The Effects of Single Strains and Mixtures of Probiotic Bacteria on Immune Profile in Liver, Spleen, and Peripheral Blood

Autor: Fiona Long Yan Fong, Hani El-Nezami, Otto Mykkänen, Pirkka V. Kirjavainen

Publikováno v: Frontiers in Nutrition, Vol 9 (2022)

Probiotic bacteria have potential use as immunomodulators but comparative data on their immunological effects are very limited. The aim of this study was to characterize the effect of oral administration of probiotic strains, alone or as mixtures, on

Externí odkaz: https://doaj.org/article/8f44ab07f868443184563aea22d4e29d

REDUCTION OF SUBACUTE ENDOTOXEMIA COULD MEDIATE BENEFICIAL EFFECTS OF VACCINIUM MYRTILLUS IN METABOLIC SYNDROME - A PBMC GENE EXPRESSION STUDY

Autor: Pirkka V. Kirjavainen, Leena Pulkkinen, Otto Mykkänen, Michiel E. Adriaens, Riitta Törrönen, Riitta Puupponen-Pimiä, Marjukka Kolehmainen, David E. Laaksonen, Kaisa Poutanen, Hannu Mykkänen

Publikováno v: Mykkänen, O T, Kirjavainen, P V, Pulkkinen, L, Mykkänen, H, Törrönen, R, Kolehmainen, M, Adriaens, M, Laaksonen, D E, Puupponen-Pimiä, R & Poutanen, K 2014, ' Reduction of subacute endotoxemia could mediate beneficial effects of vaccinium myrtillus in metabolic syndrome-A PBMC gene expression study ', Acta Horticulturae, vol. 1017, no. January, pp. 369-380 . https://doi.org/10.17660/ActaHortic.2014.1017.45

Obesity and its consequences on cardiometabolic health have been associated to low-grade inflammation. Anthocyanins are anti-inflammatory compounds in diet, and the major group of polyphenols found in wild European blueberries, bilberries (Vaccinium

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf24364c1788d75ed835f5ff13322747
https://doi.org/10.17660/actahortic.2014.1017.45

Fecal and urinary excretion of aflatoxin B1 metabolites (AFQ1, AFM1 and AFB-N7-guanine) in young Chinese males

Autor: Huilian Zhu, Jing Ma, Hani El-Nezami, Wenhua Ling, Hannu Mykkänen, Risto O. Juvonen, Otto Mykkänen, Nektaria Polychronaki, Seppo Salminen, Heidi Kemiläinen, Eeva Salminen

Publikováno v: International Journal of Cancer. 115:879-884

Our study was designed to assess the fecal and urinary excretion of 3 aflatoxin B1 (AFB1) metabolites, aflatoxins M1 (AFM1) and Q1 (AFQ1) and aflatoxin B1-N7-guanine (AFB-N7-guanine) that are produced by the predominant forms of cytochrome P450 enzym

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb9dcb239805d857062019890d0a396e
https://doi.org/10.1002/ijc.20951

Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome

Autor: David E. Laaksonen, Helena Gylling, Michiel E. Adriaens, Riitta Törrönen, Kaisa Poutanen, Maarit Hallikainen, Tiina Leppänen, Eeva Moilanen, Pirkka V. Kirjavainen, Otto Mykkänen, Hannu Mykkänen, Leena Pulkkinen, Riitta Puupponen-Pimiä, Marjukka Kolehmainen

Publikováno v: Kolehmainen, M, Mykkänen, O, Kirjavainen, P V, Leppänen, T, Moilanen, E, Adriaens, M, Laaksonen, D E, Hallikainen, M, Puupponen-Pimiä, R, Pulkkinen, L, Mykkänen, H, Gylling, H, Poutanen, K & Törrönen, R 2012, ' Bilberries reduce low-grade inflammation in individuals with features of metabolic syndrome ', Molecular Nutrition and Food Research, vol. 56, no. 10, pp. 1501-1510 . https://doi.org/10.1002/mnfr.201200195
Molecular Nutrition & Food Research, 56(10), 1501-1510. Wiley

Scope: Low‐grade inflammation is a hallmark of cardiometabolic risk. Bilberries (Vaccinium myrtillus) are rich in polyphenols with potential anti‐inflammatory properties. We studied the impact of bilberries on inflammation and gene expression pro

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7ad27ced70ffba493c16905efc3bfce
https://cris.vtt.fi/en/publications/6b63db30-fd1d-47b9-a272-783ed16c6b6a

High-fiber rye bread improves bowel function in postmenopausal women but does not cause other putatively positive changes in the metabolic activity of intestinal microbiota

Autor: Katri S. Juntunen, Otto Mykkänen, Jaana Mättö, Kaisa Poutanen, Hannu Mykkänen, Hani El-Nezami, Herman Adlercreutz, Soile M. Gråsten

Publikováno v: Gråsten, S, Juntunen, K, Mättö, J, Mykkänen, O, El-Nezami, H, Adlercreutz, H, Poutanen, K & Mykkänen, H 2007, ' High-fiber rye bread improves bowel function in postmenopausal women but does not cause other putatively positive changes in the metabolic activity of intestinal microbiota ', Nutrition Research, vol. 27, no. 8, pp. 454-461 . https://doi.org/10.1016/j.nutres.2007.05.010

We have reported previously that rye bread (RB) as a part of the conventional diet affects bowel function and the metabolic activity of the microbiota differently in men and women. Because a higher intake of fiber by men could explain the difference

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7874a7d80a86bdacf047642dc3a574ce
https://cris.vtt.fi/en/publications/76b84c3c-d8c0-4af3-aadc-c214244b9e05