Zobrazeno 1 - 10
of 110
pro vyhledávání: '"Ousheng, Liu"'
Publikováno v:
Systematic Reviews, Vol 13, Iss 1, Pp 1-15 (2024)
Abstract Background Fibrosis is the ultimate, common pathological ending of most chronic inflammatory diseases and increases the chances of developing life-threatening illnesses. Pyroptosis, a newfound form of lytic programmed cell death initiated by
Externí odkaz:
https://doaj.org/article/7d04351bf18c456a97e1709657282b98
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Human bone marrow mesenchymal stem cells (hBMSCs) are adult stem cells residing in the bone marrow, characterized by their capacity for multi-directional differentiation, self-renewal, migration, and engraftment. Serving as seed cells, BMSCs
Externí odkaz:
https://doaj.org/article/247b56ae35e54ec38a93f1fe22a0b83a
Publikováno v:
Frontiers in Physiology, Vol 15 (2024)
Mitophagy is a highly precise process of selective autophagy, primarily aimed at eliminating excess or damaged mitochondria to maintain the stability of both mitochondrial and cellular homeostasis. In recent years, with in-depth research into the ass
Externí odkaz:
https://doaj.org/article/d8a4574f99664bc4a1d5168e4d1f6c5b
Publikováno v:
Pharmacological Research, Vol 202, Iss , Pp 107144- (2024)
Fibrosis is a pathological process that affects multiple organs and is considered one of the major causes of morbidity and mortality in multiple diseases, resulting in an enormous disease burden. Current studies have focused on fibroblasts and myofib
Externí odkaz:
https://doaj.org/article/202ebf445b9942c69d084893e7c4ceb5
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Modeling and remodeling are essential processes in the development and refinement of maxillofacial bones. Dysregulated bone modeling during the developmental stage may lead to maxillofacial bone malformations and malocclusion. Bone remodeling under m
Externí odkaz:
https://doaj.org/article/6b20d8bcb3264eab8d51c0f13c10c95c
Autor:
Zekun Zhou, Jianfei Tang, Yixuan Lu, Jia Jia, Tiao Luo, Kaixin Su, Xiaohan Dai, Haixia Zhang, Ousheng Liu
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-16 (2023)
Abstract Background Head and neck squamous cell carcinoma (HNSCC) remains an unmet medical challenge. Metabolic reprogramming is a hallmark of diverse cancers, including HNSCC. Methods We investigated the metabolic profile in HNSCC by using The Cance
Externí odkaz:
https://doaj.org/article/6d825ce6051246f78fa98f39bf255c16
Autor:
Sang-A Park, Yun-Ji Lim, Wai Lim Ku, Dunfang Zhang, Kairong Cui, Liu-Ya Tang, Cheryl Chia, Peter Zanvit, Zuojia Chen, Wenwen Jin, Dandan Wang, Junji Xu, Ousheng Liu, Fu Wang, Alexander Cain, Nancy Guo, Hiroko Nakatsukasa, Chuan Wu, Ying E. Zhang, Keji Zhao, WanJun Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
IL-9-producing CD4 T (Th9) cells have been implicated in allergy and tumor immunity, but how their differentiation is regulated by TGFβ is still unclear. Here the authors show that two transcription factors, DBP and E2F8, institute opposing effects
Externí odkaz:
https://doaj.org/article/bc8c2332443143d3a8f42e69ddee3045
Autor:
Xian Cheng, Yanqing Yang, Zhengwei Liao, Qiao Yi, Yueying Zhou, Xiaohan Dai, Yanping Liu, Ousheng Liu
Publikováno v:
Frontiers in Bioengineering and Biotechnology, Vol 11 (2023)
Oral submucous fibrosis is a chronic, inflammatory and potentially malignant oral disease. Local delivery of triamcinolone to lesion site is a commonly used therapy. The existing methods for local drug delivery include topical administration and subm
Externí odkaz:
https://doaj.org/article/344f625e7df64eb0baf42e68e4c88208
Autor:
Yueying Zhou, Xiaonan Xin, Lichao Wang, Binsheng Wang, Li Chen, Ousheng Liu, David W. Rowe, Ming Xu
Publikováno v:
npj Regenerative Medicine, Vol 6, Iss 1, Pp 1-5 (2021)
Abstract The osteogenic potential of bone marrow mesenchymal stem cells (BMSCs) declines dramatically with aging. By using a calvarial defect model, we showed that a senolytic cocktail (dasatinib+quercetin; D + Q) improved osteogenic capacity of aged
Externí odkaz:
https://doaj.org/article/d85585d8cbab4ac3bee8a3ae54a2b293
Autor:
Zizheng Zou, Xiyuan Hu, Tiao Luo, Zhengnan Ming, Xiaodan Chen, Li Xia, Wensong Luo, Jijia Li, Na Xu, Ling Chen, Dongsheng Cao, Min Wen, Fanrong Kong, Kunjian Peng, Yuanzhu Xie, Xuan Li, Dayou Ma, Chuanyu Yang, Ceshi Chen, Wenjun Yi, Ousheng Liu, Suyou Liu, Junli Luo, Zhiyong Luo
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Arginine addiction induced by argininosuccinate synthase (ASSN1) deficiency has been exploited to treat ASS1-deficient cancers. Here, the authors show an alternative therapeutic approach where ASS1 activity is increased by the pesticide spinosyn A an
Externí odkaz:
https://doaj.org/article/cdf3151bd1624747889b50910c492a74