Zobrazeno 1 - 10
of 184
pro vyhledávání: '"Ovarian Clear Cell Adenocarcinoma"'
Publikováno v:
Journal of Ovarian Research, Vol 11, Iss 1, Pp 1-7 (2018)
Abstract Background Alpha-fetoprotein (AFP) is a useful tumor marker for ovarian germ cell tumors, particularly yolk sac tumor (YST). It is valuable for both diagnosis and further follow-up. Epithelial ovarian carcinoma (EOC) rarely secretes AFP, esp
Externí odkaz:
https://doaj.org/article/1749846b819349158e05a1d8609433e7
Autor:
Elizabeth L. Christie, David Shi Hao Liu, David D.L. Bowtell, Chris Mitchell, Walid J Azar, George Au-Yeung
Publikováno v:
Cancer Research. 80:4960-4971
Ovarian clear cell adenocarcinoma (OCCA) is characterized by a particularly poor response to conventional chemotherapy and a short overall survival time in women with established disease. The development of targeted treatments for OCCA relies on a be
Publikováno v:
Molecular and Clinical Oncology
The association between iron ions and endometriosis-associated ovarian cancer (EAOC) has been previously investigated to elucidate EAOC carcinogenesis; however, the dynamics of iron deposition in the endometrial epithelium and endometrial stroma of o
Autor:
Hee Seung Kim, Michael Friedlander, Nivashini Kaliaperumal, John E. Connolly, Geraldine Goss, Jae Weon Kim, Jeffrey C. Goh, DIana G.Z. Lim, Bee Choo Tai, Natalie Ngoi, Wen Yee Chay, Kidong Kim, David S.P. Tan, Samuel Ow, Valerie Heong, Veonice Bijin Au, Chel Hun Choi
Publikováno v:
International Journal of Gynecological Cancer
BackgroundThe optimal treatment of recurrent ovarian clear cell carcinoma remains unknown. There is increasing rationale to support the role of immune checkpoint inhibitors targeting the programmed cell death protein 1 (PD-1)/programmed death-ligand
Autor:
Jihye Kim, Tae-Joong Kim, Chel Hun Choi, Joon-Yong Chung, Jae Ryoung Hwang, Stephen M. Hewitt, Yoo-Young Lee, Byoung-Gie Kim, Jeong-Won Lee, Duk-Soo Bae
Publikováno v:
Journal of Clinical Medicine
Journal of Clinical Medicine, Vol 9, Iss 1137, p 1137 (2020)
Volume 9
Issue 4
Journal of Clinical Medicine, Vol 9, Iss 1137, p 1137 (2020)
Volume 9
Issue 4
Ovarian clear cell adenocarcinoma (Ov-CCA) has a higher prevalence in the Japanese ancestry than other populations. The ancestral disparities in Ov-CCA prevalence suggests the presence of Ov-CCA-specific genetic alterations and may provide an opportu
Publikováno v:
Obstetrics & Gynecology Science
Epithelial ovarian carcinoma is a high mortality neoplasm in gynecologic malignancy. It usually can metastasize to distant organs such as pleura, liver, lung, and lymph nodes. However, the skin metastases are not common and related to very poor progn
Publikováno v:
Poster exhibition Day 2.
Introduction/Background Activating PIK3CA mutations are described in one third of ovarian clear cell adenocarcinomas (OCCA), an endometriosis-associated cancer, and are likely early events its development. To better characterise PIK3CA-mutated OCCA,
Publikováno v:
Molecular Cancer, Vol 11, Iss 1, p 53 (2012)
Abstract Background This study is to analyze promoter methylation of various tumor suppressor genes in different types of ovarian carcinoma and to identify potential therapeutic targets of ovarian clear cell adenocarcinoma (OCCA). Materials and metho
Externí odkaz:
https://doaj.org/article/4879115ece0c4af88c4ca3768268a476
Publikováno v:
Medicine
Rationale: Ovarian malignancy is associated with one of the highest rates of death among gynecological reproductive system malignancies. While progress has been made in surgical and postoperative adjuvant treatment approaches, the early atypical clin
Autor:
Takashi Takeda, Moito Iijima, Kiyoko Umene, Kenta Masuda, Masataka Adachi, Ryuichiro Okawa, Haruko Kunitomi, Kanako Nakamura, Kouji Banno, Daisuke Aoki, Yusuke Kobayashi, Eiichiro Tominaga, Megumi Yanokura, Yuya Nogami, Miho Iida
Publikováno v:
Oncology Reports
The AT-rich interacting domain-containing protein 1A gene (ARID1A) encodes ARID1A, a member of the SWI/SNF chromatin remodeling complex. Mutation of ARID1A induces changes in expression of multiple genes (CDKN1A, SMAD3, MLH1 and PIK3IP1) via chromati