Recent applications of seven-membered rings in drug design.

Autor: Ouvry G; Evotec (U.K.) Ltd., 114 Innovation Drive, Milton Park, Abingdon, Oxfordshire OX14 4RZ, UK.

Publikováno v: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2022 Mar 01; Vol. 57, pp. 116650. Date of Electronic Publication: 2022 Jan 31.

Novel library synthesis of 3,4-disubstituted pyridin-2(1 H )-ones via cleavage of pyridine-2-oxy-7-azabenzotriazole ethers under ionic hydrogenation conditions at room temperature.

Autor: Pierre R; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Brethon A; Edelris, 60, Avenue Rockefeller, Bioparc, Bioserra 1 Building, 69008 Lyon, France., Jacques SA; Edelris, 60, Avenue Rockefeller, Bioparc, Bioserra 1 Building, 69008 Lyon, France., Blond A; Edelris, 60, Avenue Rockefeller, Bioparc, Bioserra 1 Building, 69008 Lyon, France., Chambon S; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Talano S; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Raffin C; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Musicki B; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Bouix-Peter C; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Tomas L; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Ouvry G; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Morgentin R; Edelris, 60, Avenue Rockefeller, Bioparc, Bioserra 1 Building, 69008 Lyon, France., Hennequin LF; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland., Harris CS; Galderma SA, Rue d'Entre-deux-Villes 10, 1814 Vevey, Switzerland.

Publikováno v: Beilstein journal of organic chemistry [Beilstein J Org Chem] 2021 Jan 18; Vol. 17, pp. 156-165. Date of Electronic Publication: 2021 Jan 18 (Print Publication: 2021).

LB1578 Identification and characterization of highly optimized RORγ inverse agonists for the topical treatment of psoriasis

Autor: Hervouet, C., Bihl, F., Ouvry, G., Musicki, B., Harris, C., Bouix-peter, C., Pascau, J., Chaussade, C., Piwnica, D., Deret, S., Julia, V., Hennequin, L., Vial, E., Hacini-Rachinel, F.

Publikováno v: In Journal of Investigative Dermatology September 2018 138(9):B19-B19

Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors.

Autor: Ouvry G; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Clary L; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Tomas L; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Aurelly M; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Bonnary L; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Borde E; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Bouix-Peter C; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Chantalat L; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Defoin-Platel C; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Deret S; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Forissier M; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Harris CS; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Isabet T; Synchrotron Soleil, L'Orme des Merisiers, Saint-Aubin - BP 48, 91192 Gif-sur-Yvette Cedex, France., Lamy L; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Luzy AP; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Pascau J; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Soulet C; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Taddei A; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Taquet N; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Thoreau E; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Varvier E; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Vial E; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France., Hennequin LF; Nestlé Skin Health R&D, 2400 Route des colles, BP 87, 06902 Sophia-Antipolis Cedex, France.

Publikováno v: ACS medicinal chemistry letters [ACS Med Chem Lett] 2019 Oct 04; Vol. 10 (11), pp. 1561-1567. Date of Electronic Publication: 2019 Oct 04 (Print Publication: 2019).

A New Radical Allylation Reaction

Autor: Zard, Samir, Ouvry, G., Quiclet-Sire, Béatrice

Publikováno v: Angewandte Chemie International Edition
Angewandte Chemie International Edition, Wiley-VCH Verlag, 2006, 45, pp.5002-5006

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ffc7beadb0a562dc10a8b6d1215a6769
https://hal.archives-ouvertes.fr/hal-00101564