Zobrazeno 1 - 10
of 64
pro vyhledávání: '"Otto Kucera"'
Publikováno v:
Acta Medica, Vol 64, Iss 1, Pp 1-7 (2021)
Non-Alcoholic Fatty Liver Disease (NAFLD) is one of the most important causes of liver disease worldwide leading the foreground cause of liver transplantation. Recently miRNAs, small non-coding molecules were identified as an important player in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26848c76949d222d649974d16eb9c089
https://actamedica.lfhk.cuni.cz/64/1/0001/
https://actamedica.lfhk.cuni.cz/64/1/0001/
Publikováno v:
Archives of Physiology and Biochemistry. 128:985-992
Context: Monoestolides belonging to the fatty acid-hydroxy fatty acid (FAHFA) family have recently emerged as promising insulin sensitizers.Objective: To investigate and compare impact of two selected FAHFA isomers, namely 9-hexadecanoyloxy-octadecan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7061e04aa05ece13e9ebd20135e6dca7
https://doi.org/10.1080/13813455.2020.1743322
https://doi.org/10.1080/13813455.2020.1743322
Autor:
Zuzana Červinková, Pavla Staňková, Karolína Vaněčková, Jan Polak, Moustafa Elkalaf, Otto Kucera
Publikováno v:
Journal of Visualized Experiments.
Mitochondrial substrate flux is a distinguishing characteristic of each cell type, and changes in its components such as transporters, channels, or enzymes are involved in the pathogenesis of several diseases. Mitochondrial substrate flux can be stud
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fe4a15e5426bd3966a9111a203fbbc4
https://doi.org/10.3791/62902-v
https://doi.org/10.3791/62902-v
Autor:
Tumisang Edward Maseko, Eva Peterová, Moustafa Elkalaf, Darja Koutová, Jan Melek, Pavla Staňková, Veronika Špalková, Reem Matar, Halka Lotková, Zuzana Červinková, Otto Kučera
Publikováno v:
Biomolecules, Vol 14, Iss 9, p 1179 (2024)
Various strategies have been employed to improve the reliability of 2D, 3D, and co-culture in vitro models of nonalcoholic fatty liver disease, including using extracellular matrix proteins such as collagen I to promote cell adhesion. While studies h
Externí odkaz:
https://doaj.org/article/f49d5b3112a34a999a8e994a2eb89568
Autor:
Paloma Gallego, Jordi Muntané, Zuzana Cervinková, Tumisang E. Maseko, Otto Kucera, Pavla Staňková, Patricia de la Cruz-Ojeda, Elena Navarro-Villarán, José A Del Campo, María A. Rodríguez-Hernández, Moustafa Elkalaf
Publikováno v:
Digital.CSIC: Repositorio Institucional del CSIC
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Consejo Superior de Investigaciones Científicas (CSIC)
Digital.CSIC. Repositorio Institucional del CSIC
instname
Hepatocellular carcinoma (HCC) is the most common type of primary liver cancer and the fourth most frequent cause of cancer-related death worldwide. Sorafenib is the first line recommended therapy for patients with locally advanced/metastatic HCC. Th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::863c042fa6378033b83e8a84d2c13048
http://hdl.handle.net/10261/239964
http://hdl.handle.net/10261/239964
Publikováno v:
Drug and Chemical Toxicology. 40:448-456
Acetaminophen (APAP) hepatotoxicity is often studied in primary cultures of hepatocytes of various species, but there are only few works comparing interspecies differences in susceptibility of hepatocytes to APAP in vitro.The aim of our work was to c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb48563e390af8bf413feae9837d321
https://doi.org/10.1080/01480545.2016.1255953
https://doi.org/10.1080/01480545.2016.1255953
Autor:
José A Del Campo, Moustafa Elkalaf, Zuzana Červinková, Paloma Gallego, Patricia de la Cruz-Ojeda, Pavla Staňková, M. Ángeles Rodríguez-Hernández, Tumisang E. Maseko, Jordi Muntané, Otto Kucera, Elena Navarro-Villarán
Publikováno v:
Free Radical Biology and Medicine. 165:54
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb5a9aa56231256698cdb4fb549d9521
https://doi.org/10.1016/j.freeradbiomed.2020.12.418
https://doi.org/10.1016/j.freeradbiomed.2020.12.418
Autor:
Zuzana Červinková, Otto Kucera, O Sobotka, Khurum Hakeem, David Rychtrmoc, René Endlicher, Z Drahota, Marjan Raad
Publikováno v:
Journal of Bioenergetics and Biomembranes. 48:363-373
A compound with promising anticancer properties, 3-bromopyruvate (3-BP) is a synthetic derivative of a pyruvate molecule; however, its toxicity in non-malignant cells has not yet been fully elucidated. Therefore, we elected to study the effects of 3-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff3c044927a76e88b078b9a2bfc27ef
https://doi.org/10.1007/s10863-016-9674-8
https://doi.org/10.1007/s10863-016-9674-8
Publikováno v:
Acta Medica, Vol 59, Iss 2, Pp 35-42 (2016)
Aim: The aim of our study was to assess whether simple steatosis impairs liver regeneration after partial hepatectomy (PHx) in rats. Methods: Male Sprague–Dawley rats were fed a standard diet (ST-1, 10% kcal fat) and high-fat diet (HFD, 71% kcal fa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e7dc49c88606c27d698d04eb1927d896
https://doi.org/10.14712/18059694.2016.87
https://doi.org/10.14712/18059694.2016.87
Publikováno v:
General physiology and biophysics. 38(4)
Non-alcoholic fatty liver disease and its complications are frequent causes of liver-related morbidity and mortality. Incretin glucagon-like peptide-1 (GLP-1) affects liver functions and metabolism. Although GLP-1 analogues are widely used in clinica
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de3f30217387a20d1849448ab973897
https://pubmed.ncbi.nlm.nih.gov/31241045
https://pubmed.ncbi.nlm.nih.gov/31241045