Zobrazeno 1 - 10 of 118 pro vyhledávání: '"Oude Elferink, R. P."'
1
Cholestatic pruritus. New insights into pathophysiology and current treatment
Autor: Kremer, A. E., Oude Elferink, R. P. J., Beuers, U.
Publikováno v: Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete, 63(7), 532-538. Springer Verlag
Pruritus is a common symptom of hepatobiliary disorders and may considerably diminish quality of life. Cholestatic pruritus exerts a circadian rhythm and is typically most severe in the evening hours and early at night. Itching is reported often to b
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::698ac491f33692c65452bee843844148
https://pure.amc.nl/en/publications/cholestatic-pruritus-new-insights-into-pathophysiology-and-current-treatment(da1d4442-5966-49bb-89e4-f337bf2702ec).html
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8
MDR1 P-glycoprotein transports endogenous opioid peptides
Autor: Oude Elferink, R. P., Zadina, J.
Publikováno v: Peptides, 22(12), 2015-2020. Elsevier Inc.
MDR1 P-glycoprotein is generally regarded as an efflux pump for amphipathic toxic compounds. The question remains, however, whether certain endogenous compounds are also substrates for this transporter. Certain peptides have been shown to interact wi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::7c1097288c1875743012ebd22cadb221
https://pure.amc.nl/en/publications/mdr1-pglycoprotein-transports-endogenous-opioid-peptides(9a9d9905-a160-431f-8c5b-06076d899218).html
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9
Lack of UGT1 isoforms in Gunn rats changes metabolic ratio and facilitates excretion of the food-derived carcinogen 2-amino-1-methyl-6-phenylimidazo
Autor: Dietrich, C. G., Ottenhoff, R., de Waart, D. R., Oude-Elferink, R. P.
Publikováno v: Toxicology and applied pharmacology, 170(2), 137-143. Academic Press Inc.
UDP-glucuronosyltransferases (UGTs) play an important role in detoxification of endo- and xenobiotics. Deficiencies of these enzymes can have serious consequences, for example, in Crigler-Najjar disease Type I. Recently it was shown that the activate
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::a48c2a35cdcab56e3389d695b02c3977
https://pure.amc.nl/en/publications/lack-of-ugt1-isoforms-in-gunn-rats-changes-metabolic-ratio-and-facilitates-excretion-of-the-foodderived-carcinogen-2amino1methyl6phenylimidazo(800653f8-e4d8-42f0-ae14-8310d9b360df).html
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10
Lack of enteral nutrition during critical illness is associated with profound decrements in biliary lipid concentrations
Autor: de Vree, J. M., Romijn, J. A., Mok, K. S., Mathus-Vliegen, L. M., Stoutenbeek, C. P., Ostrow, J. D., Tytgat, G. N., Sauerwein, H. P., Oude Elferink, R. P., Groen, A. K.
Publikováno v: American journal of clinical nutrition, 70(1), 70-77. American Society for Nutrition
BACKGROUND: Food in the intestine drives the enterohepatic circulation of bile components. OBJECTIVE: We investigated whether parenteral or enteral delivery of nutrients alters serum and biliary lipids in critically ill patients. DESIGN: Eight intens
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=narcis______::7738ebf8492122031b50be0390f847f5
https://pure.amc.nl/en/publications/lack-of-enteral-nutrition-during-critical-illness-is-associated-with-profound-decrements-in-biliary-lipid-concentrations(eb70aab6-82d3-4d55-8573-47fb5139d567).html
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