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Akademický článek

Low-Dose Antibiotic Prophylaxis Induces Rapid Modifications of the Gut Microbiota in Infants With Vesicoureteral Reflux

Publikováno v: Frontiers in Pediatrics, Vol 9 (2021)

Background and Objectives: Maturation of the gut microbiota (GM) in infants is critically affected by environmental factors, with potential long-lasting clinical consequences. Continuous low-dose antibiotic prophylaxis (CAP) is the standard of care f

Externí odkaz: https://doaj.org/article/41b6f543eeb04fe2ab59a0f84912ce3a

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Face-to-face Sun Protection Training and Text Messages Improve Sun Protection Behaviour in Adolescent Organ Transplant Recipients: HIPPOlino Feasibility Study

Autor: Günter Klaus, Ingeborg Jahn, Lars Pape, Michael Max Sachse, Otto Mehls, Mareike Barz, Gudrun Laschewski, Silke Böttcher, Hajo Zeeb, Gunnar Wagner

Publikováno v: Acta dermato-venereologica, 96(3): 341–345

Adolescent organ transplant recipients have an increased risk of developing skin cancer. The aim of this study was to evaluate the technical feasibility and acceptability of short messaging service-based sun protection recommendations for adolescent

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3f5c7434e4f292042d5b87a84f8f58b
https://doi.org/10.2340/00015555-2234

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Pathogens causing urinary tract infections in infants: a European overview by the ESCAPE study group

Publikováno v: European Journal of Pediatrics. 174:783-790

PubMedID: 25428232 Knowledge of the distribution spectrum of causative organisms and their resistance patterns has become a core requirement for the rational and effective management of urinary tract infections. In the context of a prospective trial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::044e9d8cb7ce552add58bcb59b98cd05
https://doi.org/10.1007/s00431-014-2459-3

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Height Gain in Ullrich-Turner Syndrome after Early and Late Growth Hormone Treatment Start: Results from a Large Retrospective German Study and Potential Basis for an Individualized Treatment Approach

Autor: Otto Mehls, Michael B. Ranke, H. G. Doerr, Berthold P. Hauffa, Markus Bettendorf, Ioana Inta

Publikováno v: Hormone Research in Paediatrics. 80:356-362

Background: Ullrich-Turner syndrome (UTS) girls often present with short stature in adolescence to the endocrinologist when the efficacy of growth hormone (GH) to improve growth remains unknown and parameters to estimate individual GH responsiveness

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d80dd90f7726c8c274e6d76005ef6f2d
https://doi.org/10.1159/000356045

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Growth hormone treatment after renal transplantation: a promising but underused chance to improve growth

Autor: Otto Mehls, Richard N. Fine

Publikováno v: Pediatric Nephrology. 28:1-4

Growth retardation remains a clinical problem in children with chronic kidney disease (CKD) prior to and during end-stage renal disease. The growth of approximately 40 % of children on dialysis is stunted. Even so, growth hormone treatment (GH) is no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce1b36d86f1400c237547db47d1bf642
https://doi.org/10.1007/s00467-012-2293-7

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Dosing of glucocorticosteroids in nephrotic syndrome

Autor: Otto Mehls, Peter F. Hoyer

Publikováno v: Pediatric Nephrology. 26:2095-2098

Pharmacodynamic actions and molecular mechanisms of corticosteroids in patients with nephrotic syndrome (NS) are poorly understood. The role of immunosuppressive and of directstabilizingeffectsonthepodocytecytoskeletonneedsto be defined. Without prec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dcd781c8e260b24d38b151abc563b960
https://doi.org/10.1007/s00467-011-1993-8

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Different relationships between the first 2 years on growth hormone treatment and the d3-growth hormone receptor polymorphism in short small-for-gestational-age (SGA) children

Autor: Tilman R Rohrer, Otto Mehls, Roland Pfäffle, Berthold P. Hauffa, Nikolaus Stahnke, Michael B. Ranke, Helmuth G. Dörr, Markus Bettendorf

Publikováno v: Clinical Endocrinology. 75:656-660

Summary Background There has been controversy in recent years on whether the d3 polymorphism of the GH receptor is associated with a better growth response to GH in idiopathic short children born small for gestational age (SGA). Methods In this prosp

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9c54c063df7d4782b1d199ce01b2de03
https://doi.org/10.1111/j.1365-2265.2011.04104.x

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Growth and body composition in very young SGA children

Autor: Otto Mehls, Vicente Barrios, Jesús Argente

Publikováno v: Pediatric Nephrology. 25:679-685

Infants with a very low birth weight are at risk of a reduced number of nephrons predisposing to kidney disorder, hypertension, and metabolic syndrome. Approximately 3% of infants are born small for gestational age (SGA), defined as birth weight and/

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::168420cac773f8e1848ddccd724bfe7e
https://doi.org/10.1007/s00467-009-1432-2

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Differential Regulation of RGS-2 by Constant and Oscillating PTH Concentrations

Autor: C. P. Schmitt, Franz Schaefer, Otto Mehls, M. Hömme

Publikováno v: Calcified Tissue International. 84:305-312

PTH has diverse effects on bone metabolism: anabolic when given intermittently, catabolic when given continuously. The cellular mechanisms underlying the varying target cell response are not clear yet. PTH induces RGS-2, a member of the Regulator of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e04c9d0927ccdc9f4b457e8779ae55c7
https://doi.org/10.1007/s00223-009-9222-1

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