Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Oussama Abchir"'
Autor:
Khalid Chebbac, Oussama Abchir, Mohammed Chalkha, Abdelfattah El Moussaoui, Azeddin El Barnossi, Soufyane Lafraxo, Samir Chtita, Ahmad Mohammad Salamatullah, Mohammed Bourhia, Musaab Dauelbait, Samir Ibenmoussa, Zineb Benziane Ouaritini, Raja Guemmouh
Publikováno v:
CyTA - Journal of Food, Vol 22, Iss 1 (2024)
In the present work, we assessed the antioxidant, antibacterial, and antifungal activities of chemically defined Artemisia mesatlantica Maire (EOAM) essential oils. The GC-MS analysis of EOAM showed the presence of active promising active compounds.
Externí odkaz:
https://doaj.org/article/5871dc29f3c44ac79100e34106359b1e
Autor:
Nedjla Khelfa, Salah Belaidi, Oussama Abchir, Imane Yamari, Samir Chtita, Abdelouahid Samadi, Muneerah Mogren Al-Mogren, Majdi Hochlaf
Publikováno v:
Scientific African, Vol 24, Iss , Pp e02202- (2024)
Plasmodium falciparum dihydrofolate reductase (PfDHFR) is a promising therapeutic target for antimalarial interventions. Diaminodihydrotriazine derivatives have demonstrated their efficacy as antimalarial agents by targeting PfDHFR inhibition. In thi
Externí odkaz:
https://doaj.org/article/ab45d1614d5e4ab2a876b2e531f99ecc
Autor:
Marwa Manachou, Ossama Daoui, Oussama Abchir, Rahma Dahmani, Souad Elkhattabi, Abdelouahid Samadi, Salah Belaidi, Samir Chtita
Publikováno v:
Scientific African, Vol 23, Iss , Pp e02078- (2024)
Merging Density Functional Theory (DFT) with the Quantitative Structure-Activity Relationship (2D/3D-QSAR) modeling represents a promising avenue for exploring antibacterial activity and discovering potential drugs effective against both gram-positiv
Externí odkaz:
https://doaj.org/article/b6557d26bc8f4ab880b72795395ae46f
Autor:
Imane Yamari, Oussama Abchir, Farhan Siddique, Hanane Zaki, Abdelkbir Errougui, Mohammed Talbi, Mohammed Bouachrine, M'hammed ElKouali, Samir Chtita
Publikováno v:
Scientific African, Vol 23, Iss , Pp e01986- (2024)
Lippia Alba, a plant commonly utilized in traditional folk medicine, particularly in Brazil, is renowned for its essential oil possessing anti-inflammatory, antibacterial, anesthetic, and antiviral properties. In this study, we conducted molecular an
Externí odkaz:
https://doaj.org/article/c8ad5e06319241cd98ca27c59b567810
Autor:
Imane Yamari, Oussama Abchir, Hassan Nour, Meriem Khedraoui, Bouchra Rossafi, Abdelkbir Errougui, Mohammed Talbi, Abdelouahid Samadi, MHammed El Kouali, Samir Chtita
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 886 (2024)
Candida albicans and Aspergillus fumigatus are recognized as significant fungal pathogens, responsible for various human infections. The rapid emergence of drug-resistant strains among these fungi requires the identification and development of innova
Externí odkaz:
https://doaj.org/article/a2a8b695a815431981f09946be22d73a
Autor:
Meriem Khedraoui, Oussama Abchir, Hassan Nour, Imane Yamari, Abdelkbir Errougui, Abdelouahid Samadi, Samir Chtita
Publikováno v:
Pharmaceuticals, Vol 17, Iss 7, p 830 (2024)
Acetylcholinesterase (AChE) is one of the main drug targets for treating Alzheimer’s disease. This current study relies on multiple molecular modeling approaches to develop new potent inhibitors of AChE. We explored a 2D QSAR study using the statis
Externí odkaz:
https://doaj.org/article/c00fe19394ff443cb34ebc70bf5b8b8d
Autor:
Oussama Abchir, Meriem Khedraoui, Imane Yamari, Hassan Nour, Abdelkbir Errougui, Abdelouahid Samadi, Samir Chtita
Publikováno v:
PLoS ONE, Vol 19, Iss 9, p e0308308 (2024)
BackgroundThe increasing prevalence of diabetes and the side effects associated with current medications necessitate the development of novel candidate drugs targeting alpha-glucosidase as a potential treatment option.MethodsThis study employed compu
Externí odkaz:
https://doaj.org/article/e66078124efb4f0697ea528c611cb402
Autor:
Meriem Khedraoui, Hassan Nour, Imane Yamari, Oussama Abchir, Abdelkbir Errougui, Samir Chtita
Publikováno v:
Chemical Physics Impact, Vol 7, Iss , Pp 100361- (2023)
A series of 32 molecules derived from 7-prenyloxy-2,3-dihydroflavanone and 5‑hydroxy-7-prenyloxy-2,3-dihydro-flavanone possessing an inhibitory activity against the Acetylcholinesterase (AChE) enzyme were studied using the structure-activity (QSAR)
Externí odkaz:
https://doaj.org/article/276b9169f3d34ac58be2e348a88782ec
Autor:
Oussama Abchir, Ossama Daoui, Hassan Nour, Imane Yamari, Souad Elkhattabi, Abdelkbir Errougui, Samir Chtita
Publikováno v:
Scientific African, Vol 21, Iss , Pp e01745- (2023)
Diabetes Mellitus is one of the deadliest diseases in the world, while the current medications against this disease like acarbose represent many side effects such as diarrhea and abdominal discomfort. Many studies based on natural plants used in trad
Externí odkaz:
https://doaj.org/article/98df3d1664924ba0be9e6d7c57f2d300
Autor:
Imane Yamari, Oussama Abchir, Suraj N. Mali, Abdelkbir Errougui, Mohammed Talbi, Mhammed El Kouali, Samir Chtita
Publikováno v:
Scientific African, Vol 21, Iss , Pp e01754- (2023)
Originating in Wuhan, the COVID-19 pandemic wave has had a profound impact on the global healthcare system. In this study, we used a 2D QSAR technique, ADMET analysis, molecular docking, and dynamic simulations to sort and evaluate the performance of
Externí odkaz:
https://doaj.org/article/3c8a1261067c42c89f51ceb335207261