Zobrazeno 1 - 10
of 73
pro vyhledávání: '"Otto KA"'
Publikováno v:
Frontiers in Genetics, Vol 7 (2016)
Liver cancer is the third most common cancer type and the second leading cause of deaths in men. Large population studies have demonstrated remarkable gender disparities in the incidence and the cumulative risk of liver cancer. A number of emerging r
Externí odkaz:
https://doaj.org/article/b80814156b744cd581e55e6f39e48867
Autor:
John Wong, Feng Wu, Weiqin Yang, Myth T.S. Mok, Jie Chen, Wenshu Tang, Alfred S. L. Cheng, Joseph J.Y. Sung, Anthony W.H. Chan, Ka Fai To, Zhiwei Chen, Philip Chun Yeung, Man Liu, Minhu Chen, Paul B.S. Lai, Jingying Zhou, Hongchuan Jin, Xiaoyu Liu, Xuezhen Zeng, Stephen L. Chan, Yu Feng, Hanyong Sun, Otto Ka-Wing Cheung
Publikováno v:
Gut. 69:365-379
ObjectiveHepatocellular carcinoma (HCC), mostly developed in fibrotic/cirrhotic liver, exhibits relatively low responsiveness to immune checkpoint blockade (ICB) therapy. As myeloid-derived suppressor cell (MDSC) is pivotal for immunosuppression, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ed1ec52d60e981ae9aa02d7ba90fd841
https://doi.org/10.1136/gutjnl-2018-317257
https://doi.org/10.1136/gutjnl-2018-317257
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-10 (2024)
Abstract The sucrose preference test is a popular test for anhedonia in the chronic unpredictable stress model of depression. Yet, the test does not always produce consistent results. Long food and water deprivation before the test, while often imple
Externí odkaz:
https://doaj.org/article/9420dd2e72d54c2a8fef89ca1bd29d4a
Autor:
Paul B.S. Lai, Zhiwei Chen, Feng Wu, Hanyong Sun, Kevin Y. Yip, Jingying Zhou, Ka Fai To, Yuan Tian, Patrick Tan, Otto Ka-Wing Cheung, Alfred S. L. Cheng, Liangliang Xu, Stephen L. Chan, Wing Hung Chan, Weiqin Yang, Joseph J.Y. Sung, Yu Feng, Zhiwu Tan, John Wong
Publikováno v:
Abstracts.
Background The insufficient T cell infiltration into non-inflamed tumors such as hepatocellular carcinoma (HCC) restricts the effectiveness of immune-checkpoint blockade (ICB) to a minority of patients. Epigenetic therapy provides new opportunities t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::63876849d09314170346b00aba09599d
https://doi.org/10.1136/gutjnl-2020-iddf.40
https://doi.org/10.1136/gutjnl-2020-iddf.40
Akademický článek
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Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-6 (2023)
Abstract A digital society is fragile and vulnerable to space-originated electromagnetic disturbances. Global geomagnetic conditions have been actively monitored since the invention of the magnetometer in 1833. However, regional changes in the magnet
Externí odkaz:
https://doaj.org/article/09e2bb59f8254ed282f0f7656000ce54
Autor:
Pia Kahnau, Paul Mieske, Jenny Wilzopolski, Otto Kalliokoski, Silvia Mandillo, Sabine M. Hölter, Vootele Voikar, Adriana Amfim, Sylvia Badurek, Aleksandra Bartelik, Angela Caruso, Maša Čater, Elodie Ey, Elisabetta Golini, Anne Jaap, Dragan Hrncic, Anna Kiryk, Benjamin Lang, Natasa Loncarevic-Vasiljkovic, Hamid Meziane, Aurelija Radzevičienė, Marion Rivalan, Maria Luisa Scattoni, Nicolas Torquet, Julijana Trifkovic, Brun Ulfhake, Christa Thöne-Reineke, Kai Diederich, Lars Lewejohann, Katharina Hohlbaum
Publikováno v:
BMC Biology, Vol 21, Iss 1, Pp 1-23 (2023)
Abstract Background Traditionally, in biomedical animal research, laboratory rodents are individually examined in test apparatuses outside of their home cages at selected time points. However, the outcome of such tests can be influenced by various fa
Externí odkaz:
https://doaj.org/article/0f1a3a77ba124af3a174d67a64fb17f7
Akademický článek
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Autor:
Ka Fai To, Kevin Y. Yip, Joseph J.Y. Sung, Feng Wu, Alfred S. L. Cheng, Yalin Tu, Jing Wang, Paul B.S. Lai, Zhiwei Chen, Zhiwu Tan, Yu Feng, Jianquan Cao, Hanyong Sun, Anthony W.H. Chan, Yuan Tian, Stephen L. Chan, Jingying Zhou, Weiqin Yang, Wenshu Tang, Patrick Boon-Ooi Tan, Liangliang Xu, Otto Ka-Wing Cheung, John Wong
Publikováno v:
Science translational medicine. 13(588)
Insufficient T cell infiltration into noninflamed tumors, such as hepatocellular carcinoma (HCC), restricts the effectiveness of immune-checkpoint blockade (ICB) for a subset of patients. Epigenetic therapy provides further opportunities to rewire ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56f972bb2442dd3035cb4beace9ca28c
https://pubmed.ncbi.nlm.nih.gov/33827976
https://pubmed.ncbi.nlm.nih.gov/33827976
Autor:
Yuan Tian, Paul B.S. Lai, Alfred S. L. Cheng, Yaocheng Rui, Yue-Sun Cheung, Nan Li, Shu-Qun Cheng, Bo Yang, Jianjun Luo, Joseph J.Y. Sung, Pengyuan Yang, Hongyang Wang, Bin Yang, Yajing Hao, Runsheng Chen, Weiqin Yang, William K.K. Wu, Zhenxing Zhang, Otto Ka-Wing Cheung, Weinan Qiu, Zhangjun Lin
Publikováno v:
Nature Communications
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome that elevates the risk of hepatocellular carcinoma (HCC). Although alteration of lipid metabolism has been increasingly recognized as a hallmark of cance
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eecc04bfd9b99db0414f95fe4e677b33
http://europepmc.org/articles/PMC6662851
http://europepmc.org/articles/PMC6662851