Zobrazeno 1 - 10
of 43
pro vyhledávání: '"Otto R Frey"'
Autor:
Pascal Probst, Katrin Hoffmann, Markus A Weigand, Adrian Billeter, Rosa Klotz, Jan Larmann, Anastasia Murtha-Lemekhova, Juri Fuchs, Miriam Teroerde, Heike Rau, Otto R Frey, Daniel Hornuss, Ute Chiriac
Publikováno v:
BMJ Open, Vol 12, Iss 9 (2022)
Introduction Surgical site infections (SSIs) are among the most common complications after abdominal surgery and develop in approximately 20% of patients. These patients suffer a 12% increase in mortality, underlying the need for strategies reducing
Externí odkaz:
https://doaj.org/article/0314d21a98174ddaa89efaa635a9aead
Autor:
Ute Chiriac, Daniel Richter, Otto R. Frey, Anka C. Röhr, Sophia Helbig, Stefan Hagel, Uwe Liebchen, Markus A. Weigand, Alexander Brinkmann
Publikováno v:
Antibiotics, Vol 12, Iss 7, p 1112 (2023)
Various studies have reported insufficient beta-lactam concentrations in critically ill patients. The optimal dosing strategy for beta-lactams in critically ill patients, particularly in septic patients, is an ongoing matter of discussion. This retro
Externí odkaz:
https://doaj.org/article/5689093f639e4ab4a532bf7386c1ddbf
Autor:
Rawan Alraish, Sebastian G. Wicha, Otto R. Frey, Anka C. Roehr, Johann Pratschke, Martin Stockmann, Tilo Wuensch, Magnus Kaffarnik
Publikováno v:
Annals of Intensive Care, Vol 10, Iss 1, Pp 1-9 (2020)
Abstract Background In critically ill patients, tigecycline (TGC) remains an important therapeutic option due to its efficacy against multiresistant Gram-positive and Gram-negative bacteria. TGC is metabolized and eliminated predominantly by the live
Externí odkaz:
https://doaj.org/article/ed651372be7f461492268892b1da5ad3
Autor:
Stefan Hagel, Sandra Fiedler, Andreas Hohn, Alexander Brinkmann, Otto R. Frey, Heike Hoyer, Peter Schlattmann, Michael Kiehntopf, Jason A. Roberts, Mathias W. Pletz, on behalf of the TARGET Study Group
Publikováno v:
Trials, Vol 20, Iss 1, Pp 1-10 (2019)
Abstract Background Sepsis is a life-threatening organ dysfunction caused by a dysregulated host response to infection with a hospital mortality in excess of 40%. Along with insufficient and delayed empirical antimicrobial therapy, inappropriate anti
Externí odkaz:
https://doaj.org/article/744932445d87406bb2de0054cf0f0eba
Autor:
Dzenefa Alihodzic, Sebastian G. Wicha, Otto R. Frey, Christina König, Michael Baehr, Dominik Jarczak, Stefan Kluge, Claudia Langebrake
Publikováno v:
Pharmaceutics, Vol 14, Iss 5, p 965 (2022)
Extracorporeal membrane oxygenation (ECMO) is utilized to temporarily sustain respiratory and/or cardiac function in critically ill patients. Ciprofloxacin is used to treat nosocomial infections, but data describing the effect of ECMO on its pharmaco
Externí odkaz:
https://doaj.org/article/0085cf68ce0c4b249e2743b50c2b662a
Autor:
Sebastian G. Wicha, Rawan Alraish, Magnus Kaffarnik, Anka C Roehr, Martin Stockmann, Otto R Frey, Tilo Wuensch, Johann Pratschke
Publikováno v:
Technology and Health Care. 30:309-321
BACKGROUND: Critically ill patients commonly suffer from infections that require antimicrobial therapy. In previous studies, liver dysfunction was shown to have an essential impact on the dose selection in these patients. This pilot study aims to ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::50c2d8046b068e59802593a19d04d0d2
https://doi.org/10.3233/thc-191847
https://doi.org/10.3233/thc-191847
Autor:
Hendrik Booke, Otto R. Frey, Anka C. Röhr, Ute Chiriac, Kai Zacharowski, Tomas Holubec, Elisabeth H. Adam
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-8 (2021)
The scope of extracorporeal membrane oxygenation (ECMO) is expanding, nevertheless, pharmacokinetics in patients receiving cardiorespiratory support are fairly unknown leading to unpredictable drug concentrations. Currently, there are no clear guidel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doajarticles::31c27fe41e65abfbab50b49484b2b8a1
https://doaj.org/article/50dee264d34a4e94a6aa66b22bf86e69
https://doaj.org/article/50dee264d34a4e94a6aa66b22bf86e69
Publikováno v:
Krankenhaushygiene up2date. 16:187-201
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3c21817e781348d637407913ae9e0477
https://doi.org/10.1055/a-1173-5813
https://doi.org/10.1055/a-1173-5813
Autor:
Ute Chiriac, Heike Rau, Otto R. Frey, Anka C. Röhr, Sabrina Klein, Anna L. Meyer, Benedict Morath
Publikováno v:
Antibiotics; Volume 11; Issue 5; Pages: 541
Dalbavancin is emerging as a promising alternative in the ambulant treatment of gram-positive infections that require long-term antibiotic treatment such as osteomyelitis, prosthetic joint infections, and endocarditis. The aim of the current study wa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c6019d6f9489b5be55459b0d2e29865
https://pubmed.ncbi.nlm.nih.gov/35625185
https://pubmed.ncbi.nlm.nih.gov/35625185
Autor:
Kai Zacharowski, Christoph Tiede, Florian J Raimann, Daniel Dubinski, Christian Senft, Natalie Filmann, Ute Chiriac, Otto R Frey, Anna Wieduwilt, Volker Seifert, Michael Eibach, Jan Mersmann, Anka C Röhr
Publikováno v:
Antibiotics, Vol 10, Iss 1421, p 1421 (2021)
Antibiotics
Volume 10
Issue 11
Antibiotics
Volume 10
Issue 11
Effective antibiotic therapy of cerebral infections such as meningitis or ventriculitis is hindered by low penetration into the cerebrospinal fluid (CSF). Because continuous infusion of meropenem and vancomycin and routine therapeutic drug monitoring
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce24ee8f25d567347b977d6e9b172378
https://www.mdpi.com/2079-6382/10/11/1421
https://www.mdpi.com/2079-6382/10/11/1421