Zobrazeno 1 - 10
of 521
pro vyhledávání: '"Otto C, Boerman"'
Autor:
Jan Marie de Gooyer, Fortuné M. K. Elekonawo, Andreas J. A. Bremers, Otto C. Boerman, Erik H. J. G. Aarntzen, Philip R. de Reuver, Iris. D. Nagtegaal, Mark Rijpkema, Johannes H. W. de Wilt
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-10 (2022)
Imaging of tumor burden during surgery can lead to better tumor resection. Here, the authors develop a fluorescent probe that binds to carcinoembryonic antigen, expressed on colorectal cancer cells, and describe the results of their phase I clinical
Externí odkaz:
https://doaj.org/article/88e964c101f84c1c99ce8e827c6c5f1d
Autor:
Jeannette C. Oosterwijk-Wakka, Mirjam C.A. de Weijert, Gerben M. Franssen, Dimitar R. Kolev, Ton A.F.J. de Haan, Otto C. Boerman, Peter F.A. Mulders, Egbert Oosterwijk
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 32, Iss , Pp 100826- (2022)
Sunitinib is an effective treatment for patients with metastatic Renal Cell Carcinoma (mRCC) but ultimately resistance occurs. The aim of this study was to investigate sunitinib resistance in RCCs and to develop therapeutic combination strategies wit
Externí odkaz:
https://doaj.org/article/a3206bae57544db090053ce0eb8b6ee7
Autor:
Fokko J. Huizing, Bianca A.W. Hoeben, Jasper Lok, Otto C. Boerman, Sandra Heskamp, Johan Bussink
Publikováno v:
Physics and Imaging in Radiation Oncology, Vol 19, Iss , Pp 145-150 (2021)
Background and purpose: Tumor hypoxia is an important cause of radioresistance and is associated with poor outcome.SPECT (Single-photon emission computed tomography) imaging enables visualizing tumor characteristics. We investigated the SPECT-radiotr
Externí odkaz:
https://doaj.org/article/dd2fd80f825e474d993f5860a5309827
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-9 (2019)
Abstract Background In colorectal cancer, survival of patients is drastically reduced when complete resection is hampered by involvement of critical structures. Targeted photodynamic therapy (tPDT) is a local and targeted therapy which could play a r
Externí odkaz:
https://doaj.org/article/5523c9df0a1845419f4d497734b6833c
Autor:
Fortuné M. K. Elekonawo, Susanne Lütje, Gerben M. Franssen, Desirée L. Bos, David M. Goldenberg, Otto C. Boerman, Mark Rijpkema
Publikováno v:
EJNMMI Research, Vol 9, Iss 1, Pp 1-8 (2019)
Abstract Background Image-guided surgery may improve surgical outcome for colorectal cancer patients. Here, we evaluated the feasibility of a pretargeting strategy for multimodal imaging in colorectal cancer using an anti-carcinoembryonic antigen (CE
Externí odkaz:
https://doaj.org/article/e2e7958bd07d4dc48ab3c9639744312f
Autor:
Inja Waldhauer, Valeria Gonzalez-Nicolini, Anne Freimoser-Grundschober, Tapan K Nayak, Linda Fahrni, Ralf J. Hosse, Danny Gerrits, Edwin J. W. Geven, Johannes Sam, Sabine Lang, Esther Bommer, Virginie Steinhart, Elisabeth Husar, Sara Colombetti, Erwin Van Puijenbroek, Markus Neubauer, J. Mark Cline, Pradeep K. Garg, Gregory Dugan, Federica Cavallo, Gonzalo Acuna, Jehad Charo, Volker Teichgräber, Stefan Evers, Otto C. Boerman, Marina Bacac, Ekkehard Moessner, Pablo Umaña, Christian Klein
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Simlukafusp alfa (FAP-IL2v, RO6874281/RG7461) is an immunocytokine comprising an antibody against fibroblast activation protein α (FAP) and an IL-2 variant with a retained affinity for IL-2Rβγ > IL-2 Rβγ and abolished binding to IL-2 Rα. Here,
Externí odkaz:
https://doaj.org/article/92299c28b9d34a45bf95cf39c2bbc494
Autor:
Wael A. Eter, Inge Van der Kroon, Karolina Andralojc, Mijke Buitinga, Stefanie M. A. Willekens, Cathelijne Frielink, Desiree Bos, Lieke Joosten, Otto C. Boerman, Maarten Brom, Martin Gotthardt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-6 (2017)
Abstract Pancreatic islet transplantation is a promising therapy for patients with type 1 diabetes. However, the duration of long-term graft survival is limited due to inflammatory as well as non-inflammatory processes and routine clinical tests are
Externí odkaz:
https://doaj.org/article/54496705e6054b69a78f30ff906bdda1
Autor:
Lieke Joosten, Maarten Brom, Martin K. H. Schäfer, Otto C. Boerman, Eberhard Weihe, Martin Gotthardt
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
Abstract There is an ongoing search for new tracers to optimize imaging of beta cell-derived tumors (insulinomas). The PAC1 receptor, expressed by insulinomas, can be used for targeting of these tumors. Here, we investigated whether radiolabeled maxa
Externí odkaz:
https://doaj.org/article/15cd8f038ddf48b98c71877b796995fd
Autor:
Willemijn A. Hobo, Erik H.J.G. Aarntzen, Harry Dolstra, Otto C. Boerman, Johan Bussink, Daniel Olive, Jeannette Cany, Soley Thordardottir, Gerwin W. Sandker, Janneke D.M. Molkenboer-Kuenen, Peter J. Wierstra, Sandra Heskamp
Antibodies that block the interaction between programmed death ligand 1 (PD-L1) and PD-1 have shown impressive responses in subgroups of patients with cancer. PD-L1 expression in tumors seems to be a prerequisite for treatment response. However, PD-L
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcf012cc714ed1a4486ab1a6ea08d03a
https://doi.org/10.1158/2326-6066.c.6548185.v1
https://doi.org/10.1158/2326-6066.c.6548185.v1
Autor:
Willemijn A. Hobo, Erik H.J.G. Aarntzen, Harry Dolstra, Otto C. Boerman, Johan Bussink, Daniel Olive, Jeannette Cany, Soley Thordardottir, Gerwin W. Sandker, Janneke D.M. Molkenboer-Kuenen, Peter J. Wierstra, Sandra Heskamp
Supplemental Figure 3
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29084ab7ab3d6eca96b2a2699dff722c
https://doi.org/10.1158/2326-6066.22536622
https://doi.org/10.1158/2326-6066.22536622