Zobrazeno 1 - 10
of 89
pro vyhledávání: '"Otto Windl"'
Publikováno v:
Free Neuropathology, Vol 5 (2024)
Background: The postmortem diagnostic of individuals having suffered presumptive neurodegenerative disease comprises exclusion of a prion disease, extensive brain sampling and histopathological evaluation, which are resource-intensive and time consum
Externí odkaz:
https://doaj.org/article/ccfed883cf2541b0ab86c200b079d639
Autor:
Christina V. Tauber, Sigrid C. Schwarz, Thomas W. Rösler, Thomas Arzberger, Steve Gentleman, Otto Windl, Mandy Krumbiegel, André Reis, Viktoria C. Ruf, Jochen Herms, Günter U. Höglinger
Publikováno v:
Acta Neuropathologica Communications, Vol 11, Iss 1, Pp 1-19 (2023)
Abstract The MAPT gene, encoding the microtubule-associated protein tau on chromosome 17q21.31, is result of an inversion polymorphism, leading to two allelic variants (H1 and H2). Homozygosity for the more common haplotype H1 is associated with an i
Externí odkaz:
https://doaj.org/article/ae97f9d9d91942cbbbf9d8ff8dee7c6c
Autor:
Sabina Eigenbrod, Petra Frick, Uwe Bertsch, Gerda Mitteregger-Kretzschmar, Janina Mielke, Marko Maringer, Niklas Piening, Alexander Hepp, Nathalie Daude, Otto Windl, Johannes Levin, Armin Giese, Vignesh Sakthivelu, Jörg Tatzelt, Hans Kretzschmar, David Westaway
Publikováno v:
PLoS ONE, Vol 12, Iss 12, p e0188989 (2017)
Prion diseases have been linked to impaired copper homeostasis and copper induced-oxidative damage to the brain. Divalent metal ions, such as Cu2+ and Zn2+, bind to cellular prion protein (PrPC) at octapeptide repeat (OR) and non-OR sites within the
Externí odkaz:
https://doaj.org/article/768e6387c51240a48de92b6362f601c9
Autor:
Dongseob Tark, Hyojin Kim, Michael H Neale, Minjeong Kim, Hyunjoo Sohn, Yoonhee Lee, Insoo Cho, Yiseok Joo, Otto Windl
Publikováno v:
PLoS ONE, Vol 10, Iss 2, p e0115939 (2015)
Bovine spongiform encephalopathy (BSE) is a zoonotic transmissible spongiform encephalopathy (TSE) thought to be caused by the same prion strain as variant Creutzfeldt-Jakob disease (vCJD). Unlike scrapie and chronic wasting disease there is no cell
Externí odkaz:
https://doaj.org/article/1dff60b9f0b945318550878889c392ca
Autor:
Emeka A Okoroma, Diane Purchase, Hemda Garelick, Roger Morris, Michael H Neale, Otto Windl, Oduola O Abiola
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e68099 (2013)
The prion agent is notoriously resistant to common proteases and conventional sterilisation procedures. The current methods known to destroy prion infectivity such as incineration, alkaline and thermal hydrolysis are harsh, destructive, environmental
Externí odkaz:
https://doaj.org/article/04b48e1ef4fd4f3da1b3b1046e97d553
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14207 (2010)
Bovine spongiform encephalopathy (BSE) is a fatal, transmissible, neurodegenerative disease of cattle. To date, the disease process is still poorly understood. In this study, brain tissue samples from animals naturally infected with BSE were analysed
Externí odkaz:
https://doaj.org/article/2ba7f9286c1442b1acfcc1504090ad53
Autor:
Umberto Agrimi, Romolo Nonno, Giacomo Dell'Omo, Michele Angelo Di Bari, Michela Conte, Barbara Chiappini, Elena Esposito, Giovanni Di Guardo, Otto Windl, Gabriele Vaccari, Hans-Peter Lipp
Publikováno v:
PLoS Pathogens, Vol 4, Iss 7, p e1000113 (2008)
The bank vole is a rodent susceptible to different prion strains from humans and various animal species. We analyzed the transmission features of different prions in a panel of seven rodent species which showed various degrees of phylogenetic affinit
Externí odkaz:
https://doaj.org/article/ea5bb8a51be549899b3c862f30467628
Autor:
Sigrun Roeber, Eva-Maria Grasbon-Frodl, Otto Windl, Bjarne Krebs, Wei Xiang, Caren Vollmert, Thomas Illig, Andreas Schröter, Thomas Arzberger, Petra Weber, Inga Zerr, Hans A Kretzschmar
Publikováno v:
PLoS ONE, Vol 3, Iss 5, p e2147 (2008)
Clinical and pathological changes in familial Creutzfeldt-Jakob disease (CJD) cases may be similar or indistinguishable from sporadic CJD. Therefore determination of novel mutations in PRNP remains of major importance. We identified two different rar
Externí odkaz:
https://doaj.org/article/8a4ffef9c9444945a38ec0d3dc6f99e0
Autor:
Sigrun Roeber, Eva-Maria Grasbon-Frodl, Otto Windl, Bjarne Krebs, Wei Xiang, Caren Vollmert, Thomas Illig, Andreas Schröter, Thomas Arzberger, Petra Weber, Inga Zerr, Hans A. Kretzschmar
Publikováno v:
PLoS ONE, Vol 3, Iss 5 (2008)
Externí odkaz:
https://doaj.org/article/c05a6794b5da4d12875585a6facad569
Autor:
Alessandra Fanciulli, Fabian Leys, Fabienne Lehner, Victoria Sidoroff, Viktoria C Ruf, Cecilia Raccagni, Philipp Mahlknecht, Demy J S Kuipers, Wilfred F J van IJcken, Heike Stockner, Thomas Musacchio, Jens Volkmann, Camelia Maria Monoranu, Iva Stankovic, Guido Breedveld, Federico Ferraro, Christina Fevga, Otto Windl, Jochen Herms, Stefan Kiechl, Werner Poewe, Klaus Seppi, Nadia Stefanova, Sonja W Scholz, Vincenzo Bonifati, Gregor K Wenning
Publikováno v:
Brain Communications, 4(4):175. Oxford University Press
Multiple system atrophy is considered a sporadic disease, but neuropathologically confirmed cases with a family history of parkinsonism have been occasionally described. Here we report a North-Bavarian (colloquially, Lion’s tail region) six-generat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4250df49ab37247d6b0dc96b18d476ad
https://doi.org/10.1093/braincomms/fcac175
https://doi.org/10.1093/braincomms/fcac175