Zobrazeno 1 - 10
of 170
pro vyhledávání: '"Ousmane H"'
Autor:
Zachary Paul Billman, Stephen Bela Kovacs, Bo Wei, Kidong Kang, Ousmane H Cissé, Edward A Miao
Publikováno v:
eLife, Vol 12 (2024)
Gasdermins oligomerize to form pores in the cell membrane, causing regulated lytic cell death called pyroptosis. Mammals encode five gasdermins that can trigger pyroptosis: GSDMA, B, C, D, and E. Caspase and granzyme proteases cleave the linker regio
Externí odkaz:
https://doaj.org/article/0556709f95884b23904aa570a9334d9f
Autor:
Ousmane H. Cissé, Shelly J. Curran, H. Diego Folco, Yueqin Liu, Lisa Bishop, Honghui Wang, Elizabeth R. Fischer, A. Sally Davis, Christian Combs, Sabrina Thapar, John P. Dekker, Shiv Grewal, Melanie Cushion, Liang Ma, Joseph A. Kovacs
Publikováno v:
mBio, Vol 15, Iss 3 (2024)
ABSTRACT Centromeres are constricted chromosomal regions that are essential for cell division. In eukaryotes, centromeres display a remarkable architectural and genetic diversity. The basis of centromere-accelerated evolution remains elusive. Here, w
Externí odkaz:
https://doaj.org/article/b90416d035844a13812402c4d792a37f
Autor:
Liang Ma, Isabella Lin, Summer T. Hunter, Barbara Blasi, Patrizia Danesi, Christiane Weissenbacher-Lang, Ousmane H. Cisse, Jamie L. Rothenburger, Joseph A. Kovacs
Publikováno v:
Journal of Fungi, Vol 10, Iss 5, p 355 (2024)
Despite its ubiquitous infectivity to mammals with strong host specificity, our current knowledge about Pneumocystis has originated from studies of merely 4% of extant mammalian species. Further studies of Pneumocystis epidemiology across a broader r
Externí odkaz:
https://doaj.org/article/2dd0cc5306db473f8147eca109d5ed37
Autor:
Emily L. Coffey, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Katie M. Minor, Antti Sukura, Patrizia Danesi, Steven G. Friedenberg, Jonah N. Cullen, Christiane Weissenbacher-Lang, Julie C. Nadeau, Amber M. Graham, Martin N. Granick, Natalie K. Branson, Kyle C. Branson, Barbara Blasi, Casandra M. Jacobs, Eva Furrow
Publikováno v:
Journal of Fungi, Vol 10, Iss 3, p 198 (2024)
Pet dogs are a valuable natural animal model for studying relationships between primary immunodeficiencies and susceptibility to Pneumocystis and other opportunistic respiratory pathogens. Certain breeds, such as the Cavalier King Charles Spaniel, ar
Externí odkaz:
https://doaj.org/article/ef1fcb60af49463f86b4803ae34b6116
Autor:
Ousmane H. Cissé, Liang Ma, John P. Dekker, Pavel P. Khil, Jung-Ho Youn, Jason M. Brenchley, Robert Blair, Bapi Pahar, Magali Chabé, Koen K. A. Van Rompay, Rebekah Keesler, Antti Sukura, Vanessa Hirsch, Geetha Kutty, Yueqin Liu, Li Peng, Jie Chen, Jun Song, Christiane Weissenbacher-Lang, Jie Xu, Nathan S. Upham, Jason E. Stajich, Christina A. Cuomo, Melanie T. Cushion, Joseph A. Kovacs
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-14 (2021)
Cissé, Ma et al. utilize genomic data from Pneumocystis species infecting macaques, rabbit, dogs and rats to investigate the molecular basis of host specificity in Pneumocystis. Their analyses provide insight to the specific adaptations enabling the
Externí odkaz:
https://doaj.org/article/907c65fcc47a4c35b7cdbbac023e26da
Autor:
Christiane Weissenbacher-Lang, Barbara Blasi, Patricia Bauer, Diana Binanti, Karin Bittermann, Lara Ergin, Carmen Högler, Tanja Högler, Magdalena Klier, Julia Matt, Nora Nedorost, Serenella Silvestri, Daniela Stixenberger, Liang Ma, Ousmane H. Cissé, Joseph A. Kovacs, Amélie Desvars-Larrive, Annika Posautz, Herbert Weissenböck
Publikováno v:
Journal of Fungi, Vol 9, Iss 2, p 220 (2023)
Pneumocystis spp. are thought to adapt to the lungs of potentially all mammals. However, the full host range, fungal burden and severity of infection are unknown for many species. In this study, lung tissue samples originating from 845 animals of 31
Externí odkaz:
https://doaj.org/article/9d0ec7b4df5340d099c45c1743f0d1a2
Autor:
Ousmane H. Cissé, Jason E. Stajich
Publikováno v:
BMC Bioinformatics, Vol 20, Iss 1, Pp 1-9 (2019)
Abstract Background Inexpensive high-throughput DNA sequencing has democratized access to genetic information for most organisms so that research utilizing a genome or transcriptome of an organism is not limited to model systems. However, the quality
Externí odkaz:
https://doaj.org/article/d44eceb03deb49df836d01af4be1e3f3
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Environmental exposure has a significant impact on human health. While some airborne fungi can cause life-threatening infections, the impact of environment on fungal spore dispersal and transmission is poorly understood. The democratization
Externí odkaz:
https://doaj.org/article/da0829b7a1524354a2397abf9e69ef7d
Autor:
Liang Ma, Zehua Chen, Da Wei Huang, Ousmane H. Cissé, Jamie L. Rothenburger, Alice Latinne, Lisa Bishop, Robert Blair, Jason M. Brenchley, Magali Chabé, Xilong Deng, Vanessa Hirsch, Rebekah Keesler, Geetha Kutty, Yueqin Liu, Daniel Margolis, Serge Morand, Bapi Pahar, Li Peng, Koen K. A. Van Rompay, Xiaohong Song, Jun Song, Antti Sukura, Sabrina Thapar, Honghui Wang, Christiane Weissenbacher-Lang, Jie Xu, Chao-Hung Lee, Claire Jardine, Richard A. Lempicki, Melanie T. Cushion, Christina A. Cuomo, Joseph A. Kovacs
Publikováno v:
mBio, Vol 11, Iss 2 (2020)
ABSTRACT Pneumocystis, a major opportunistic pathogen in patients with a broad range of immunodeficiencies, contains abundant surface proteins encoded by a multicopy gene family, termed the major surface glycoprotein (Msg) gene superfamily. This supe
Externí odkaz:
https://doaj.org/article/506cf3cdb75d42c089e62b4f90d2fba5
Autor:
Barbara Blasi, Wolfgang Sipos, Christian Knecht, Sophie Dürlinger, Liang Ma, Ousmane H. Cissé, Nora Nedorost, Julia Matt, Herbert Weissenböck, Christiane Weissenbacher-Lang
Publikováno v:
Journal of Fungi, Vol 8, Iss 1, p 43 (2021)
While Pneumocystis has been recognized as both a ubiquitous commensal fungus in immunocompetent mammalian hosts and a major opportunistic pathogen in humans responsible for severe pneumonias in immunocompromised patients, in pigs its epidemiology and
Externí odkaz:
https://doaj.org/article/55c08f89ae474971bbb4fea7bc052343