A deep-learning pipeline for the diagnosis and discrimination of viral, non-viral and COVID-19 pneumonia from chest X-ray images

Autor: Ming Gao, Ian Ziyar, Ting Chen, Xuan Zhang, Xiaohong Liu, Jian Yang, Yong Liang, Winston Wang, Johnson Y.N. Lau, Ruiyun Deng, Zhihan Yan, Linsen Ye, Lianghong Zheng, Ye Sang, Kai Wang, Weimin Li, Laurance L Lau, Xiaoguang Zou, Oulan Li, Lingyan Zhang, Kang Zhang, Manson Fok, Wen Chen, Evis Sala, Longjiang Zhang, Zehong Yang, Jin Wang, Guiping Lin, Jun Shen, Tao Xu, Guangming Lu, Weihua Liao, Chengdi Wang, Zhongguo Zhou, Tianxin Lin, Charlotte Zhang, Tao Yu, Long Mo, Wenhua Liang, Andrea Olvera, Guangyu Wang, Jianxing He, Carola-Bibiane Schönlieb, Huimin Cai, Jichan Shi, Guiqun Cao, Zhihuan Li, Michael S. Roberts, Wei Chen, Wenqin Xu, Lei Yang, Xingwang Wu, Jun Liu

Publikováno v: Nature biomedical engineering

Common lung diseases are first diagnosed using chest X-rays. Here, we show that a fully automated deep-learning pipeline for the standardization of chest X-ray images, for the visualization of lesions and for disease diagnosis can identify viral pneu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f74f3d319f5574d7e1699ce7b03ed207
https://doi.org/10.1038/s41551-021-00704-1

DNA methylation markers in the diagnosis and prognosis of common leukemias

Autor: Gen Li, Guangxi Zang, Daniel Zhang, Qingli Quan, Ru Zhang, Wenge Hao, Jian-Kang Zhu, Edward Zhang, Xinping Cui, Xin Sun, Ian Ziyar, Runze Zhang, Zhiying Ou, Charlotte Zhang, Kang Zhang, Huiyan Luo, Oulan Li, Yingyi He, Xiaohong Zhang, Tina Poon, Linhai Cheng, Xiaoqiong Gu, Wei Wei, Shaoqing Wu, Zhihuan Li, Taylor Shimizu, Meixing Yu, Liya He, Lianghong Zheng, Jie Zhu, Hua Jiang, Jiayi Wang

Publikováno v: Signal Transduction and Targeted Therapy
Signal Transduction and Targeted Therapy, Vol 5, Iss 1, Pp 1-10 (2020)

The ability to identify a specific type of leukemia using minimally invasive biopsies holds great promise to improve the diagnosis, treatment selection, and prognosis prediction of patients. Using genome-wide methylation profiling and machine learnin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66efd4611c9a81ef70b56939da0ec61d
https://doi.org/10.1038/s41392-019-0090-5

Clinically Applicable AI System for Accurate Diagnosis, Quantitative Measurements, and Prognosis of COVID-19 Pneumonia Using Computed Tomography

Autor: Liang Liang, Yunfei Zha, Jiaming Li, Ruiyun Deng, Haiping Yin, Winston Wang, Charlotte Zhang, Jun Shen, Huimin Cai, Shaoxu Wu, Ming Gao, Li Wang, Liu Lu, Guangyu Wang, Jie Xu, Lianghong Zheng, Xuan Zhang, Liang Li, Zehong Yang, Oulan Li, Xiaohong Liu, Yong Zhou, Tianxin Lin, Linsen Ye, Ye Sang, Kang Zhang, Jianxing He, Wenqin Xu, Lei Yang, Zhongguo Zhou, Xingwang Wu, Tao Wu, Wenhua Liang, Zhihuan Li, Manson Fok, Weimin Li, Wei Zhang, Ke Wang, Wenjia Cai, Johnson Y.N. Lau, Jin Wang, Chengdi Wang, Kang Wei, Shanping Jiang, Ting Chen

Publikováno v: Cell

Summary Many COVID-19 patients infected by SARS-CoV-2 virus develop pneumonia (called novel coronavirus pneumonia, NCP) and rapidly progress to respiratory failure. However, rapid diagnosis and identification of high-risk patients for early intervent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::208c27f9d5d80cb9850f54cc8f6ffeaf
https://doi.org/10.1016/j.cell.2020.04.045

P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma

Autor: Carolyn Zin, Pamela L. Mellon, Jing Luo, Danni Lin, Michael Ai, Wenqiu Wang, Ling Zhao, Daniel Chen, Michael G. Rosenfeld, Zheng Zhong, Liangfang Zhang, Ken Flagg, William Shi, Emily Yeh, Kang Zhang, Jie Zhu, Catherine Shi, Yizhi Liu, Maryam Jafari, Sherrina Patel, Sheng Zhong, Ruben Abagyan, Lianghong Zheng, Gen Li, Yanxin Xu, Hongrong Luo, Dorota Skowronska-Krawczyk, Robert N. Weinreb, Weiwei Gao, Guiqun Cao, Cindy Wen, Martin Krupa, Jin Zhu, Hong Ouyang, Christopher Chung, Yehong Zhuo, Xiaodong Sun, Michal Krawczyk, Oulan Li

Publikováno v: Molecular Cell, vol 59, iss 6
Molecular cell, vol 59, iss 6
Skowronska-Krawczyk, D; Zhao, L; Zhu, J; Weinreb, RN; Cao, G; Luo, J; et al.(2015). P16INK4a Upregulation Mediated by SIX6 Defines Retinal Ganglion Cell Pathogenesis in Glaucoma. Molecular Cell, 59(6), 931-940. doi: 10.1016/j.molcel.2015.07.027. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/2wj3h2qz

© 2015 Elsevier Inc. Glaucoma, a blinding neurodegenerative disease, whose risk factors include elevated intraocular pressure (IOP), age, and genetics, is characterized by accelerated and progressive retinal ganglion cell (RGC) death. Despite decade

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a06b275bcc39f3d203df61e22d86ce38

Efficacy of quadruple therapy with clarithromycin based on faecal molecular antimicrobial susceptibility tests as first-line treatment for Helicobacter pylori infection: a protocol of a single-centre, single-blind, randomised clinical trial in China

Autor: Yan Li, Hao Wu, Jun Ye, Yujing Wang, Oulan Liao, Yaoyi Wu, Qin Du, Xiaochen Liu, Guochun Lou

Publikováno v: BMJ Open, Vol 13, Iss 7 (2023)

Introduction Helicobacter pylori is the most well-known risk factor for gastric cancer. Antibiotic resistance is the main reason for the failure of H. pylori eradication, and understanding the antibiotic resistance before treatment may be the main de

Externí odkaz: https://doaj.org/article/1214f98ce1d349ffa01c5ee0f150646c