Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Outi Simola"'
Autor:
Kim Wong, Federico Abascal, Latasha Ludwig, Heike Aupperle-Lellbach, Julia Grassinger, Colin W. Wright, Simon J. Allison, Emma Pinder, Roger M. Phillips, Laura P. Romero, Arnon Gal, Patrick J. Roady, Isabel Pires, Franco Guscetti, John S. Munday, Maria C. Peleteiro, Carlos A. Pinto, Tânia Carvalho, João Cota, Elizabeth C. Du Plessis, Fernando Constantino-Casas, Stephanie Plog, Lars Moe, Simone de Brot, Ingrid Bemelmans, Renée Laufer Amorim, Smitha R. Georgy, Justina Prada, Jorge del Pozo, Marianne Heimann, Louisiane de Carvalho Nunes, Outi Simola, Paolo Pazzi, Johan Steyl, Rodrigo Ubukata, Peter Vajdovich, Simon L. Priestnall, Alejandro Suárez-Bonnet, Franco Roperto, Francesca Millanta, Chiara Palmieri, Ana L. Ortiz, Claudio S. L. Barros, Aldo Gava, Minna E. Söderström, Marie O’Donnell, Robert Klopfleisch, Andrea Manrique-Rincón, Inigo Martincorena, Ingrid Ferreira, Mark J. Arends, Geoffrey A. Wood, David J. Adams, Louise van der Weyden
Publikováno v:
Genome Biology, Vol 24, Iss 1, Pp 1-29 (2023)
Abstract Background In humans, muscle-invasive bladder cancer (MIBC) is highly aggressive and associated with a poor prognosis. With a high mutation load and large number of altered genes, strategies to delineate key driver events are necessary. Dogs
Externí odkaz:
https://doaj.org/article/7c66e401481649aaa960de808d382f15
Alpha-chloralose poisoning in cats in three Nordic countries - the importance of secondary poisoning
Autor:
Ulrika Windahl, Annica Tevell Åberg, Fedor Kryuchkov, Sandra Lundgren, Cecilia Tegner, Kristoffer Dreimanis, Sanna Koivisto, Outi Simola, Morten Sandvik, Aksel Bernhoft
Publikováno v:
BMC Veterinary Research, Vol 18, Iss 1, Pp 1-13 (2022)
Abstract Background Alpha-chloralose (AC) is a compound known to be toxic to various animal species and humans. In 2018 and 2019 an increase in suspected cases of AC poisoning in cats related to the use of AC as a rodenticide was reported to national
Externí odkaz:
https://doaj.org/article/80547c26c49d4f6e9bc5beb856e218a2
Autor:
Mari Karimaa, Reetta Riikonen, Henna Kettunen, Päivi Taavitsainen, Meri Ramela, Marcin Chrusciel, Stefan Karlsson, Petteri Rummakko, Outi Simola, Gerd Wohlfahrt, Pasi Hakulinen, Annamari Vuorela, Heikki Joensuu, Tapio Utriainen, Karim Fizazi, Riikka Oksala
Publikováno v:
Molecular Cancer Therapeutics. 21:1765-1776
Binding of steroid hormones to their cognate receptors regulates the growth of most prostate and breast cancers. We hypothesized that CYP11A inhibition might halt the synthesis of all steroid hormones, because CYP11A is the only enzyme that catalyses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff128fc8cd26b2430750a17250799c6a
https://doi.org/10.1158/1535-7163.mct-22-0115
https://doi.org/10.1158/1535-7163.mct-22-0115
Autor:
Riikka Oksala, Karim Fizazi, Tapio Utriainen, Heikki Joensuu, Annamari Vuorela, Pasi Hakulinen, Gerd Wohlfahrt, Outi Simola, Petteri Rummakko, Stefan Karlsson, Marcin Chrusciel, Meri Ramela, Päivi Taavitsainen, Henna Kettunen, Reetta Riikonen, Mari Karimaa
Supplementary Data from First-in-Class Small Molecule to Inhibit CYP11A1 and Steroid Hormone Biosynthesis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::46051e52dfa8aaf74a566175a5384ef4
https://doi.org/10.1158/1535-7163.22523826
https://doi.org/10.1158/1535-7163.22523826
Autor:
Ulrika Windahl, Annica Tevell Åberg, Fedor Kryuchov, Sandra Lundgren, Cecilia Tegner, Kristoffer Dreimanis, Sanna Koivisto, Outi Simola, Morten Sandvik, Aksel Bernhoft
Publikováno v:
TemaNord ISBN: 9789289374651
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fcc2a1fafa3c084b0ad5615e2837c393
https://doi.org/10.6027/temanord2022-565
https://doi.org/10.6027/temanord2022-565
Autor:
Annamari Vuorela, Petteri Rummakko, Karim Fizazi, Riikka Oksala, Päivi Taavitsainen, Marcin Chrusciel, Mari Karimaa, Suvi Mansikka-Savolainen, Henna Kettunen, Outi Simola, Meri Ramela, Gerd Wohlfahrt
Publikováno v:
Cancer Research. 81:1250-1250
Several new treatments have been developed to target the androgen signaling axis in CRPC over the last decade. Despite the new treatment options, the challenge for managing CRPC is the limited duration of clinical benefit from treatments due to prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e5f87cb99481938ff3775612c7dbef8
https://doi.org/10.1158/1538-7445.am2021-1250
https://doi.org/10.1158/1538-7445.am2021-1250
Autor:
Meri Ramela, Reetta Riikonen, Gerd Wohlfahrt, Riikka Oksala, Mari Karimaa, Pekka Kallio, Mika Mustonen, Pirjo Vehmaan-Kreula, Outi Simola, Petteri Rummakko
Publikováno v:
Annals of Oncology. 29:viii292
340 Background: Castration-resistant prostate cancer (CRPC) is a major cause of cancer mortality worldwide. The mechanisms behind the development of resistance are complex and not fully understood; altered androgen synthesis, androgen receptor (AR) o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b94bfcd365ac20ea7cca1613a3fed5b0
https://doi.org/10.1093/annonc/mdy284.044
https://doi.org/10.1093/annonc/mdy284.044