Kidney Transplant Recipient Attitudes Toward a SARS-CoV-2 Vaccine

Autor: Michael T. Ou, BS, Brian J. Boyarsky, MD, Laura B. Zeiser, ScM, Teresa Po-Yu Chiang, MD, MPH, Jake Ruddy, BS, Sarah E. Van Pilsum Rasmussen, BA, Jennifer Martin, Jennifer St. Clair Russell, PhD, MSEd, MCHES, Christine M. Durand, MD, Robin K. Avery, MD, William A. Werbel, MD, Matthew Cooper, MD, Allan B. Massie, PhD, MHS, Dorry L. Segev, MD, PhD, Jacqueline M. Garonzik-Wang, MD, PhD

Publikováno v: Transplantation Direct, Vol 7, Iss 7, p e713 (2021)

Background. A widely accepted severe acute respiratory syndrome 2 (SARS-CoV-2) vaccine could protect vulnerable populations, but the willingness of solid organ transplant recipients (SOTRs) to accept a potential vaccine remains unknown. Methods. We c

Externí odkaz: https://doaj.org/article/849ce0396d6d4005a3cfadbc8e1aa618

Saponin nanoparticle adjuvants incorporating Toll-like receptor agonists drive distinct immune signatures and potent vaccine responses.

Autor: Ou BS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Baillet J; Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA., Filsinger Interrante MV; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA.; Stanford Biophysics Program, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.; Stanford Medical Scientist Training Program, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA., Adamska JZ; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA., Zhou X; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Saouaf OM; Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA., Yan J; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Klich JH; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Jons CK; Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA., Meany EL; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Valdez AS; Department of Biochemistry, University of Washington, Seattle, WA 98109, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Carter L; Department of Biochemistry, University of Washington, Seattle, WA 98109, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Pulendran B; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.; Department of Microbiology & Immunology, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.; Department of Pathology, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA., King NP; Department of Biochemistry, University of Washington, Seattle, WA 98109, USA.; Institute for Protein Design, University of Washington, Seattle, WA 98195, USA., Appel EA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Department of Materials Science & Engineering, Stanford University, Stanford, CA 94305, USA.; Stanford ChEM-H, Stanford University, Stanford, CA 94305, USA.; Institute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics-Endocrinology, Stanford University School of Medicine, Stanford University, Stanford, CA 94305, USA.; Woods Institute for the Environment, Stanford University, Stanford CA 94305, USA.

Publikováno v: Science advances [Sci Adv] 2024 Aug 09; Vol. 10 (32), pp. eadn7187. Date of Electronic Publication: 2024 Aug 07.

Nanoparticle-Conjugated Toll-Like Receptor 9 Agonists Improve the Potency, Durability, and Breadth of COVID-19 Vaccines.

Autor: Ou BS; Department of Bioengineering, Stanford University, Stanford, California 94305, United States., Baillet J; Department of Materials Science & Engineering, Stanford University, Stanford, California 94305, United States., Picece VCTM; Department of Materials Science & Engineering, Stanford University, Stanford, California 94305, United States.; Department of Chemistry and Applied Biosciences, ETH Zurich, Zurich 8093, Switzerland., Gale EC; Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, United States., Powell AE; Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, United States.; Stanford ChEM-H, Stanford University, Stanford, California 94305, United States., Saouaf OM; Department of Materials Science & Engineering, Stanford University, Stanford, California 94305, United States., Yan J; Department of Bioengineering, Stanford University, Stanford, California 94305, United States., Nejatfard A; Department of Biochemistry, Stanford University School of Medicine, Stanford, California 94305, United States., Lopez Hernandez H; Department of Materials Science & Engineering, Stanford University, Stanford, California 94305, United States., Appel EA; Department of Bioengineering, Stanford University, Stanford, California 94305, United States.; Department of Materials Science & Engineering, Stanford University, Stanford, California 94305, United States.; Stanford ChEM-H, Stanford University, Stanford, California 94305, United States.; Department of Pediatrics - Endocrinology, Stanford University School of Medicine, Stanford, California 94305, United States.; Woods Institute for the Environment, Stanford University, Stanford, California 94305, United States.

Publikováno v: ACS nano [ACS Nano] 2024 Jan 30; Vol. 18 (4), pp. 3214-3233. Date of Electronic Publication: 2024 Jan 12.

A regimen compression strategy for commercial vaccines leveraging an injectable hydrogel depot technology for sustained vaccine exposure.

Autor: Yan J, Ou BS, Saouaf OM, Meany EL, Eckman N, Appel EA

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2023 Mar 25. Date of Electronic Publication: 2023 Mar 25.

Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors.

Autor: Grosskopf AK; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA., Labanieh L; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Klysz DD; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA., Roth GA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Xu P; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA., Adebowale O; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA., Gale EC; Department of Biochemistry, Stanford University, Stanford, CA 94305, USA., Jons CK; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA., Klich JH; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Yan J; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Maikawa CL; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Correa S; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA., Ou BS; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., d'Aquino AI; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA., Cochran JR; Department of Chemical Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA., Chaudhuri O; Department of Mechanical Engineering, Stanford University, Stanford, CA 94305, USA., Mackall CL; Center for Cancer Cell Therapy, Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA., Appel EA; Department of Bioengineering, Stanford University, Stanford, CA 94305, USA.; Department of Materials Science and Engineering, Stanford University, Stanford, CA 94305, USA.; Department of Pediatrics, Stanford University School of Medicine, Stanford, CA 94305, USA.; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA.; ChEM-H Institute, Stanford University, Stanford, CA 94305, USA.; Woods Institute for the Environment, Stanford University, Stanford, CA 94305, USA.

Publikováno v: Science advances [Sci Adv] 2022 Apr 08; Vol. 8 (14), pp. eabn8264. Date of Electronic Publication: 2022 Apr 08.