Teri A. Longacre, Zheng Li, Jenny Lester, Catherine J. Kennedy, Kimberly R. Kalli, Audrey Y. Jung, Sharon E. Johnatty, Mercedes Jimenez-Linan, Allan Jensen, Maria P. Intermaggio, Jillian Hung, Esther Herpel, Brenda Y. Hernandez, Andreas D. Hartkopf, Paul R. Harnett, Prafull Ghatage, José M. García-Bueno, Bo Gao, Sian Fereday, Ursula Eilber, Robert P. Edwards, Christiani B. de Sousa, Jurandyr M. de Andrade, Anita Chudecka-Głaz, Georgia Chenevix-Trench, Alicia Cazorla, Sara Y. Brucker, Jennifer Alsop, Alice S. Whittemore, Helen Steed, Annette Staebler, Kirsten B. Moysich, Usha Menon, Jennifer M. Koziak, Stefan Kommoss, Susanne K. Kjaer, Linda E. Kelemen, Beth Y. Karlan, David G. Huntsman, Estrid Høgdall, Jacek Gronwald, Marc T. Goodman, Blake Gilks, María José García, Peter A. Fasching, Anna de Fazio, Suha Deen, Jenny Chang-Claude, Francisco J. Candido dos Reis, Ian G. Campbell, James D. Brenton, David D. Bowtell, Javier Benítez, Paul D.P. Pharoah, Martin Köbel, Susan J. Ramus, Ellen L. Goode, D. Bowtell, G. Chenevix-Trench, A. Green, P. Webb, A. DeFazio, D. Gertig, N. Traficante, S. Fereday, S. Moore, J. Hung, K. Harrap, T. Sadkowsky, N. Pandeya, M. Malt, A. Mellon, R. Robertson, T. Vanden Bergh, M. Jones, P. Mackenzie, J. Maidens, K. Nattress, Y.E. Chiew, A. Stenlake, H. Sullivan, B. Alexander, P. Ashover, S. Brown, T. Corrish, L. Green, L. Jackman, K. Ferguson, K. Martin, A. Martyn, B. Ranieri, J. White, V. Jayde, P. Mamers, L. Bowes, L. Galletta, D. Giles, J. Hendley, K. Alsop, T. Schmidt, H. Shirley, C. Ball, C. Young, S. Viduka, Hoa Tran, Sanela Bilic, Lydia Glavinas, Julia Brooks, R. Stuart-Harris, F. Kirsten, J. Rutovitz, P. Clingan, A. Glasgow, A. Proietto, S. Braye, G. Otton, J. Shannon, T. Bonaventura, J. Stewart, S. Begbie, M. Friedlander, D. Bell, S. Baron-Hay, A. Ferrier, G. Gard, D. Nevell, N. Pavlakis, S. Valmadre, B. Young, C. Camaris, R. Crouch, L. Edwards, N. Hacker, D. Marsden, G. Robertson, P. Beale, J. Beith, J. Carter, C. Dalrymple, R. Houghton, P. Russell, M. Links, J. Grygiel, J. Hill, A. Brand, K. Byth, R. Jaworski, P. Harnett, R. Sharma, G. Wain, B. Ward, D. Papadimos, A. Crandon, M. Cummings, K. Horwood, A. Obermair, L. Perrin, D. Wyld, J. Nicklin, M. Davy, M.K. Oehler, C. Hall, T. Dodd, T. Healy, K. Pittman, D. Henderson, J. Miller, J. Pierdes, P. Blomfield, D. Challis, R. McIntosh, A. Parker, B. Brown, R. Rome, D. Allen, P. Grant, S. Hyde, R. Laurie, M. Robbie, D. Healy, T. Jobling, T. Manolitsas, J. McNealage, P. Rogers, B. Susil, E. Sumithran, I. Simpson, K. Phillips, D. Rischin, S. Fox, D. Johnson, S. Lade, M. Loughrey, N. O'Callaghan, W. Murray, P. Waring, V. Billson, J. Pyman, D. Neesham, M. Quinn, C. Underhill, R. Bell, L.F. Ng, R. Blum, V. Ganju, I. Hammond, Y. Leung, A. McCartney, M. Buck, I. Haviv, D. Purdie, D. Whiteman, N. Zeps

Publikováno v: Mayo Clinic proceedings
Australian Ovarian Cancer Study Group 2018, ' MyD88 and TLR4 Expression in Epithelial Ovarian Cancer ', Mayo Clinic Proceedings, vol. 93, no. 3, pp. 307-320 . https://doi.org/10.1016/j.mayocp.2017.10.023
Repositório Institucional da USP (Biblioteca Digital da Produção Intelectual)
Universidade de São Paulo (USP)
instacron:USP
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
MAYO CLINIC PROCEEDINGS
r-IIB SANT PAU. Repositorio Institucional de Producción Científica del Instituto de Investigación Biomédica Sant Pau
Universitat Pompeu Fabra

Objective: To evaluate myeloid differentiation primary response gene 88 (MyD88) and Toll-like receptor 4 (TLR4) expression in relation to clinical features of epithelial ovarian cancer, histologic subtypes, and overall survival. Patients and Methods:

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adf2cae9b0a412f725c26b0ec26021a7
https://doi.org/10.1016/j.mayocp.2017.10.023

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Association of CD31 and p53 With Survival of Ovarian Cancer Patients

Autor: Allan Jensen, Jan Blaakær, Lene Rask, Estrid Høgdall, Lise Christensen, Susanne K. Kjaer, Ib Jarle Christensen, Claus Høgdall

Publikováno v: Rask, L, Høgdall, C K, Kjaer, S K, Christensen, L, Jensen, A, Blaakaer, J, Christensen, I J & Høgdall, E V S 2019, ' Association of CD31 and p53 with survival of ovarian cancer patients ', Anticancer Research, vol. 39, no. 2, pp. 567-576 . https://doi.org/10.21873/anticanres.13149

Background/Aim: New markers for ovarian cancer are needed. This study aimed to examine the expression of tumour cell p53 and endothelial cell CD31 proteins and correlate them to clinicopathological factors. Patients and Methods: Expression of protein

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4d7c04f9a6908875e59fc9781895178
https://pubmed.ncbi.nlm.nih.gov/30711931

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Shieldin complex promotes DNA end-joining and counters homologous recombination in BRCA1-null cells

Publikováno v: Nature Cell Biology
Nature Cell Biology, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩
Nature cell biology
Nature Cell Biology, Nature Publishing Group, 2018, 20 (8), pp.954-965. ⟨10.1038/s41556-018-0140-1⟩

International audience; BRCA1 deficiencies cause breast, ovarian, prostate and other cancers, and render tumours hypersensitive to poly(ADP-ribose) polymerase (PARP) inhibitors. To understand the resistance mechanisms, we conducted whole-genome CRISP

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94c03882fb1aad0056e71d15c34e8ed4
https://www.repository.cam.ac.uk/handle/1810/282947

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Sensitive and frequent identification of high avidity neo-epitope specific CD8 + T cells in immunotherapy-naive ovarian cancer

Publikováno v: Nature communications, vol. 9, no. 1, pp. 1092
Nature Communications, Vol 9, Iss 1, Pp 1-10 (2018)

Immunotherapy directed against private tumor neo-antigens derived from non-synonymous somatic mutations is a promising strategy of personalized cancer immunotherapy. However, feasibility in low mutational load tumor types remains unknown. Comprehensi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1919f934ded5e32fd9ef810386741640
https://serval.unil.ch/notice/serval:BIB_10AE95ADCEE8

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Identification of germ cells at risk for neoplastic transformation in gonadoblastoma

Publikováno v: Human pathology. 36(5):512-21

Carcinoma in situ (CIS) is the precursor of malignant testicular germ cell tumors (GCTs) of adolescents and young adults, being the neoplastic counterpart of primordial germ cells/gonocytes. Carcinoma in situ cells will develop into invasive seminoma

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dris___00893::66148661a4022c6c019aa22e03ec7a98
https://doi.org/10.1016/j.humpath.2005.02.016

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