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Autor:
Otto Dungan, Shawn Dormann, Sandra Fernandes-Denney, Brian Duffy, Daniel Effiong, William Kerr, John Chisholm
A new synthetic route to the SHIP1 agonist AQX-1125 has been developed. This sequence utilizes a hydroxy-acid intermediate which allows for ready differentiation of the C6 and C7 positions. The role of the C17 alkene in the biological activity of the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0087ac4d0707b3956be4e32a9444e5c2
https://doi.org/10.26434/chemrxiv-2021-vdnql
https://doi.org/10.26434/chemrxiv-2021-vdnql