Zobrazeno 1 - 10
of 131
pro vyhledávání: '"Outi Kilpivaara"'
Autor:
Panagiotis Baliakas, Bianca Tesi, Jörg Cammenga, Asbjørg Stray‐Pedersen, Kirsi Jahnukainen, Mette Klarskov Andersen, Helena Ågerstam, Maria Creignou, Ingunn Dybedal, Klas Raaschou‐Jensen, Kirsten Grønbæk, Outi Kilpivaara, Eva Hellström Lindberg, Ulla Wartiovaara‐Kautto
Publikováno v:
HemaSphere, Vol 8, Iss 8, Pp n/a-n/a (2024)
Abstract Increasing recognition of germline DDX41 variants in patients with hematological malignancies prompted us to provide DDX41‐specific recommendations for diagnosis, surveillance, and treatment. Causative germline variants in the DDX41 predis
Externí odkaz:
https://doaj.org/article/48ac9b34b8014e978388be0b40d5d24b
Autor:
Atte K Lahtinen, Jessica Koski, Jarmo Ritari, Kati Hyvärinen, Satu Koskela, Jukka Partanen, Kim Vettenranta, Minna Koskenvuo, Riitta Niittyvuopio, Urpu Salmenniemi, Maija Itälä-Remes, Kirsi Jahnukainen, Outi Kilpivaara, Ulla Wartiovaara- Kautto, Maarja Karu
Publikováno v:
EJC Paediatric Oncology, Vol 2, Iss , Pp 100058- (2023)
Externí odkaz:
https://doaj.org/article/00460f5941584e5d97b84798c1738c14
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 44, Iss , Pp 100933- (2023)
Different sources of mutagenesis cause consistently identifiable patterns of mutations and mutational signatures that mirror the various carcinogenetic processes. We used publicly available data from the Cancer Genome Atlas to evaluate the associatio
Externí odkaz:
https://doaj.org/article/d01b28bbb0d94482abdf40baced304e6
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionComplement system has a postulated role in endothelial problems after hematopoietic stem cell transplantation (HSCT). In this retrospective, singlecenter study we studied genetic complement system variants in patients with documented endo
Externí odkaz:
https://doaj.org/article/d5ae5beaa7d1483a948629a26118cbb0
Autor:
Marja Hakkarainen, Jessica R. Koski, Caroline A. Heckman, Pekka Anttila, Raija Silvennoinen, Juha Lievonen, Outi Kilpivaara, Ulla Wartiovaara‐Kautto
Publikováno v:
eJHaem, Vol 3, Iss 4, Pp 1352-1357 (2022)
Abstract Observations of inherited susceptibility to multiple myeloma have led to active research in defining predisposing genes to the disease. Here, we analysed 128 plasma cell dyscrasia patients’ germline whole‐exome sequencing data. Rare domi
Externí odkaz:
https://doaj.org/article/2c12cac227bf47e280d6d74f3b53ad94
Autor:
Laura Langohr, Ilse Kaaja, Suvi Douglas, Tuulia Räisänen, Sadiksha Adhikari, Markus Vähä-Koskela, Caroline Heckman, Jenni Lahtela, Ulla Wartiovaara-Kautto, Esa Pitkänen, Outi Kilpivaara
Publikováno v:
HemaSphere, Vol 7, p e8517818 (2023)
Externí odkaz:
https://doaj.org/article/708260efd88a41cea3e25e302d29c906
Autor:
Suvi P. M. Douglas, Atte K. Lahtinen, Jessica R. Koski, Lilli Leimi, Mikko A. I. Keränen, Minna Koskenvuo, Caroline A. Heckman, Kirsi Jahnukainen, Esa Pitkänen, Ulla Wartiovaara-Kautto, Outi Kilpivaara
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Despite recent progress in acute lymphoblastic leukemia (ALL) therapies, a significant subset of adult and pediatric ALL patients has a dismal prognosis. Better understanding of leukemogenesis and recognition of germline genetic changes may
Externí odkaz:
https://doaj.org/article/65565a374821414dab854c43e940b4e9
Autor:
Tatiana Cajuso, Päivi Sulo, Tomas Tanskanen, Riku Katainen, Aurora Taira, Ulrika A. Hänninen, Johanna Kondelin, Linda Forsström, Niko Välimäki, Mervi Aavikko, Eevi Kaasinen, Ari Ristimäki, Selja Koskensalo, Anna Lepistö, Laura Renkonen-Sinisalo, Toni Seppälä, Teijo Kuopio, Jan Böhm, Jukka-Pekka Mecklin, Outi Kilpivaara, Esa Pitkänen, Kimmo Palin, Lauri A. Aaltonen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-9 (2019)
Retrotransposons are usually dormant in healthy tissue, but become activated during malignancy. Here, in colorectal cancer, Cajuso et al. show that retrotransposon activity associates with clinical features of the disease.
Externí odkaz:
https://doaj.org/article/0b6a406f2deb41ea96cf45072af0e221
Autor:
Eevi Kaasinen, Outi Kuismin, Kristiina Rajamäki, Heikki Ristolainen, Mervi Aavikko, Johanna Kondelin, Silva Saarinen, Davide G. Berta, Riku Katainen, Elina A. M. Hirvonen, Auli Karhu, Aurora Taira, Tomas Tanskanen, Amjad Alkodsi, Minna Taipale, Ekaterina Morgunova, Kaarle Franssila, Rainer Lehtonen, Markus Mäkinen, Kristiina Aittomäki, Aarno Palotie, Mitja I. Kurki, Olli Pietiläinen, Morgane Hilpert, Elmo Saarentaus, Jaakko Niinimäki, Juhani Junttila, Kari Kaikkonen, Pia Vahteristo, Radek C. Skoda, Mikko R. J. Seppänen, Kari K. Eklund, Jussi Taipale, Outi Kilpivaara, Lauri A. Aaltonen
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-17 (2019)
Somatic heterozygous TET2 loss drives clonal hematopoiesis, which is linked to malignant cell degeneration and potentially cardiovascular disease. Here, the authors investigate the molecular impact of a germline TET2 mutation in a lymphoma family, fi
Externí odkaz:
https://doaj.org/article/46989eed5d5545f397b38c9c2843f70f
Autor:
Kaitlyn Shank, Andrew Dunbar, Priya Koppikar, Maria Kleppe, Julie Teruya-Feldstein, Isabelle Csete, Neha Bhagwat, Matthew Keller, Outi Kilpivaara, Franziska Michor, Ross L. Levine, Laura de Vargas Roditi
Publikováno v:
Haematologica, Vol 105, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/b852f2a330984500a123c63a4c33e7a4