Maintenance of bacterial outer membrane lipid asymmetry: insight into MlaA

Autor: M. Kaur, M.-P. Mingeot -Leclercq

Publikováno v: BMC Microbiology, Vol 24, Iss 1, Pp 1-14 (2024)

Abstract The outer membrane (OM) of Gram-negative bacteria acts as an effective barrier to protect against toxic compounds. By nature, the OM is asymmetric with the highly packed lipopolysaccharide (LPS) at the outer leaflet and glycerophospholipids

Externí odkaz: https://doaj.org/article/03d079935e874984a7d95ef4546ee6d8

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The phospholipid-repair system LplT/Aas in Gram-negative bacteria protects the bacterial membrane envelope from host phospholipase A 2 attack.

Autor: Lin Y; From the Center for Membrane Biology, Department of Biochemistry and Molecular Biology and., Bogdanov M; the Departments of Biochemistry and Molecular Biology and., Lu S; From the Center for Membrane Biology, Department of Biochemistry and Molecular Biology and., Guan Z; the Department of Biochemistry, Duke University School of Medicine, Durham, North Carolina 27710, and., Margolin W; Microbiology and Molecular Genetics, University of Texas McGovern Medical School, Houston, Texas 77030., Weiss J; the Inflammation Program and Departments of Internal Medicine and Microbiology, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242., Zheng L; From the Center for Membrane Biology, Department of Biochemistry and Molecular Biology and lei.zheng@uth.tmc.edu.

Publikováno v: The Journal of biological chemistry [J Biol Chem] 2018 Mar 02; Vol. 293 (9), pp. 3386-3398. Date of Electronic Publication: 2018 Jan 18.