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pro vyhledávání: '"Outi Meriläinen"'
Autor:
Outi Meriläinen
Publikováno v:
Informaatiotutkimus, Vol 15, Iss 3 (2008)
Externí odkaz:
https://doaj.org/article/c967ab69e9a64a37a09fedca0023f432
Autor:
Outi Meriläinen
Publikováno v:
Informaatiotutkimus
Informaatiotutkimus, Vol 15, Iss 3 (2008)
Informaatiotutkimus, Vol 15, Iss 3 (2008)
Publikováno v:
International Journal of Oncology.
Protein transduction domain (PTD) from HIV-1 TAT protein has been reported to translocate across the mammalian cell membrane, also as a part of fusion proteins. However, the true nature of TAT-mediated intercellular spreading is still under debate be
Autor:
Tanja Hakkarainen, Tiina Wahlfors, Outi Meriläinen, Sami Loimas, Akseli Hemminki, Jarmo Wahlfors
Publikováno v:
The journal of gene medicine. 7(7)
VP22 is a herpes simplex virus type 1 (HSV-1) tegument protein that has been suggested to spread from cell to cell, alone or as a part of fusion proteins. Creating controversy, some reports indicate that VP22 cannot facilitate significant intercellul
Autor:
Tiina Pasanen, Esko Alhava, Anni Tenhunen, Ann-Marie Määttä, Riikka Pellinen, Kimmo Mäkinen, Outi Meriläinen, Jarmo Wahlfors
Publikováno v:
International Journal of Oncology.
Lung cancer is a group of diseases that are difficult to cure and new treatment modalities, like gene therapy are actively tested to find alternatives for currently used strategies. Herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) metho
Autor:
Ann-Marie, Määttä, Anni, Tenhunen, Tiina, Pasanen, Outi, Meriläinen, Riikka, Pellinen, Kimmo, Mäkinen, Esko, Alhava, Jarmo, Wahlfors
Publikováno v:
International journal of oncology. 24(4)
Lung cancer is a group of diseases that are difficult to cure and new treatment modalities, like gene therapy are actively tested to find alternatives for currently used strategies. Herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) metho
Publikováno v:
Molecular Therapy. 9:S227-S228
Top of pageAbstract INTRODUCTION Suicide gene therapy using herpes simplex thymidine kinase gene combined to prodrug ganciclovir (GCV) is one of the most prominent approaches in cancer gene therapy. However, efficacy of the therapy is often insuffici
Autor:
Tanja Hakkarainen, Riikka Pellinen, Elisa Vähäkangas, Katja Häkkinen, Ari Hinkkanen, Jarmo Wahlfors, Tuula Salonen, Saara Lehmusvaara, Ilkka Julkunen, Kari J. Airenne, Outi Meriläinen
Publikováno v:
Molecular Therapy. 11:S40
The first line of defense that gene delivery vectors, viral or non-viral, confront in cells is the type I interferon (IFN) response. Cells produce type I IFNs as a response to dsRNA (intermediates of viral replication) and other viral components. IFN
Publikováno v:
Molecular Therapy. 11:S189
Polycations have been used to enhance virus mediated gene transfer. Recently Gratton et al. (Nat. Med. 9, 357-362, 2003) demonstrated that certain polypeptides can also be used to improve retro- and adenoviral gene transfer. To verify whether this ca