Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Ovanes Mekenyan"'
Autor:
Chanita Kuseva, Valentin Marinov, Todor Pavlov, Todor Petkov, Atanas Chapkanov, Detelina Dimitrova, Tobias Wombacher, Sarah Mullen-Hinkle, Wisdom Zhu, Michael Siebold, Ovanes Mekenyan
Publikováno v:
Computational Toxicology. 23:100230
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1bd70ccd8bdcd911e840f0f5e688c5b3
https://doi.org/10.1016/j.comtox.2022.100230
https://doi.org/10.1016/j.comtox.2022.100230
Autor:
Daniela Nedelcheva, Stoyanka Stoeva, Sabcho Dimitrov, Ann Detroyer, Aziz Fadli, Reine Note, Delphine Blanchet, Ovanes Mekenyan
Publikováno v:
Computational Toxicology. 12:100109
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e514a1064e9cd2fcd050e9d0012b2535
https://doi.org/10.1016/j.comtox.2019.100109
https://doi.org/10.1016/j.comtox.2019.100109
Publikováno v:
Alternatives to Laboratory Animals. 39:481-493
On 30 June 2011, the European Chemicals Agency published two reports, one on the functioning of the REACH system, the other on the use of alternatives to animal testing in compliance with that system. The data presented are based on information gaine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06f4faeef6fd4b4d930e7fac50dc93db
https://doi.org/10.1177/026119291103900509
https://doi.org/10.1177/026119291103900509
Autor:
Ed Thompson, Stefan Kotov, Nadezhda Dimitrova, John D. Walker, Rossitsa Serafimova, S. Dimitrov, Ovanes Mekenyan
Publikováno v:
Chemical Research in Toxicology. 17:753-766
Traditional attempts to model genotoxicity data have been limited to congeneric data sets, primarily because the mechanism of action was ignored, and frequently, the chemicals required metabolism to the active species. In this exercise, the COmmon RE
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0b69839211c0e23642778aad10ed9e8
https://doi.org/10.1021/tx030049t
https://doi.org/10.1021/tx030049t
Autor:
Ovanes Mekenyan
Publikováno v:
Current Pharmaceutical Design. 8:1605-1621
The basic principles of 3-D quantitative structure-activity relationships (QSARs) analysis are discussed in the light of the fuzzy logic concept. According to that concept, the traditionally one chemical - one structure - one parameter value relation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3703b0c8e2f091c021fed55440665645
https://doi.org/10.2174/1381612023394278
https://doi.org/10.2174/1381612023394278
Autor:
S. Imbert, Ann Detroyer, C. Piroird, Ovanes Mekenyan, Joan Eilstein, S. Dimitrov, Yordan H. Karakolev, Chanita Kuseva, Hristiana Ivanova, I. Popova
Publikováno v:
Toxicology Letters. 280:S289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::448789f53ef9125e03915bdcc487c0ed
https://doi.org/10.1016/j.toxlet.2017.07.812
https://doi.org/10.1016/j.toxlet.2017.07.812
Publikováno v:
Handbook of Metabolic Pathways of Xenobiotics
A wide range of industrial, agricultural, and consumer activities release into the environment chemical pollutants that do not readily break down and persist for a long range in the environment (P), are not easily metabolized and can bioaccumulate in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c75b75455bf32961fda0086571308301
https://doi.org/10.1002/9781118541203.xen0035
https://doi.org/10.1002/9781118541203.xen0035
Publikováno v:
Environmental Toxicology and Chemistry. 19:1727-1740
A structure–activity relationship evaluation of alkylphenol activation of a human estrogen receptor (hER) reporter gene construct was done using the Common Reactivity Pattern approach. Energetically reasonable conformer distributions for selected s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4977642a12709c9e633474fa13583ff5
https://doi.org/10.1002/etc.5620190705
https://doi.org/10.1002/etc.5620190705
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 930
Computer-based representation of chemicals makes it possible to organize data in chemical databases-collections of chemical structures and associated properties. Databases are widely used wherever efficient processing of chemical information is neede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c9ad4f41c2bb00e7d66858e692b38e47
https://pubmed.ncbi.nlm.nih.gov/23086836
https://pubmed.ncbi.nlm.nih.gov/23086836
Autor:
Stephanie Ringeissen, Laurent Marrot, Reine Note, Anita Labarussiat, Stéphane Imbert, Milen Todorov, Ovanes Mekenyan, Jean-Roch Meunier
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 25(1)
Phototoxicity is of increasing concern in dermatology, since modern lifestyle is often associated with exposure to sunlight. The most commonly reported process is via oxidative reactions. Therefore characterizing the "photo-pro-oxidant" potential of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd0b5d52a5eaa7711323721d527898e7
https://pubmed.ncbi.nlm.nih.gov/20932893
https://pubmed.ncbi.nlm.nih.gov/20932893