Zobrazeno 1 - 10
of 191
pro vyhledávání: '"Otto Dideberg"'
Autor:
Carine Bebrone, Jean Martinez, Jean-François Hernandez, Lionel Nauton, Laurent Gavara, Gülhan Turan-Zitouni, Filomena De Luca, Paola Sandra Mercuri, Ludovic T. Maillard, Jean Denis Docquier, Silvia Tanfoni, Moreno Galleni, Katja Becker, Pauline Lonjon, Jean-Marie Frère, Laurent Sevaille, Ciarán Condon, Carole Guyon, Maud E. S. Achard, Julia Dzieciolowski, Lionel Benard, Luisa Borgianni, Otto Dideberg
Publikováno v:
ChemMedChem
ChemMedChem, 2017, 12 (12), pp.972-985. ⟨10.1002/cmdc.201700186⟩
ChemMedChem, Wiley-VCH Verlag, 2017, 12 (12), pp.972-985. ⟨10.1002/cmdc.201700186⟩
ChemMedChem, 2017, 12 (12), pp.972-985. ⟨10.1002/cmdc.201700186⟩
ChemMedChem, Wiley-VCH Verlag, 2017, 12 (12), pp.972-985. ⟨10.1002/cmdc.201700186⟩
52nd International Conference on Medicinal Chemistry (RICT) of the French-Medicinal-Chemistry-Society (SCT) - Interfacing Chemical Biology and Drug Discovery -- JUL 06-08, 2016 -- Caen, FRANCE
WOS: 000403905300014
PubMed ID: 28505394
M
WOS: 000403905300014
PubMed ID: 28505394
M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ead690922d65ad0d0620d66be43309c2
https://hal.science/hal-02923462
https://hal.science/hal-02923462
Autor:
Bm M. R. Liénard, Le E. Horsfall, Cj J. Schofield, Jm M. Frère, Otto Dideberg, Moreno Galleni, Gianpiero Garau
Publikováno v:
Horsfall, L E, Garau, G, Liénard, B M R, Dideberg, O, Schofield, C J, Frère, J M & Galleni, M 2007, ' Competitive inhibitors of the CphA metallo-beta-lactamase from Aeromonas hydrophila ', Antimicrobial Agents and Chemotherapy, vol. 51, no. 6, pp. 2136-42 . https://doi.org/10.1128/AAC.00866-06
Various inhibitors of metallo-β-lactamases have been reported; however, none are effective for all subgroups. Those that have been found to inhibit the enzymes of subclass B2 (catalytically active with one zinc) either contain a thiol (and show less
Publikováno v:
FEMS Microbiology Reviews. 30:673-691
Bacterial cell division and daughter cell formation are complex mechanisms whose details are orchestrated by at least a dozen different proteins. Penicillin-binding proteins (PBPs), membrane-associated macromolecules which play key roles in the cell
Publikováno v:
Journal of Biological Chemistry. 280:28591-28600
Streptococcus pneumoniae is the worldwide leading cause of deaths from invasive infections such as pneumoniae, sepsis, and meningitidis in children and the elderly. Nasopharyngeal colonization, which plays a key role in the development of pneumococca
Autor:
Thierry Vernet, Otto Dideberg, Andréa Dessen, Anne Marie Di Guilmi, Pauline Macheboeuf, Viviana Job
Publikováno v:
Proceedings of the National Academy of Sciences. 102:577-582
Bacterial cell division is a complex, multimolecular process that requires biosynthesis of new peptidoglycan by penicillin-binding proteins (PBPs) during cell wall elongation and septum formation steps. Streptococcus pneumoniae has three bifunctional
Autor:
Moreno Galleni, Otto Dideberg, Carine Bebrone, Gianpiero Garau, Jean-Marie Frère, Christine Anne
Publikováno v:
Journal of Molecular Biology. 345:785-795
One strategy developed by bacteria to resist the action of beta-lactam antibiotics is the expression of metallo-beta-lactamases. CphA from Aeromonas hydrophila is a member of a clinically important subclass of metallo-beta-lactamases that have only o
Autor:
André Zapun, Cécile Morlot, Audrey Le Gouellec, Otto Dideberg, Thierry Vernet, Marjolaine Noirclerc-Savoye
Publikováno v:
Molecular Microbiology. 55:413-424
DivIB, DivIC and FtsL are bacterial proteins essential for cell division, which show interdependencies for their stabilities and localization. We have reconstituted in vitro a trimeric complex consisting of the recombinant extracellular domains of th
Autor:
Otto Dideberg, Sergey Tcherniuk, Max H. Nanao, Andréa Dessen, Maxim Y. Balakirev, Jadwiga Chroboczek
Publikováno v:
EMBO reports. 5:783-788
Ubiquitylation, the modification of cellular proteins by the covalent attachment of ubiquitin, is critical for diverse biological processes including cell cycle progression, signal transduction and stress response. This process can be reversed and re
Autor:
Paola Sandra Mercuri, Kris De Vriendt, Bart Devreese, Otto Dideberg, Iris Thamm, Jean-Marie Frère, Jozef Van Beeumen, I. Garcia-Saez, Moreno Galleni, Gian Maria Rossolini
Publikováno v:
Journal of Biological Chemistry. 279:33630-33638
The subclass B3 FEZ-1 beta-lactamase produced by Fluoribacter (Legionella) gormanii is a Zn(II)-containing enzyme that hydrolyzes the beta-lactam bond in penicillins, cephalosporins, and carbapenems. FEZ-1 has been extensively studied using kinetic,
Autor:
Thierry Vernet, Laurent Chesnel, Julie Hopkins, Jacques Croize, Estelle Pagliero, Anne Marie Di Guilmi, Otto Dideberg
Publikováno v:
Antimicrobial Agents and Chemotherapy. 48:1848-1855
Extensive use of β-lactam antibiotics has led to the selection of pathogenic streptococci resistant to β-lactams due to modifications of the penicillin-binding proteins (PBPs). PBP2b from Streptococcus pneumoniae is a monofunctional (class B) high-