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Autor:
Manuel J. Carrasco, Suman Alishetty, Mohamad-Gabriel Alameh, Hooda Said, Lacey Wright, Mikell Paige, Ousamah Soliman, Drew Weissman, Thomas E. Cleveland, Alexander Grishaev, Michael D. Buschmann
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-15 (2021)
Carrasco et al. report a method that can predict the lipid nanoparticles (LNP) pKa from the structure of the ionizable lipid. They investigate the delivery efficiency for intramuscular and intravascular administration and propose design principles to
Externí odkaz:
https://doaj.org/article/bbdbf3686db74c9385304e3b47673ec7