In vivo single-particle imaging of nuclear mRNA export in budding yeast demonstrates an essential role for Mex67p

Autor: Smith, Carlas, Lari, Azra, Derrer, Carina Patrizia, Ouwehand, Anette, Rossouw, Ammeret, Huisman, Maximiliaan, Dange, Thomas, Hopman, Mark, Joseph, Aviva, Zenklusen, Daniel, Weis, Karsten, Grunwald, David, Montpetit, Ben

Publikováno v: The Journal of cell biology, vol 211, iss 6

Many messenger RNA export proteins have been identified; yet the spatial and temporal activities of these proteins and how they determine directionality of messenger ribonucleoprotein (mRNP) complex export from the nucleus remain largely undefined. H

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https://escholarship.org/uc/item/7hv837hf

In vivo single-particle imaging of nuclear mRNA export in budding yeast demonstrates an essential role for Mex67p.

Autor: Smith C; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605 Department Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605., Lari A; Department of Cell Biology, University of Alberta, T6G 2H7 Edmonton, Alberta, Canada., Derrer CP; Department of Biology, Institute of Biochemistry, ETH Zurich, 8093 Zurich, Switzerland., Ouwehand A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605 Department Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands., Rossouw A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605 Department Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands., Huisman M; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605 Department Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands., Dange T; Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands., Hopman M; Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands., Joseph A; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605 Department Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605., Zenklusen D; Departement de Biochimie et Medecine Moleculaire, Universite de Montreal, H3T 1J4 Montreal, Quebec, Canada., Weis K; Department of Biology, Institute of Biochemistry, ETH Zurich, 8093 Zurich, Switzerland Department of Cell and Developmental Biology, University of California, Berkeley, Berkeley, CA 94720 ben.montpetit@ualberta.ca david.grunwald@umassmed.edu karsten.weis@bc.biol.ethz.ch., Grunwald D; RNA Therapeutics Institute, University of Massachusetts Medical School, Worcester, MA 01605 Department Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605 Bionanoscience, Kavli Institute of Nanoscience, Delft University of Technology, 2628 CJ Delft, Netherlands ben.montpetit@ualberta.ca david.grunwald@umassmed.edu karsten.weis@bc.biol.ethz.ch., Montpetit B; Department of Cell Biology, University of Alberta, T6G 2H7 Edmonton, Alberta, Canada ben.montpetit@ualberta.ca david.grunwald@umassmed.edu karsten.weis@bc.biol.ethz.ch.

Publikováno v: The Journal of cell biology [J Cell Biol] 2015 Dec 21; Vol. 211 (6), pp. 1121-30.