Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies

Autor: Thomas P. Conrads, Connie R. Jimenez, Xiu-Xuan Sun, Sebastien Gallien, Stuart J. Cordwell, Sandra Goetze, Kelly A. Conrads, Martin R. Larsen, Andrew Macklin, Yue Xuan, Benjamin L. Parker, Yu-Ju Chen, Sander R. Piersma, Davide Chiasserini, Amanda Khoo, Bernd Wollscheid, Nicholas W. Bateman, Ben Crossett, Hongwen Zhu, Siqi Liu, Mo Hu, Zhi-Nan Chen, Pedro Navarro, Muhammad Tahir, Reta Birhanu Kitata, Albert Sickmann, Yue Zhou, Hu Zhou, Brian L. Hood, Christina Loosse, Guixue Hou, Niyati Parikh, Thomas Kislinger

Publikováno v: Nature Communications, 11(1):5248. Nature Publishing Group UK
Xuan, Y, Bateman, N W, Gallien, S, Goetze, S, Zhou, Y, Navarro, P, Hu, M, Parikh, N, Hood, B L, Conrads, K A, Loosse, C, Kitata, R B, Piersma, S R, Chiasserini, D, Zhu, H, Hou, G, Tahir, M, Macklin, A, Khoo, A, Sun, X, Crossett, B, Sickmann, A, Chen, Y J, Jimenez, C R, Zhou, H, Liu, S, Larsen, M R, Kislinger, T, Chen, Z, Parker, B L, Cordwell, S J, Wollscheid, B & Conrads, T P 2020, ' Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies ', Nature Communications, vol. 11, 5248 . https://doi.org/10.1038/s41467-020-18904-9
Nature Communications, 11 (1)
Xuan, Y, Bateman, N W, Gallien, S, Goetze, S, Zhou, Y, Navarro, P, Hu, M, Parikh, N, Hood, B L, Conrads, K A, Loosse, C, Kitata, R B, Piersma, S R, Chiasserini, D, Zhu, H, Hou, G, Tahir, M, Macklin, A, Khoo, A, Sun, X, Crossett, B, Sickmann, A, Chen, Y J, Jimenez, C R, Zhou, H, Liu, S, Larsen, M R, Kislinger, T, Chen, Z, Parker, B L, Cordwell, S J, Wollscheid, B & Conrads, T P 2020, ' Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies ', Nature Communications, vol. 11, no. 1, 5248 . https://doi.org/10.1038/s41467-020-18904-9
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Nature Communications

Cancer has no borders: Generation and analysis of molecular data across multiple centers worldwide is necessary to gain statistically significant clinical insights for the benefit of patients. Here we conceived and standardized a proteotype data gene

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e9a590089c5d4fc0871035558e98f3ad
https://research.vumc.nl/en/publications/39244c25-49e3-47cf-ab52-9eb1dfe44975

Clinicopathologic study of vascular endothelial growth factor, thrombospondin-1, and microvessel density assessed by CD34 in patients with stage III ovarian carcinoma

Autor: Karavasilis, V., Malamou-Mitsi, Vassiliki D., Briassoulis, E. Ch, Tsanou, E., Kitsou, E., Pavlidis, Nicholas

Publikováno v: International Journal of Gynecological Cancer

The aim of the study was to investigate angiogenesis in patients with advanced-stage ovarian carcinoma. We used paraffin-embedded tumor tissues from 33 patients diagnosed with FIGO III ovarian cancer who had optimal surgery and received platinum-base

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ca76e441beb193da1df7ad73556c7226
https://doi.org/10.1136/ijgc-00009577-200602001-00039

Drug resistance-associated markers P-glycoprotein, multidrug resistance-associated protein 1, multidrug resistance-associated protein 2, and lung resistance protein as prognostic factors in ovarian carcinoma

Autor: Arts, H. J., Katsaros, D., Elisabeth de Vries, Massobrio, M., Genta, F., Danese, S., Arisio, R., Scheper, R. J., Kool, M., Scheffer, G. L., Willemse, P. H., Ate van der Zee, Albert Suurmeijer

Publikováno v: University of Groningen
Clinical Cancer Research, 5(10), 2798-2805. AMER ASSOC CANCER RESEARCH
Clinical cancer research, 5(10), 2798-2805. American Association for Cancer Research Inc.

Intrinsic and/or acquired resistance to chemotherapy is the major obstacle to overcome in the treatment of patients with ovarian carcinoma. The aim of the present study was to investigate the prognostic value of drug resistance-associated proteins P-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::cced3f932c2cb87a857753378e0e9b63
https://research.rug.nl/en/publications/098956b2-bee4-452b-ba70-d3856c77c6bd