Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Outi R, Saramäki"'
Autor:
Tapio Visakorpi, Outi R. Saramäki, Teuvo L.J. Tammela, Ulf-Håkan Stenman, Hazel Bracken, Teemu T. Tolonen, Katri A. Leinonen
Supplementary Data from Association of SPINK1 Expression and TMPRSS2:ERG Fusion with Prognosis in Endocrine-Treated Prostate Cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::54aae61925c8d5f58ab54fe9bccba854
https://doi.org/10.1158/1078-0432.22442414
https://doi.org/10.1158/1078-0432.22442414
Autor:
Tapio Visakorpi, Outi R. Saramäki, Teuvo L.J. Tammela, Ulf-Håkan Stenman, Hazel Bracken, Teemu T. Tolonen, Katri A. Leinonen
Purpose: The aim of the study was to examine whether TMPRSS2:ERG fusion or SPINK1 protein expression is associated with hormone responsiveness of prostate cancer and can thus be used as a biomarker.Experimental Design: Diagnostic needle biopsies from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a52519a49de7b664e76cab1fa4d4c381
https://doi.org/10.1158/1078-0432.c.6519143
https://doi.org/10.1158/1078-0432.c.6519143
Autor:
Marije M. Vleugel, Reinhard Bos, Horst Buerger, Petra van der Groep, Outi R. Saramäki, Tapio Visakorpi, Elsken van der Wall, Paul J. van Diest
Publikováno v:
Cellular Oncology, Vol 26, Iss 5-6, Pp 347-351 (2004)
Objective: Hypoxia Inducible Factor‐1 (HIF‐1) is an important transcription factor that stimulates tumour growth and metastases via several pathways, including angiogenesis and altered metabolism. Activation of HIF‐1 depends on the levels of it
Externí odkaz:
https://doaj.org/article/c9521a692cea43abb3790c6e4dc3e66a
Autor:
Sanna Siltanen, Tiina Wahlfors, Martin Schindler, Outi R Saramäki, John Patrick Mpindi, Leena Latonen, Robert L Vessella, Teuvo L J Tammela, Olli Kallioniemi, Tapio Visakorpi, Johanna Schleutker
Publikováno v:
PLoS ONE, Vol 6, Iss 10, p e26595 (2011)
ARLTS1 is a recently characterized tumor suppressor gene at 13q14.3, a region frequently deleted in both sporadic and hereditary prostate cancer (PCa). ARLTS1 variants, especially Cys148Arg (T442C), increase susceptibility to different cancers, inclu
Externí odkaz:
https://doaj.org/article/1590925213ea4b3aa63622c9307f2430
Autor:
Katri A. Leinonen, Leena Latonen, Teemu Grönlund, Teuvo L.J. Tammela, Robert L. Vessella, Outi R. Saramäki, Tapio Visakorpi
Publikováno v:
Genes, Chromosomes and Cancer. 55:617-625
Amplification of the 9p13.3 chromosomal region occurs in a subset of prostate cancers (PCs); however, the target gene or genes of this amplification have remained unidentified. The aim of this study was to investigate the 9p13.3 amplification in more
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e5e7b1bf6dd4ff727a55d073dfeef91e
https://doi.org/10.1002/gcc.22364
https://doi.org/10.1002/gcc.22364
Autor:
Johannes Routila, Jukka Westermarck, Outi R. Saramäki, Sami Ventelä, Tapio Visakorpi, Turker Bilgen, Reidar Grénman
Publikováno v:
Journal of Oral Pathology and Medicine. 45(5):329-337
Background CIP2A, an inhibitor of PP2A tumour suppressor function, is a widely overexpressed biomarker of aggressive disease and poor therapy response in multiple human cancer types. Methods CIP2A and DPPA4 copy number alterations and expression were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29681b07a677be3fd02f740ae4e8ec37
https://doi.org/10.1111/jop.12372
https://doi.org/10.1111/jop.12372
Autor:
Liisa Sjöblom, Kirsi J. Granberg, Joonas Tuominen, Antti Ylipää, Robert L. Vessella, Matti Annala, Serdar Karakurt, Tapio Visakorpi, Teuvo L.J. Tammela, Kati Kivinummi, Kirsi M. Kaukoniemi, Matti Nykter, Outi R. Saramäki, Olli Yli-Harja, Leena Latonen, Wei Zhang, Pekka Ruusuvuori
Publikováno v:
Oncotarget
ResearcherID
Scopus-Elsevier
ResearcherID
Scopus-Elsevier
Prostate cancer is the third most common cause of male cancer death in developed countries, and one of the most comprehensively characterized human cancers. Roughly 60% of prostate cancers harbor gene fusions that juxtapose ETS-family transcription f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f14c1b7608b89d900fd226f6edfee574
https://doi.org/10.18632/oncotarget.3359
https://doi.org/10.18632/oncotarget.3359
Autor:
Inti Zlobec, Outi R. Saramäki, Diana Rotzer, George N. Thalmann, Tapio Visakorpi, Vera Genitsch, Roland Seiler, Achim Fleischmann
Publikováno v:
The Prostate. 74:1647-1654
BACKGROUND TMPRSS2-ERG gene fusion is the most frequent genetic alteration in prostate cancer. However, information about its distribution in lymph node positive prostate cancers and the prognostic significance in these advanced tumors is unknown. ME
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ab9a430a03da7445c5ea94c8b12f20f8
https://doi.org/10.1002/pros.22882
https://doi.org/10.1002/pros.22882
Autor:
Matti Nykter, Takahiro Kimura, G. Steven Bova, Teuvo L.J. Tammela, Sung Ho Hahm, Bungo Furusato, Outi R. Saramäki, Kerri Keiger, William B. Isaacs, Katri A. Leinonen, Tapio Visakorpi, Hiroyoshi Suzuki, Hiroyuki Takahashi, Shin Egawa, Teemu Tolonen, Ulf-Håkan Stenman
Publikováno v:
Cancer Epidemiology, Biomarkers & Prevention. 22:2333-2344
Background: The associations of ERG overexpression with clinical behavior and molecular pathways of prostate cancer are incompletely known. We assessed the association of ERG expression with AR, PTEN, SPINK1, Ki-67, and EZH2 expression levels, deleti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90fc68fba795a1ab7f982a5d9e8fe45f
https://doi.org/10.1158/1055-9965.epi-13-0333-t
https://doi.org/10.1158/1055-9965.epi-13-0333-t
Autor:
Hans Lilja, Tapio Visakorpi, Matti Nykter, Teemu Tolonen, Teuvo L.J. Tammela, Johanna Schleutker, Janika Nättinen, Outi R. Saramäki, Liisa Sjöblom, Katri A. Leinonen, G. Steven Bova, Matti Annala, Tiina Wahlfors
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0150241 (2016)
PLoS ONE
PLoS ONE
Microseminoprotein-beta (MSMB, MSMB) is an abundant secretory protein contributed by the prostate, and is implicated as a prostate cancer (PC) biomarker based on observations of its lower expression in cancerous cells compared with benign prostate ep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e2517c0d303ea7b2efc944b0b444ff6
http://juuli.fi/Record/0254805616
http://juuli.fi/Record/0254805616