Zobrazeno 1 - 10
of 104
pro vyhledávání: '"Otto Hromatka"'
Publikováno v:
Monatshefte f�r Chemie. 105:123-126
The synthesis of 5-(o-trifluoromethylphenyl)-1H-thieno-[3,4-e]1,4-diazepin-2(3H)-one (7) and its nitration and chlorination in pos. 8 are described.
Autor:
Christian R. Noe, Georg Habison, Yves A. Bara, Michael Feifel, Friedrich Leierer, Otto Hromatka, Johannes E. Blum, Dieter Binder
Publikováno v:
Archiv der Pharmazie. 313:636-644
Synthese und Pharmakologie der Titelverbindungen 9–14 werden beschrieben. Thiophene as a Structural Element of Physiologically Active Compounds, V: 5-(o-Nitrophenyl)thieno[2,3-e][1,4]diazepines Synthesis and pharmacological properties of the title
Publikováno v:
Monatshefte f�r Chemie. 105:127-134
The syntheses of ethyl 4-amino-2-trifluormethyl-thiophene-3-carboxylate (14) and of ethyl 3-amino-5-trifluormethylthiophene-2-carboxylate (15) are described.
Publikováno v:
Monatshefte f�r Chemie. 106:375-379
The synthesis of the title compound6 c, starting with the condensation of o-phenylenediamine and methyl 4-oxotetrahydrothiophene-3-carboxylate (1) to 1.3.4.9-tetrahydrothieno[3.4-b] [1.5]benzodiazepin-10-one (2), is described.
Publikováno v:
Monatshefte f�r Chemie. 106:213-218
The preparation of 3-hydroxy-5-phenyl-pyrrol-2-carboxamides and their methylation and acetylation are described.
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 106:1103-1109
The preparation of 7-chloro-1,3-dihydro-5-phenyl-thieno-[3,2-e]-1,4-diazepin-2-one (8 a) and 7-chloro-5-(2-chlorophenyl)-1,3-dihydro-thieno[3,2-e]1,4-diazepin-2-one (8 b) as well as the methylation in position 1 are described.
Autor:
Rudolf Dr. Pfister, Karl Schmied, Konrad Strub, Christian R. Noe, Kaspar Burri, Paul Zeller, Otto Hromatka, Franz Geissler, Dieter Binder
Publikováno v:
Journal of Medicinal Chemistry. 30:678-682
The synthesis of tenoxicam, 4-hydroxy-2-methyl-N-2-pyridyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxami de 1,1-dioxide (1e), and of the analogues with various residues on the ring nitrogen and the amide nitrogen is described. This new class of "oxicams"
Autor:
Johannes E. Blum, Dieter Binder, Werner Veit, Friedrich Hillebrand, Otto Hromatka, Christian R. Noe
Publikováno v:
Archiv der Pharmazie. 313:587-602
Synthese und Pharmakologie der Titelverbindungen 13, 15, 16 und 17 werden beschrieben. Thiophene as a Structural Element of Physiologically Active Compounds, IV: o-Substituted 5-Phenylthieno[2,3-e][1,4]diazepines. Synthesis and pharmacological proper
Publikováno v:
Monatshefte f�r Chemie. 106:555-558
The synthesis of 1-(3-thienyl)-benzimidazol-2-ones (3 a and4), described in an earlier paper1, has been further investigated. The Na-salt of3 a is converted to a benzimidazolone substituted in position 3 (3 b). Dehydrogenation of the thiophene nucleu
Publikováno v:
Monatshefte f�r Chemie. 105:1164-1169
The synthesis of in position 4 substituted thieno[3.4-b]quinoline-9(4H)-ones (6) by aromatization of 1.4-dihydrothieno[3.4-b]quinoline-9(3H)-ones (4) and attempts to cyclize 4-phenylamino-3-thiophenecarboxylic acid (3c), or derivatives thereof, to co